Development and Psychopathology,
Год журнала:
2025,
Номер
unknown, С. 1 - 16
Опубликована: Май 26, 2025
Abstract
Background:
Paternal
perinatal
mental
health
influences
subsequent
child
development,
yet
is
under-investigated.
This
study
aims
to
examine
the
impact
of
different
timings
paternal
anxiety
(prenatal-only,
postnatal-only,
and
both
pre-and
postnatally)
on
children’s
emotional
behavioral
difficulties.
Method:
We
used
data
from
Avon
Longitudinal
Study
Parents
Children
tested
prospective
associations
between
in
fathers
adverse
outcomes
children
at
3
years,
6
months
7
months.
Results:
whose
were
anxious
period
higher
risk
outcomes,
compared
not
perinatally.
At
months,
highest
group
was
one
with
prenatally-only;
non-anxious
fathers,
prenatal-only
significantly
more
likely
present
difficulties,
measured
by
total
problems
(unadjOR
=
1.82,
95%CI
[1.28,
2.53]).
exposed
pre-
postnatally
any
psychiatric
disorder
2.35,
[1.60,
3.37])
group.
Conclusions:
a
factor
for
even
after
accounting
maternal
health,
temperament,
sociodemographic
factors,
should
be
overlooked
research
clinical
practice.
World Psychiatry,
Год журнала:
2024,
Номер
23(2), С. 191 - 208
Опубликована: Май 10, 2024
We
provide
here
the
first
bottom-up
review
of
lived
experience
mental
disorders
in
adolescents
co-designed,
co-conducted
and
co-written
by
experts
academics.
screened
first-person
accounts
within
outside
medical
field,
discussed
them
collaborative
workshops
involving
numerous
-
representing
different
genders,
ethnic
cultural
backgrounds,
continents
their
family
members
carers.
Subsequently,
material
was
enriched
phenomenologically
informed
perspectives
shared
with
all
collaborators.
The
inner
subjective
is
described
for
mood
disorders,
psychotic
attention-deficit/hyperactivity
disorder,
autism
spectrum
anxiety
eating
externalizing
self-harm
behaviors.
recollection
individuals'
past
histories
also
indexes
prodromal
(often
transdiagnostic)
features
predating
psychiatric
diagnosis.
wider
society
respect
to
family,
school
peers,
social
context.
Furthermore,
health
care
receiving
a
diagnosis
accessing
support,
psychopharmacological
treatment,
psychotherapy,
experiencing
peer
support
activism,
achieving
recovery.
These
findings
can
impact
clinical
practice,
research,
whole
society.
hope
that
this
journey
help
us
maintain
our
commitment
protecting
adolescents'
fragile
health,
develop
into
healthy,
fulfilling
contributing
adult
life.
Current Opinion in Psychiatry,
Год журнала:
2024,
Номер
37(6), С. 381 - 387
Опубликована: Авг. 22, 2024
The
incidence
of
eating
disorders
has
increased
worldwide.
This
narrative
review
gives
an
overview
research
on
etiology
and
risk
factors
published
in
2022-2024.
European Psychiatry,
Год журнала:
2025,
Номер
unknown, С. 1 - 37
Опубликована: Янв. 8, 2025
An
abstract
is
not
available
for
this
content
so
a
preview
has
been
provided.
As
you
have
access
to
content,
full
PDF
via
the
'Save
PDF'
action
button.
Psychological Medicine,
Год журнала:
2025,
Номер
55
Опубликована: Янв. 1, 2025
Abstract
Background
Psychosis
prediction
has
been
a
key
focus
of
psychiatry
research
for
over
20
years.
The
two
dominant
approaches
to
identifying
psychosis
risk
have
the
clinical
high-risk
(CHR)
and
familial
(FHR)
approaches.
To
date,
real-world
sensitivity
these
–
that
is,
proportion
all
future
psychotic
disorders
in
population
they
identify
not
systematically
reviewed.
Methods
We
reviewed
meta-analysed
studies
MEDLINE,
Embase,
PsychINFO,
Web
Science
(from
inception
until
September
2024)
reported
data
on
CHR
FHR
i.e.,
individuals
with
diagnosis
preceded
by
or
history
parental
(PROSPERO:
CRD42024542268).
Results
identified
four
reporting
relevant
data.
pooled
estimate
approach
was
6.7%
(95%
CI:
1.5–15.0%)
6.5%
4.4–8.9%).
There
high
level
heterogeneity
between
studies.
Most
had
low
bias,
but
most
bias.
Conclusion
Pooled
suggest
approaches,
each,
capture
only
about
6–7%
disorders.
These
findings
demonstrate
need
additional
psychosis.
Schizophrenia Bulletin,
Год журнала:
2024,
Номер
50(4), С. 881 - 890
Опубликована: Янв. 19, 2024
Abstract
Background
and
Hypothesis
Recent
research
showed
that
young
people
who
presented
to
hospital
with
self-harm
in
Finland
had
a
significantly
elevated
risk
of
later
psychosis.
We
investigated
the
prospective
relationship
between
presentation
for
psychosis
an
unprecedentedly
large
national
Swedish
cohort.
Study
Design
used
inpatient
outpatient
healthcare
registers
identify
all
individuals
born
1981
1993
were
alive
living
Sweden
on
their
12th
birthday
one
or
more
times
self-harm.
compared
them
matched
cohort,
followed
up
20
years,
cumulative
incidence
psychotic
disorders.
Furthermore,
we
examined
whether
strength
changed
over
time
by
examining
cohort
effects.
Results
In
total,
28
908
(2.0%)
without
prior
diagnosis
during
follow-up.
For
self-harm,
diagnosed
was
20.7%
at
years
follow-up
(hazard
radio
=
13.9,
95%
CI
13.3–14.6,
P-value
<5
×
10−308).
There
no
evidence
dilution
effect
time:
while
increased,
this
did
not
result
attenuation
subsequent
Conclusions
Individuals
present
teens
20s
represent
important
group
prediction
prevention.
Journal of Personalized Medicine,
Год журнала:
2023,
Номер
13(10), С. 1453 - 1453
Опубликована: Сен. 29, 2023
Background:
Duration
of
untreated
illness
(DUI)—defined
as
the
time
period
between
onset
a
mental
disorder
and
its
first
adequate
treatment—should
influence
patients’
long-term
prognosis
outcome.
In
patients
with
obsessive–compulsive
(OCD),
DUI
lasts
on
average
from
87.5
up
to
94.5
months,
being
significantly
longer
compared
data
available
affected
by
other
severe
disorders,
such
schizophrenia
bipolar
disorder.
We
carried
out
systematic
review
in
order
assess
impact
outcomes
OCD
patients.
Methods:
A
systemic
has
been
implemented,
searching
inception
April
2023;
only
papers
written
English
were
included.
Results:
Seventy-one
articles
initially
identified;
eight
included
review.
The
ranged
7.0
±
8.5
20.9
11.2
years.
Patients
reporting
have
poor
outcome
terms
lower
level
treatment
response
greater
symptom
severity.
Conclusions:
present
confirms
that
negative
OCD.
It
should
be
useful
promote
dissemination
early
interventions
specific
focus
symptoms.
Journal of Child Psychology and Psychiatry,
Год журнала:
2024,
Номер
65(8), С. 1072 - 1086
Опубликована: Янв. 14, 2024
Background
Youth
with
a
family
history
of
bipolar
disorder
(BD)
may
be
at
increased
risk
for
mood
disorders
and
developing
side
effects
after
antidepressant
exposure.
The
neurobiological
basis
these
risks
remains
poorly
understood.
We
aimed
to
identify
biomarkers
underlying
by
characterizing
abnormalities
in
the
brain
connectome
symptomatic
youth
familial
BD.
Methods
Depressed
and/or
anxious
(
n
=
119,
age
14.9
±
1.6
years)
BD
but
no
prior
exposure
typically
controls
57,
14.8
1.7
received
functional
magnetic
resonance
imaging
(fMRI)
during
an
emotional
continuous
performance
task.
A
generalized
psychophysiological
interaction
(gPPI)
analysis
was
performed
compare
their
patterns,
followed
machine
learning
topological
metrics.
Results
High‐risk
showed
weaker
connectivity
patterns
that
were
mainly
located
default
mode
network
(DMN)
(network
weight
50.1%)
relative
controls,
derived
from
visual
(VN)
constituted
largest
proportion
aberrant
stronger
pairs
54.9%).
Global
local
efficiency
E
,
p
.022)
clustering
coefficient
C
.029)
nodal
metrics
right
superior
frontal
gyrus
(SFG)
:
<
.001;
.001)
high‐risk
group
significantly
higher
than
those
healthy
subjects,
similar
also
found
left
insula
(degree:
.004;
betweenness:
.005;
age‐by‐group
interaction,
.038)
hippocampus
.003;
.003).
case–control
classifier
achieved
cross‐validation
accuracy
78.4%.
Conclusions
Our
findings
abnormal
organization
DMN
VN
advance
mechanistic
understanding
Neuroimaging
segregation
SFG
altered
centrality
broader
limbic
systems
used
target
interventions
tailored
mitigate
at‐risk
youth.
World Psychiatry,
Год журнала:
2024,
Номер
23(3), С. 432 - 437
Опубликована: Сен. 16, 2024
Children
who
have
a
parent
with
psychotic
disorder
present
an
increased
risk
of
developing
psychosis.
It
is
unclear
to
date,
however,
what
proportion
all
psychosis
cases
in
the
population
are
captured
by
familial
high‐risk
for
(FHR‐P)
approach.
This
essential
information
prevention
research
and
health
service
planning,
as
it
tells
us
total
that
this
approach
would
prevent
if
effective
intervention
were
developed.
Through
prospective
cohort
study
including
individuals
born
Finland
between
January
1,
1987
December
31,
1992,
we
examined
absolute
FHR‐P
transdiagnostic
(TDFR‐P)
based
on
parental
inpatient
hospitalization
any
mental
disorder.
Outcomes
non‐affective
(ICD‐10:
F20‐F29)
schizophrenia
F20)
identified
index
children
up
2016.
Of
(N=368,937),
1.5%
(N=5,544)
met
criteria
10.3%
(N=38,040)
TDFR‐P
criteria.
By
endpoint,
1.9%
(N=6,966)
had
been
diagnosed
0.5%
(N=1,846)
schizophrenia.
In
terms
sensitivity,
children,
5.2%
(N=355)
20.6%
(N=1,413)
approaches.
The
was
6.4%
those
FHR‐P,
3.7%
TDFR‐P.
There
notable
variation
sensitivity
age
at
which
FHR‐P/TDFR‐P
determined.
psychosis,
relatively
time
invariant.
These
metrics
inform
strategies
requiring
pragmatic
decision‐making.