Journal of Biochemical and Molecular Toxicology, Год журнала: 2025, Номер 39(5)

Опубликована: Апрель 24, 2025

ABSTRACT Modern advancements in medicine include developing targeted drug delivery systems the medical field, which are designed to unravel potential of therapeutic products and overcome barriers effectiveness current approaches. Various nanopolymer carrier have been introduced this regard, simple characteristics extracellular vesicles drawn special attention their application as an effective tool. Exosomes very similar transport a lipid‐biomembrane covering aqueous core. They also contain both hydrophilic lipophilic substances deliver cargo desired targets. These properties enable exosomes some limitations liposomes. can easily diffuse into body fluids remain bloodstream for long time, crossing physiological entering cells. Exosomes, large volume biomolecules, do not stimulate immune responses accumulate liver or lungs instead target tissues. Recent regenerative enabled scientists utilize extracted from mesenchymal stem cells (MSCs), possess significant abilities, treating various diseases. The contents these crucial diagnosis treatment, they influence disease progression. Numerous vitro studies confirmed safety, effectiveness, promise conditions such cancer, neurodegenerative disorders, cardiovascular issues, orthopedic ailments. This article explores MSC‐derived outlines essential procedures preparation.

Язык: Английский