Опубликована: Янв. 1, 2024
Язык: Английский
Micromachines, Год журнала: 2023, Номер 14(9), С. 1786 - 1786
Опубликована: Сен. 18, 2023
Exploring bio-inspired nanomaterials (BINMs) and incorporating them into micro/nanodevices represent a significant development in biomedical applications. Nanomaterials, engineered to imitate biological structures processes, exhibit distinctive attributes such as exceptional biocompatibility, multifunctionality, unparalleled versatility. The utilization of BINMs demonstrates potential diverse domains micro/nanodevices, encompassing biosensors, targeted drug delivery systems, advanced tissue engineering constructs. This article thoroughly examines the various BINMs, including those originating from proteins, DNA, biomimetic polymers. Significant attention is directed toward these entities subsequent ramifications that arise. review explores biomimicry’s structure–function correlations. Synthesis mosaics include bioprocesses, biomolecules, natural structures. These nanomaterials’ interfaces use functionalization geometric adaptations, transforming delivery, nanobiosensing, organ-on-chip cancer-on-chip models, wound healing dressing mats, antimicrobial surfaces. It provides an in-depth analysis existing challenges proposes prospective strategies improve efficiency, performance, reliability devices. Furthermore, this study offers forward-thinking viewpoint highlighting avenues for future exploration advancement. objective effectively utilize maximize application progression thereby propelling rapidly developing field its promising future.
Язык: Английский
Процитировано
63
Small, Год журнала: 2024, Номер unknown
Опубликована: Июль 26, 2024
Abstract Virus‐like particles (VLPs) are nanostructures composed of one or more structural proteins, exhibiting stable and symmetrical structures. Their precise compositions dimensions provide versatile opportunities for modifications, enhancing their functionality. Consequently, VLP‐based nanomaterials have gained widespread adoption across diverse domains. This review focuses on three key aspects: the mechanisms viral capsid protein self‐assembly into VLPs, design methods constructing multifunctional strategies synthesizing multidimensional using VLPs. It provides a comprehensive overview advancements in virus‐inspired functional nanomaterials, encompassing VLP assembly, functionalization, synthesis nanomaterials. Additionally, this explores future directions, opportunities, challenges field aiming to shed light potential prospects exciting area research.
Язык: Английский
Процитировано
5
Nanomedicine, Год журнала: 2025, Номер unknown, С. 1 - 4
Опубликована: Март 19, 2025
Язык: Английский
Процитировано
0
JACS Au, Год журнала: 2025, Номер unknown
Опубликована: Март 25, 2025
DNA nanotechnology has revolutionized materials science and biomedicine by enabling precise manipulation of matter at the nanoscale. nanostructures (DNs) in particular represent a promising frontier for targeted therapeutics. Engineered DNs offer unprecedented molecular programmability, biocompatibility, structural versatility, making them ideal candidates advanced drug delivery, organelle regulation, cellular function modulation. This Perspective explores emerging role modulating behavior through organelle-targeted interventions. We highlight current advances nuclear, mitochondrial, lysosomal targeting, showcasing applications ranging from gene delivery to cancer For instance, have enabled precision mitochondrial disruption cells, pH modulation enhance silencing, nuclear gene-editing templates. While hold immense promise advancing nanomedicine, outstanding challenges include optimizing biological interactions addressing safety concerns. highlights potential rational control organelles, which could lead novel therapeutic strategies advancement nanomedicines future.
Язык: Английский
Процитировано
0
Materials Today Bio, Год журнала: 2025, Номер unknown, С. 101726 - 101726
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13
Опубликована: Апрель 25, 2025
Colorectal cancer (CRC) remains a highly heterogeneous malignancy with significant morbidity and mortality worldwide. Despite advancements in surgery, chemotherapy, immunotherapy, targeted therapy, treatment efficacy is often hampered by drug resistance systemic toxicity. In recent years, nano-drug delivery systems (NDDS) have emerged as promising strategy to enhance therapeutic precision, reduce adverse effects, overcome CRC treatment. This review discusses the NDDS for treatment, focusing on optimization of oral systems, development tumor-specific targeting strategies, design intelligent responsive tumor microenvironment (TME). Furthermore, we summarize current challenges translation explore future research directions enhancing their clinical feasibility impact.
Язык: Английский
Процитировано
0
Coordination Chemistry Reviews, Год журнала: 2025, Номер 541, С. 216801 - 216801
Опубликована: Май 17, 2025
Язык: Английский
Процитировано
0
Chemical Engineering Journal, Год журнала: 2024, Номер 494, С. 152882 - 152882
Опубликована: Июнь 5, 2024
Язык: Английский
Процитировано
1
ChemistrySelect, Год журнала: 2024, Номер 9(31)
Опубликована: Авг. 14, 2024
Abstract Synthesis of nano‐particles using various greener approaches such as the use plant extract, microbes, etc. is gaining a lot popularity in scientific community due to their advantages being cheaper protocol, reduction less hazardous chemicals, more environmentally benign method and good yield. It has been previously reported by many research groups that material provides reducing, capping well stabilizing agents brings down biological environmental risks green synthesis nano‐particles. So it was thought worthwhile synthesize copper oxide (CuO NPs) some locally available medicinal plants. Rivina humilis L. plants which are our region Vidarbha Maharashtra State, India considered be herbal for treatment respiratory‐related disorders mainly asthma cold local tribal peoples. found contains variety phytochemicals can employed nanomaterials. With this aim present an efficient approach (RH) whole extract. For characterization bio‐synthesized CuO NPs, spectral analytical techniques UV‐Vis spectroscopy, FT‐IR, XRD, SEM, TEM, EDS were employed. The newly synthesized NPs also tested potential activities against six different bacterial stains namely E. coli , P. aeruginosa S. aureus vulgaris B. subtilis typhi diffusion method. antioxidant efficacy undertaken through 1,1‐Diphenyl‐2‐picrylhydrazyl (DPPH) free radical scavenging activity. Their results have presented discussed work.
Язык: Английский
Процитировано
1
Acta Biomaterialia, Год журнала: 2024, Номер unknown
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
1