Effect of COVID-19 on Pregnancy and Neonate’s Vital Parameters: A Systematic Review

Journal of Pregnancy, Год журнала: 2023, Номер 2023, С. 1 - 21

Опубликована: Май 13, 2023

Background. COVID-19 is a new pandemic, which was declared by the World Health Organization in 2019 as threat to public health. According numerous reports, it can have negative consequences for pregnant women, labour, and neonates born infected mothers. The aim of this paper gather evidence present summary results studies concerning women their neonates. Methods. Articles from prestigious journals covering period 2020 February 2023, relevant review papers, original research articles PubMed were analysed. In order analyse available literature, Web Science, Scopus, databases used, search conducted using terms (“pregnancy,” “coronavirus,” “SARS-CoV-2,” “newborn”) PRISMA (Preferred Reporting Items Systemic Reviews Meta-Analysis) guidelines clinical trials. Meta-analyses systematic reviews (2022–2023) on symptoms, neonatal course, risk infection been summarized. Summary meta-analyses effect adverse reaction vaccination presented. Results. As result conducted, confirmed that most no serious signs observed, although isolated cases death related reported. Several authors called attention more severe course with obesity. It seemed vertical transmission mother child occurring. Nevertheless, information not clinching. condition mothers described normal; however, some papers reported deaths Conclusions. Due insufficient data, further necessary. Further follow-up are recommended, would make possible an assessment remote effects pregnancy vital parameters newborn.

Язык: Английский

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Protective role of macrophages from maternal–fetal interface in unvaccinated coronavirus disease 2019 pregnant women

Journal of Medical Virology, Год журнала: 2024, Номер 96(7)

Опубликована: Июль 1, 2024

Abstract Pregnant women represent a high‐risk population for Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) infection. The presence of SARS‐CoV‐2 has been reported in placenta from infected pregnant women, but whether the virus influences immune response remains unclear. We investigated properties maternal–fetal interface macrophages (MFMs) cohort unvaccinated who contracted coronavirus disease 2019 (COVID‐19) during their pregnancy. an infiltration CD163 + COVID‐19 19 whereas lymphoid compartment was not affected. Isolated MFMs exhibited nonpolarized activated signature ( NOS 2, IDO1 , IFNG TNF TGFB ) mainly second trimester pregnancy primed MFM to produce type I and III interferon (Wuhan δ strains), that were unable elicit this healthy women. also internalization by angiotensin‐converting enzyme 2‐dependent manner. Activation recall responses influenced fetal sex. Collectively, these findings support role local infection, provide basis protective placental immunity COVID‐19, highlight interest vaccination

Язык: Английский

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Retrospective Analysis of the Impact of SARS‐CoV‐2 (COVID‐19) on Pregnancy and Neonatal Outcomes

Journal of Pregnancy, Год журнала: 2024, Номер 2024(1)

Опубликована: Янв. 1, 2024

The novel coronavirus disease 2019 (COVID-19) was more devastating in people with comorbidities such as advanced age and immunodeficiency. Another group affected by COVID-19 pregnant women. Immunological changes during pregnancy conditions gestational diabetes pre-eclampsia that occur also have effects on the fetus. aim of this study to analyze PCR-proven infection fetus newborn.

Язык: Английский

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Pregnancy and COVID-19

Journal of Clinical Medicine, Год журнала: 2022, Номер 11(22), С. 6645 - 6645

Опубликована: Ноя. 9, 2022

Evidence indicates that SARS-CoV-2 infection increases the likelihood of adverse pregnancy outcomes. Modifications in circulatory, pulmonary, hormonal, and immunological pathways induced by render pregnant women as a high-risk group. A growing body research shows during is connected to number maternal complications, including pneumonia intensive care unit (ICU) hospitalization. Miscarriages, stillbirth, preterm labor, well pre-eclampsia intrauterine growth restriction are also among most often documented fetal implications, particularly expecting who have significant COVID-19 symptoms, affecting timing route delivery. Thus, prevention pharmacological treatment options should aim minimize aforementioned risks ameliorate maternal, obstetric fetal/neonatal

Язык: Английский

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Effect of SARS-CoV-2 infection in pregnancy on CD147, ACE2 and HLA-G expression

Placenta, Год журнала: 2023, Номер 132, С. 38 - 43

Опубликована: Янв. 5, 2023

Язык: Английский

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