Nose-on-Chip Nanobiosensors for Early Detection of Lung Cancer Breath Biomarkers
ACS Sensors,
Год журнала:
2024,
Номер
9(9), С. 4469 - 4494
Опубликована: Сен. 9, 2024
Lung
cancer
remains
a
global
health
concern,
demanding
the
development
of
noninvasive,
prompt,
selective,
and
point-of-care
diagnostic
tools.
Correspondingly,
breath
analysis
using
nanobiosensors
has
emerged
as
promising
noninvasive
nose-on-chip
technique
for
early
detection
lung
through
monitoring
diversified
biomarkers
such
volatile
organic
compounds/gases
in
exhaled
breath.
This
comprehensive
review
summarizes
state-of-the-art
breath-based
diagnosis
employing
chemiresistive-module
supported
by
theoretical
findings.
It
unveils
fundamental
mechanisms
biological
basis
biomarker
generation
associated
with
cancer,
technological
advancements,
clinical
implementation
nanobiosensor-based
analysis.
explores
merits,
challenges,
potential
alternate
solutions
implementing
these
settings,
including
standardization,
biocompatibility/toxicity
analysis,
green
sustainable
technologies,
life-cycle
assessment,
scheming
regulatory
modalities.
highlights
nanobiosensors'
role
facilitating
precise,
real-time,
on-site
leading
to
improved
patient
outcomes,
enhanced
management,
remote
personalized
monitoring.
Additionally,
integrating
biosensors
artificial
intelligence,
machine
learning,
Internet-of-things,
bioinformatics,
omics
technologies
is
discussed,
providing
insights
into
prospects
intelligent
sniffing
nanobiosensors.
Overall,
this
consolidates
knowledge
on
breathomic
biosensor-based
screening,
shedding
light
its
significance
applications
advancing
medical
diagnostics
reduce
burden
hospitals
save
human
lives.
Язык: Английский
Plasmonic-enabled nanostructures for designing the next generation of silicon photodetectors: Trends, engineering and opportunities
Surfaces and Interfaces,
Год журнала:
2024,
Номер
48, С. 104334 - 104334
Опубликована: Апрель 15, 2024
Язык: Английский
Synergizing Nanomaterials and Artificial Intelligence in Advanced Optical Biosensors for Precision Antimicrobial Resistance Diagnosis
ACS Synthetic Biology,
Год журнала:
2024,
Номер
13(6), С. 1600 - 1620
Опубликована: Июнь 6, 2024
Antimicrobial
resistance
(AMR)
poses
a
critical
global
One
Health
concern,
ensuing
from
unintentional
and
continuous
exposure
to
antibiotics,
as
well
challenges
in
accurate
contagion
diagnostics.
Addressing
AMR
requires
strategic
approach
that
emphasizes
early
stage
prevention
through
screening
clinical,
environmental,
farming,
livestock
settings
identify
nonvulnerable
antimicrobial
agents
the
associated
genes.
Conventional
diagnostics,
like
antibiotic
susceptibility
testing,
possess
drawbacks,
including
high
costs,
time-consuming
processes,
significant
manpower
requirements,
underscoring
need
for
intelligent,
prompt,
on-site
diagnostic
techniques.
Nanoenabled
artificial
intelligence
(AI)-supported
smart
optical
biosensors
present
potential
solution
by
facilitating
rapid
point-of-care
detection
with
real-time,
sensitive,
portable
capabilities.
This
Review
comprehensively
explores
various
types
of
nanobiosensors,
such
surface
plasmon
resonance
sensors,
whispering-gallery
mode
coherence
tomography,
interference
reflection
imaging
surface-enhanced
Raman
spectroscopy,
fluorescence
microring
tweezer
biosensors,
By
harnessing
unique
advantages
these
nanoenabled
revolutionary
paradigm
shift
diagnostics
can
be
achieved,
characterized
results,
sensitivity,
portability,
integration
Internet-of-Things
(IoT)
technologies.
Moreover,
enable
personalized
monitoring
detection,
significantly
reducing
turnaround
time
eliminating
human
resources
needed
sample
preservation
transportation.
Their
holistic
environmental
surveillance
further
enhances
capabilities
diverse
settings,
leading
improved
modern-age
healthcare
practices
more
effective
management
treatments.
Embracing
advanced
tools
promises
bolster
capacity
combat
safeguard
Health.
Язык: Английский
Photonics-powered augmented reality skin electronics for proactive healthcare: multifaceted opportunities
Microchimica Acta,
Год журнала:
2024,
Номер
191(5)
Опубликована: Апрель 8, 2024
Язык: Английский
Fate of Sniff-the-Diseases Through Nanomaterials-Supported Optical Biochip Sensors
ECS Journal of Solid State Science and Technology,
Год журнала:
2024,
Номер
13(4), С. 047004 - 047004
Опубликована: Апрель 1, 2024
Early
diagnosis
through
noninvasive
tools
is
a
cornerstone
in
the
realm
of
personalized
and
medical
healthcare,
averting
direct/indirect
infection
transmission
directly
influencing
treatment
outcomes
patient
survival
rates.
In
this
context,
optical
biochip
breathomic
sensors
integrated
with
nanomaterials,
microfluidics,
artificial
intelligence
exhibit
potential
to
design
next-generation
intelligent
diagnostics.
This
cutting-edge
tool
offers
variety
advantages,
including
being
economical,
compact,
smart,
point
care,
highly
sensitive,
noninvasive.
makes
it
an
ideal
avenue
for
screening,
diagnosing,
prognosing
various
high-risk
diseases/disorders
by
detecting
associated
breath
biomarkers.
The
underlying
detection
mechanism
relies
on
interaction
biomarkers
sensors,
which
causes
modulations
fundamental
attributes,
such
as
surface
plasmon
resonance,
fluorescence,
reflectance,
absorption,
emission,
phosphorescence,
refractive
index.
Despite
these
remarkable
commercial
development
faces
challenges,
insufficient
support
from
clinical
trials,
concerns
about
cross-sensitivity,
challenges
related
production
scalability,
validation
issues,
regulatory
compliance,
contrasts
conventional
perspective
article
sheds
light
state
disease
diagnosis,
addresses
proposes
alternative
solutions,
explores
future
avenues
revolutionize
healthcare
Язык: Английский
Irrigation intelligence—enabling a cloud-based Internet of Things approach for enhanced water management in agriculture
Environmental Monitoring and Assessment,
Год журнала:
2024,
Номер
196(5)
Опубликована: Апрель 9, 2024
Язык: Английский
Nanophotonic catheters: A lens into the body for biosensing and biomedical imaging
Applied Materials Today,
Год журнала:
2024,
Номер
38, С. 102229 - 102229
Опубликована: Май 21, 2024
Язык: Английский
Nanoparticle-Based Biomarkers for Neurological Disorders
Nanotechnology in the life sciences,
Год журнала:
2025,
Номер
unknown, С. 183 - 202
Опубликована: Янв. 1, 2025
Язык: Английский
Nanosensors Based on Breathomics for Human Disease Diagnosis: a New Frontier in Personalized Healthcare
BioNanoScience,
Год журнала:
2025,
Номер
15(2)
Опубликована: Март 14, 2025
Язык: Английский
Box-Behnken Response Surface Design for the Optimization of a High-Performance Electrochemical Dopamine Sensor Based on Novel Nano-Ag Doped Matériaux Institut Lavoisier Metal-Organic Framework 101 (MIL-101-Cr) Composite Modified Glassy Carbon Electrode
Journal of The Electrochemical Society,
Год журнала:
2024,
Номер
171(9), С. 097511 - 097511
Опубликована: Сен. 2, 2024
The
combination
of
metal-organic
frameworks
(MOFs)
and
metal
nanoparticles
offers
great
prospects
for
improving
the
electrochemical
properties
sensors.
In
this
paper,
silver
(Ag)
nanoparticle-doped
framework
(MIL-101)
composites
(Ag-MIL-101)
were
prepared
by
ultrasonic
treatment
MIL-101
reduction
precursor
(AgNO3)
within
material.
X-ray
diffraction
patterns
confirmed
formation
Ag-MIL-101(Cr).
resulting
material
was
used
to
construct
a
new
sensor
reliable
detection
dopamine.
response
developed
toward
dopamine
evaluated
using
differential
pulse
voltammetry.
A
Box-Behnken
design
performed,
surface
methodology
study
influence
different
parameters
on
detection.
modified
electrode
linear
in
range
from
0.02
μM
10
μM,
limit
(S/N
=
3).
Additionally,
it
showed
high
selectivity
presence
urea,
uric
acid,
ascorbic
L-arginine.
Due
its
low
cost,
easy
process,
performance,
Ag-MIL-101/GCE
can
be
good
candidate
fabrication
non-enzymatic
sensor.
Язык: Английский