Anthracycline Cardiotoxicity in Adult Cancer Patients

JACC CardioOncology, Год журнала: 2024, Номер 6(5), С. 655 - 677

Опубликована: Сен. 17, 2024

Язык: Английский

---

Cardio-oncology: chances and challenges

Basic Research in Cardiology, Год журнала: 2024, Номер unknown

Опубликована: Сен. 30, 2024

Язык: Английский

---

Cardio-oncology: Emerging Concepts in Cardiovascular Sequelae of Cancer Therapies, Translational Research and Reverse Cardio-oncology

European Cardiology Review, Год журнала: 2025, Номер 20

Опубликована: Март 21, 2025

Cardio-oncology was established with the aim of defining primary and secondary prevention approaches through surveillance use tools to stratify diminish cardiovascular risk cancer patients. This branch medicine also contributes establishing a new field in translational for disease by focusing on interplay between heart disease. In this first article cardio-oncology section journal, we explore main concepts emerging anti-cancer therapies their plausible cardiotoxic effects will describe advances gaps knowledge, highlighting how is contributing cardiology. We speculate complex failure discuss an concept known as reverse cardio-oncology. present perspective that represents promising platform area research, allowing discovery novel pathways involved identification toxicities induced targeted therapies.

Язык: Английский

---

Anthracycline-induced cardiomyopathy: risk prediction, prevention and treatment

Nature Reviews Cardiology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 28, 2025

Язык: Английский

---

Serum Albumin–Creatinine Ratio and Anthracycline Cardiotoxicity in Patients with Cancer

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(5), С. 1741 - 1741

Опубликована: Март 5, 2025

Background: Several studies have suggested that the serum albumin-creatinine ratio (sACR) is a useful marker for early risk stratification of patients with cardiomyocyte injury. This study aims to evaluate relationship between sACR and anthracycline-related cardiotoxicity. Methods: included who had received anthracycline-based chemotherapy 2014 2023 undergone baseline follow-up echocardiography after treatment. The level was calculated using albumin creatinine values obtained before chemotherapy. definition cardiotoxicity based on criteria European Society Cardiology (ESC) ejection fraction American Echocardiography (ASE) diastolic dysfunction. were categorized into either high or low group cut-off value from receiver operating characteristic (ROC) curve analysis. Results: In total, 525 (159 males, 366 females) included. Multivariate analysis adjustment age, body mass index (BMI), cardiovascular disease, hemoglobin, anthracycline dose, gender showed (HR = 1.85% 95 CI 1.12 3.06 p 0.016), disease 1.97% 1.08 3.61 0.027), BMI 1.86% 3.10 0.017), age 1.02% 1.001 1.04 0.036) significantly associated an increased Conclusions: first show significant related use. Routine laboratory tests are conducted therapy can aid clinicians in identifying high-risk may require closer cardioprotective measures.

Язык: Английский

---

Insulin resistance and cancer: molecular links and clinical perspectives

Molecular and Cellular Biochemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 15, 2025

Язык: Английский

---

Anthracyclines, diastolic dysfunction and the road to heart failure in Cancer survivors: An untold story

Progress in Cardiovascular Diseases, Год журнала: 2024, Номер 86, С. 38 - 47

Опубликована: Июль 25, 2024

Язык: Английский

---