Methods in molecular biology, Год журнала: 2023, Номер unknown, С. 213 - 250
Опубликована: Янв. 1, 2023
Язык: Английский
Clinical and Translational Discovery, Год журнала: 2024, Номер 4(5)
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
0
Aging and Disease, Год журнала: 2024, Номер unknown, С. 0 - 0
Опубликована: Янв. 1, 2024
Angina pectoris (AP), a clinical syndrome characterized by paroxysmal chest pain, is caused insufficient blood supply to the coronary arteries and sudden temporary myocardial ischemia hypoxia. Long-term AP typically induces other cardiovascular events, including infarction heart failure, posing serious threat patient safety. However, AP's complex pathological mechanisms developmental processes introduce significant challenges in rapid diagnosis accurate treatment of its different subtypes, stable angina (SAP), unstable (UAP), variant (VAP). Omics research has contributed significantly revealing various diseases with development high-throughput sequencing approaches. The application multi-omics approaches effectively interprets systematic information on from perspective genes, RNAs, proteins, metabolites. Integrating introduces novel avenues for identifying biomarkers distinguish subtypes. This study reviewed articles related elaborate progress (including genomics, transcriptomics, proteomics, metabolomics), summarized their applications screening employed discriminate multiple delineated integration methods Finally, we discussed advantages disadvantages applying single-omics approach distinguishing diverse Our review demonstrated that technologies preferable quick precise three types, namely SAP, UAP, VAP.
Язык: Английский
Процитировано
0
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0
Journal of Molecular and Cellular Cardiology, Год журнала: 2024, Номер 199, С. 62 - 77
Опубликована: Дек. 27, 2024
Язык: Английский
Процитировано
0
Methods in molecular biology, Год журнала: 2023, Номер unknown, С. 213 - 250
Опубликована: Янв. 1, 2023
Язык: Английский
Процитировано
0