Harmful Algae,
Год журнала:
2023,
Номер
127, С. 102466 - 102466
Опубликована: Июнь 2, 2023
Cyanobacteria
harmful
algal
blooms
produce
many
toxic
secondary
metabolites
called
cyanotoxins.
The
most
studied
group
of
cyanotoxins
are
microcystins
(MC),
with
over
300
congeners
reported.
MC-LR
is
the
congener
because
its
abundance
and
toxicity.
Recent
toxicology
studies
suggest
that
more
hydrophobic
MC
such
as
MC-LA,
MC-LF,
MC-LW
may
be
less
abundant
but
up
to
seven
times
than
MC-LR,
whereas,
MC-RR's
toxicity
only
one-fifth
MC-LR.
Hence,
understanding
environmental
stressors
change
profile
critical
assessing
negative
impact
on
human
health.
A
two-year
field
experimental
study
investigated
seasonal
spatial
changes
profiles
in
western
basin
Lake
Erie.
Both
showed
nitrogen
enrichment
favored
production
nitrogen-rich
MC-RR
(C49H75N13O12).
depletion
low-nitrogen
MC-LA
(C46H67N7O12).
(a
medium
N
level,
C49H75N10O12)
accounted
for
∼30%
50%
total
concentration
was
stable
across
concentrations.
Using
relative
concentrations
each
congener,
both
LC-MS/MS
ELISA
overestimated
early
bloom
(July)
underestimated
it
late
(September).
On
24
July
2019,
highly
MC-LF
were
detected
at
nearshore
stations
exceeding
drinking
water
standards.
This
demonstrated
toxic,
high
dominated
under
nitrogen-replete
conditions
season,
whereas
nitrogen-limited
later
season.
Marine Drugs,
Год журнала:
2019,
Номер
17(6), С. 320 - 320
Опубликована: Май 30, 2019
Cyanobacteria
are
photosynthetic
microorganisms
that
colonize
diverse
environments
worldwide,
ranging
from
ocean
to
freshwaters,
soils,
and
extreme
environments.
Their
adaptation
capacities
the
diversity
of
natural
products
they
synthesize,
support
cyanobacterial
success
in
colonization
their
respective
ecological
niches.
Although
cyanobacteria
well-known
for
toxin
production
relative
deleterious
consequences,
also
produce
a
large
variety
molecules
exhibit
beneficial
properties
with
high
potential
various
fields
(e.g.,
synthetic
analog
dolastatin
10
is
used
against
Hodgkin's
lymphoma).
The
present
review
focuses
on
activities
described
so
far.
Based
an
analysis
670
papers,
it
appears
more
than
90
genera
have
been
observed
compounds
potentially
which
most
them
belong
orders
Oscillatoriales,
Nostocales,
Chroococcales,
Synechococcales.
rest
(i.e.,
Pleurocapsales,
Chroococcidiopsales,
Gloeobacterales)
remain
poorly
explored
terms
molecular
bioactivity.
metabolites
possessing
bioactivities
different
chemical
classes
(alkaloids,
depsipeptides,
lipopeptides,
macrolides/lactones,
peptides,
terpenes,
polysaccharides,
lipids,
polyketides,
others)
14
major
kinds
However,
no
direct
relationship
between
class
bioactivity
these
has
demonstrated.
We
further
selected
specifically
47
molecule
families
according
uses
pharmacology,
cosmetology,
agriculture,
or
other
specific
interest.
With
this
up-to-date
review,
we
attempt
new
perspectives
rational
discovery
novel
Environmental Science & Technology,
Год журнала:
2020,
Номер
55(1), С. 44 - 64
Опубликована: Дек. 18, 2020
The
global
expansion
of
harmful
cyanobacterial
blooms
(CyanoHABs)
poses
an
increasing
threat
to
public
health.
CyanoHABs
are
characterized
by
the
production
toxic
metabolites
known
as
cyanotoxins.
Human
exposure
cyanotoxins
is
challenging
forecast,
and
perhaps
least
understood
route
via
inhalation.
While
aerosolization
toxins
from
marine
algal
(HABs)
has
been
well
documented,
in
freshwater
systems
remains
understudied.
In
recent
years,
spray
aerosol
(SA)
produced
airshed
Laurentian
Great
Lakes
(United
States
Canada)
characterized,
suggesting
that
may
impact
atmospheric
loading
more
than
previously
understood.
Therefore,
further
investigation
regarding
on
human
respiratory
health
warranted.
This
review
examines
current
research
incorporation
cells
into
SA
aquatic
ecosystems
which
experience
HABs.
We
present
overview
cyanotoxin
fate
environment,
biological
SA,
existing
data
relevant
collection
methods,
adverse
outcomes
associated
with
Environments,
Год журнала:
2020,
Номер
7(2), С. 13 - 13
Опубликована: Фев. 12, 2020
Continual
increases
in
the
human
population
and
growing
concerns
related
to
energy
crisis,
food
security,
disease
outbreaks,
global
warming,
other
environmental
issues
require
a
sustainable
solution
from
nature.
One
of
promising
resources
is
cyanobacteria,
also
known
as
blue-green
algae.
They
simple
ingredients
grow
possess
relatively
genome.
Cyanobacteria
are
produce
wide
variety
bioactive
compounds.
In
addition,
cyanobacteria’s
remarkable
growth
rate
enables
its
potential
use
range
applications
fields
bioenergy,
biotechnology,
natural
products,
medicine,
agriculture,
environment.
this
review,
we
have
summarized
cyanobacteria
different
areas
science
development,
especially
their
producing
biofuels
valuable
co-products.
We
discussed
challenges
that
hinder
such
development
at
an
industrial
level
ways
overcome
obstacles.
Toxins,
Год журнала:
2019,
Номер
11(9), С. 530 - 530
Опубликована: Сен. 12, 2019
The
widespread
distribution
of
cyanobacteria
in
the
aquatic
environment
is
increasing
risk
water
pollution
caused
by
cyanotoxins,
which
poses
a
serious
threat
to
human
health.
However,
structural
characterization,
and
identification
techniques
cyanotoxins
have
not
been
comprehensively
reviewed
previous
studies.
This
paper
aims
elaborate
existing
information
systematically
on
diversity
identify
valuable
research
avenues.
According
chemical
structure,
are
mainly
classified
into
cyclic
peptides,
alkaloids,
lipopeptides,
nonprotein
amino
acids
lipoglycans.
In
terms
global
distribution,
amount
unbalanced
different
areas.
more
obviously
found
many
developed
countries
than
that
undeveloped
countries.
Moreover,
has
promoted
development
detection
technology.
Many
emerging
methods
detect
environment.
communication
provides
comprehensive
review
technology
was
discussed.
detailed
will
be
resource
for
identifying
various
types
threaten
ability
accurately
specific
an
obvious
essential
aspect
cyanobacterial
research.
Water Research,
Год журнала:
2020,
Номер
188, С. 116543 - 116543
Опубликована: Окт. 22, 2020
This
review
compiles
recent
advances
and
challenges
in
the
photocatalytic
treatment
of
natural
water
by
analyzing
remediation
cyanotoxins.
The
frames
need
based
on
occurrence,
geographical
distribution,
legislation
cyanotoxins
drinking
while
highlighting
underestimated
global
risk
Next,
fundamental
principles
for
remediating
complex
degradation
pathway
most
widespread
are
presented.
state-of-the-art
processes
critically
discussed,
especially
modification
strategies
involving
TiO2
primary
operational
conditions
that
determine
scalability
integration
reactors.
relevance
light
sources
delivery
shown,
with
emphasis
novel
biomimicry
materials
design.
Thereafter,
seldomly-addressed
role
water-matrix
components
is
thoroughly
explored
including
organic
matter
inorganic
species
to
provide
future
directions
designing
highly
efficient
scalable
