Nature of Genomic Architecture: A Topological Model of Genome

Опубликована: Янв. 1, 2023

Our present understanding of genomic architecture is based on incremental addition the manner in which genes are expressed. At present, there no theoretical model architecture. This largely because genomics focused how genome operates and not has evolved. In absence any such ontological perspective, cannot be formalized. chapter seeks to fill this lacuna. A topological formalism involuted manifold outlined chapter. It formalize long-range influences involved gene expressions by class operators called involutions. describes a possible course evolution using involutions as representing forces natural selection.

Язык: Английский

Understanding the Code of Life: Holistic Conceptual Modeling of the Genome

Опубликована: Дек. 22, 2022

Las fructíferas discusiones y los resultados derivados de proyectos INNEST2021 /57, MICIN/AEI/10.13039/501100011033, PID2021-123824OB-I00, CIPROM/2021/023 PDC2021- 121243-I00 han contribuido en gran medida a la calidad final este tesis.