Standards in Genomic Sciences, Год журнала: 2015, Номер 10(1)
Опубликована: Окт. 24, 2015
Propionibacterium freudenreichii subsp. DSM 20271(T) is the type strain of species that has a long history safe use in production dairy products and B12 vitamin. P. genus which contains Gram-positive, non-motile non-sporeforming bacteria with high G + C content. We describe genome consisting 2,649,166 bp chromosome containing 2320 protein-coding genes 50 RNA-only encoding genes.
Язык: Английский
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Год журнала: 2021, Номер 71(10)
Опубликована: Окт. 20, 2021
After the International Committee on Systematics of Prokaryotes (ICSP) had voted to include rank phylum in rules Code Nomenclature (ICNP), and following publication decision IJSEM, we here present names formal descriptions 42 phyla effect valid their names, based genera as nomenclatural types.
Язык: Английский
Процитировано
726
Cell Host & Microbe, Год журнала: 2013, Номер 14(6), С. 631 - 640
Опубликована: Дек. 1, 2013
Язык: Английский
Процитировано
321
Frontiers in Microbiology, Год журнала: 2015, Номер 6
Опубликована: Окт. 9, 2015
In disease-suppressive soils, plants are protected from infections by specific root pathogens due to the antagonistic activities of soil and rhizosphere microorganisms. For most however, microorganisms mechanisms involved in pathogen control largely unknown. Our recent studies identified Actinobacteria as dynamic phylum a suppressive fungal Rhizoctonia solani. Here we isolated characterized 300 isolates rhizospheric Rhizoctonia-suppressive soil. Streptomyces species were abundant, representing approximately 70% isolates. renowned for production an exceptionally large number secondary metabolites, including volatile organic compounds (VOCs). VOC profiling 12 representative SPME-GC-MS allowed more refined phylogenetic delineation than sequencing 16S rRNA house-keeping genes atpD recA only. VOCs several inhibited hyphal growth R. solani significantly enhanced plant shoot biomass. Coupling profiles with their effects on growth, pointed potentially antifungal activity. Subsequent assays five synthetic analogs showed that methyl 2-methylpentanoate, 1,3,5-trichloro-2-methoxy benzene mixture have conclusion, our results point potential role VOC-producing disease soils show can be used complementary identification tool construct strain-specific metabolic signatures.
Язык: Английский
Процитировано
219
Journal of Applied Microbiology, Год журнала: 2019, Номер 128(3), С. 630 - 657
Опубликована: Июль 16, 2019
The prevalence of multidrug-resistant microbial pathogens due to the continued misuse and overuse antibiotics in agriculture medicine is raising prospect a return preantibiotic days at time diminishing numbers drug leads. good news that an increased understanding nature extent diversity natural habitats coupled with application new technologies microbiology chemistry opening up strategies search for specialized products therapeutic properties. This review explores premise harsh environmental conditions extreme biomes, notably deserts, permafrost soils deep-sea sediments select micro-organisms, especially actinobacteria, cyanobacteria fungi, potential synthesize druggable molecules. There evidence over past decade micro-organisms adapted life are rich source metabolites. Extreme by their very tend be fragile hence there need conserve those known hot-spots novel gifted needed drive discovery campaigns innovative biotechnology. also provides overview microbial-derived molecules biological activities focusing on period from 2010 until 2018, this 186 structures were isolated 129 representatives taxa recovered habitats.
Язык: Английский
Процитировано
156
Proceedings of the National Academy of Sciences, Год журнала: 2017, Номер 114(44)
Опубликована: Окт. 3, 2017
Significance Microbial cells are widespread in diverse deep subseafloor environments; however, the viability, growth, and ecophysiology of these low-abundance organisms poorly understood. Using single-cell–targeted stable isotope probing incubations combined with nanometer-scale secondary ion mass spectrometry, we measured metabolic activity generation times thermally adapted microorganisms within Miocene-aged coal shale bed samples collected from 2 km below seafloor during Integrated Ocean Drilling Program Expedition 337. Microorganisms were capable metabolizing methylated substrates, including methylamine methanol, when incubated at their situ temperature 45 °C, but had exceedingly slow biomass ranging less than a year to hundreds years as by passive tracer deuterated water.
Язык: Английский
Процитировано
103
Antonie van Leeuwenhoek, Год журнала: 2018, Номер 111(8), С. 1315 - 1332
Опубликована: Май 2, 2018
Язык: Английский
Процитировано
88
BMC Microbiology, Год журнала: 2019, Номер 19(1)
Опубликована: Фев. 13, 2019
Colon cancer is the third most commonly diagnosed worldwide, with a commensurately high mortality rate. The search for novel antioxidants and specific anticancer agents which may inhibit, delay or reverse development of colon thus an area great interest; Streptomyces bacteria have been demonstrated to be source such agents. extract from sp. MUM265— strain was isolated identified Kuala Selangor mangrove forest, Selangor, Malaysia— analyzed found exhibit antioxidant properties as via metal-chelating ability well superoxide anion, DPPH ABTS radical scavenging activities. This study also showed that MUM265 cytotoxicity against cells evidenced by reduced cell viability Caco-2 line. Treatment induced depolarization mitochondrial membrane potential accumulation subG1 in cycle analysis, suggesting exerted apoptosis-inducing effects on cells. These findings indicate derived represents valuable bioresource bioactive compounds future chemopreventive agents, particular promise suggested treatment cancer.
Язык: Английский
Процитировано
83
Springer eBooks, Год журнала: 2014, Номер unknown, С. 103 - 203
Опубликована: Янв. 1, 2014
Язык: Английский
Процитировано
95
BMC Genomics, Год журнала: 2015, Номер 16(1)
Опубликована: Фев. 4, 2015
Members of the bacterial genus Arthrobacter are both readily cultured and commonly identified in Antarctic soil communities. Currently, relatively little is known about physiological traits that allow these bacteria to survive harsh environment. The aim this study investigate if strains owe their resilience substantial genomic changes compared spp. isolated from temperate environments.
Язык: Английский
Процитировано
84
BMC Microbiology, Год журнала: 2013, Номер 13(1), С. 145 - 145
Опубликована: Янв. 1, 2013
Andaman and Nicobar Islands situated in the eastern part of Bay Bengal are one distinguished biodiversity hotspot. Even though number studies carried out on marine flora fauna, actinobacteria from meager. The aim present study was to screen for their characterization identify potential sources industrial pharmaceutical byproducts. A total 26 actinobacterial strains were isolated sediments collected various sites Port Blair where no collection has been characterized previously. Isolates categorized under genera: Saccharopolyspora, Streptomyces, Nocardiopsis, Streptoverticillium, Microtetraspora, Actinopolyspora, Actinokineospora Dactylosporangium. Majority isolates found produce industrially important enzymes such as amylase, protease, gelatinase, lipase, DNase, cellulase, urease phosphatase, also exhibited substantial antibacterial activity against human pathogens. 77% significant hemolytic activity. Among isolates, three (NIOT-VKKMA02, NIOT-VKKMA22 NIOT-VKKMA26) generate appreciable extent surfactant, cellulase protease enzyme. NIOT-VKKMA02 produced surfactant using kerosene carbon source emulsified upto E24–63.6%. Moreover, NIOT-VKKMA02, NIOT-VKKMA26 synthesized 13.27 U/ml, 9.85 U/ml 8.03 amylase; 7.75 5.01 2.08 11.34 6.89 3.51 enzyme, respectively. High diversity this work including undescribed species not previously reported emerald Islands, Streptomyces griseus, venezuelae Saccharopolyspora salina. enhanced salt, pH temperature tolerance along with capacity secrete commercially valuable primary secondary metabolites emerges an attractive feature these organisms. These results first time expand scope functionally characterize novel molecules commercial interest.
Язык: Английский
Процитировано
83