Carotenoids for Antiaging: Nutraceutical, Pharmaceutical, and Cosmeceutical Applications DOI Creative Commons
Mariia Shanaida, Olha Мykhailenko, Roman Lysiuk

и другие.

Pharmaceuticals, Год журнала: 2025, Номер 18(3), С. 403 - 403

Опубликована: Март 13, 2025

Background: Carotenoids are bioactive tetraterpenoid C40 pigments that actively synthesized by plants, bacteria, and fungi. Compounds such as α-carotene, β-carotene, lycopene, lutein, astaxanthin, β-cryptoxanthin, fucoxanthin, zeaxanthin have attracted increasing attention for their antiaging properties. They exhibit antioxidant, neuroprotective, anti-inflammatory properties, contributing to the prevention treatment of age-related diseases. Objectives: The aim this study was comprehensively analyze pharmacological potential biological mechanisms carotenoids associated with disorders evaluate application in nutraceuticals, pharmaceuticals, cosmeceuticals. Methods: A systematic review studies published over past two decades conducted using databases PubMed, Scopus, Web Science. selection criteria included clinical, silico, vivo, vitro investigating therapeutic effects carotenoids. Results: demonstrate a variety health benefits, including macular degeneration, cancer, cognitive decline, metabolic disorders, skin aging. Their role nutraceuticals is well supported ability modulate oxidative stress inflammatory pathways. In show promising results formulations targeting neurodegenerative diseases disorders. cosmeceuticals, they improve protecting it against UV radiation damage. However, bioavailability, optimal dosages, toxicity, interactions other compounds remain critical factors maximize efficacy still require careful evaluation scientists. Conclusions: interventions applications fields. Further research needed optimize formulas, confirm long-term safety effectiveness, especially aging population.

Язык: Английский

Carotenoids for Antiaging: Nutraceutical, Pharmaceutical, and Cosmeceutical Applications DOI Creative Commons
Mariia Shanaida, Olha Мykhailenko, Roman Lysiuk

и другие.

Pharmaceuticals, Год журнала: 2025, Номер 18(3), С. 403 - 403

Опубликована: Март 13, 2025

Background: Carotenoids are bioactive tetraterpenoid C40 pigments that actively synthesized by plants, bacteria, and fungi. Compounds such as α-carotene, β-carotene, lycopene, lutein, astaxanthin, β-cryptoxanthin, fucoxanthin, zeaxanthin have attracted increasing attention for their antiaging properties. They exhibit antioxidant, neuroprotective, anti-inflammatory properties, contributing to the prevention treatment of age-related diseases. Objectives: The aim this study was comprehensively analyze pharmacological potential biological mechanisms carotenoids associated with disorders evaluate application in nutraceuticals, pharmaceuticals, cosmeceuticals. Methods: A systematic review studies published over past two decades conducted using databases PubMed, Scopus, Web Science. selection criteria included clinical, silico, vivo, vitro investigating therapeutic effects carotenoids. Results: demonstrate a variety health benefits, including macular degeneration, cancer, cognitive decline, metabolic disorders, skin aging. Their role nutraceuticals is well supported ability modulate oxidative stress inflammatory pathways. In show promising results formulations targeting neurodegenerative diseases disorders. cosmeceuticals, they improve protecting it against UV radiation damage. However, bioavailability, optimal dosages, toxicity, interactions other compounds remain critical factors maximize efficacy still require careful evaluation scientists. Conclusions: interventions applications fields. Further research needed optimize formulas, confirm long-term safety effectiveness, especially aging population.

Язык: Английский

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