International journal of basic science in medicine, Год журнала: 2024, Номер 9(1), С. 36 - 44
Опубликована: Март 27, 2024
The spectrum of diseases caused by intracellular bacterial pathogens (IBPs) is broad, ranging from life-threatening conditions such as tuberculosis to other infectious-transmitted diseases. Conventional antibiotic treatment faces challenges due resistance, host cell toxicity, and limited drug penetration. Despite the excellent ability these perilous modulate biology, localize in, multiply through targeting key virulence factors, brings about auspicious maneuvers combat pathogenic alleviate their significant global burden. Modulation identification molecules, pathways, responses are initial steps targeted therapy, varying disease disease. This article explores cutting-edge advancements in therapy approaches. Innovations nanoparticlebased delivery systems, phage immunomodulation, gene editing, which hold a promising future for overcoming limitations traditional treatment, also discussed. Efficient optimizations, inch-perfect distribution retention therapeutic agents some determining factors success pathogens. presents novel application wherein filamentous phages loaded targets nanocarriers purposes. present faced researchers, along with directions this field medical science, outlined. Overall, scope involves various strategies involved modulations, our current
Язык: Английский