Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 DOI Creative Commons
Soumyalekshmi Nair, Estefanía Nova‐Lamperti, Gonzalo Labarca

и другие.

Journal of Translational Medicine, Год журнала: 2023, Номер 21(1)

Опубликована: Окт. 10, 2023

Abstract COVID-19 continues to affect an unprecedented number of people with the emergence new variants posing a serious challenge global health. There is expansion knowledge in understanding pathogenesis Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and impact on multiple organs. In addition, growing evidence reports that different organs persists long after recovery phase disease, leading long-term consequences COVID-19. These involve pulmonary as well extra-pulmonary sequelae disease. Noteably, recent research has shown potential association between change molecular cargo extracellular vesicles (EVs). EVs are released cells play important role cell communication transfer bioactive molecules cells. Emerging shows strong link their cargo, regulation metabolism health This review focuses current about pathogenesis, future implications tools for biomarker therapeutic development possible effects

Язык: Английский

Comparative analysis of the minimal information for studies of extracellular vesicles guidelines: Advancements and implications for extracellular vesicle research DOI Creative Commons

Elisavet Maria Vaiaki,

Marco Falasca

Seminars in Cancer Biology, Год журнала: 2024, Номер 101, С. 12 - 24

Опубликована: Апрель 23, 2024

In 2014, the International Society for Extracellular Vesicles (ISEV) introduced Minimal Information Studies of (MISEV) guidelines to establish standards extracellular vesicle (EV) research. These aimed enhance reliability and reproducibility, addressing expanding field EV science. EVs, membrane-bound particles released by cells, play crucial roles in intercellular communication are potential biomarkers various conditions. Over years, landscape witnessed a surge publications, emphasizing their cancer immune modulation. response, MISEV underwent evolution, leading MISEV2018 update. This version, generated through community outreach, provided comprehensive framework research methodologies, separation, characterization, reporting standards, engagement. The reflected responsiveness feedback, acknowledging evolving landscape. served as testament commitment scientific rigorous collective discernment experts. present article compares previous with its 2023 counterpart, highlighting advancements, changes, impacts on standardization. build upon 2018 principles, offering new recommendations emerging areas. comparative exploration contributes understanding transformative journey research, MISEV's pivotal role community's adaptability challenges.

Язык: Английский

Процитировано

14

Proteomics provides insights into the theranostic potential of extracellular vesicles DOI
Morteza Abyadeh, Mehdi Alikhani, Mehdi Mirzaei

и другие.

Advances in protein chemistry and structural biology, Год журнала: 2023, Номер unknown, С. 101 - 133

Опубликована: Дек. 1, 2023

Язык: Английский

Процитировано

5

Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 DOI Creative Commons
Soumyalekshmi Nair, Estefanía Nova‐Lamperti, Gonzalo Labarca

и другие.

Journal of Translational Medicine, Год журнала: 2023, Номер 21(1)

Опубликована: Окт. 10, 2023

Abstract COVID-19 continues to affect an unprecedented number of people with the emergence new variants posing a serious challenge global health. There is expansion knowledge in understanding pathogenesis Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and impact on multiple organs. In addition, growing evidence reports that different organs persists long after recovery phase disease, leading long-term consequences COVID-19. These involve pulmonary as well extra-pulmonary sequelae disease. Noteably, recent research has shown potential association between change molecular cargo extracellular vesicles (EVs). EVs are released cells play important role cell communication transfer bioactive molecules cells. Emerging shows strong link their cargo, regulation metabolism health This review focuses current about pathogenesis, future implications tools for biomarker therapeutic development possible effects

Язык: Английский

Процитировано

4