Drugs, Год журнала: 2024, Номер 84(8), С. 909 - 932
Опубликована: Июль 2, 2024
Язык: Английский
Drugs, Год журнала: 2024, Номер 84(8), С. 909 - 932
Опубликована: Июль 2, 2024
Язык: Английский
American Journal of Speech-Language Pathology, Год журнала: 2025, Номер unknown, С. 1 - 15
Опубликована: Янв. 6, 2025
The caregiver burden of individuals with dysphagia is a major concern. Currently, assessment tools specifically designed for this population are lacking. present study aimed to translate the Caregiver Analysis Reported Experiences Swallowing Disorders (CARES) Questionnaire into Mandarin Chinese and evaluate its psychometric properties. This analyzed properties version CARES questionnaire using classical measurement theory Rasch model analysis. Classical theory: item-level content validity index ranged from .83 1.00, scale-level .93 .95. correlation coefficient between total scores, subscale scores questionnaire, Zarit Burden Interview was .82 .87 (p < .01). There were significant relationships dysphagia-specific perceived swallowing impairment (Eating Assessment Tool-10) diet restrictiveness (International Dysphagia Diet Standardisation Initiative Functional Scale). overall Cronbach's α .81. Item response unidimensional. item difficulty individual ability evenly distributed. reliability .96, person .79, separation 4.95, 1.93. demonstrates satisfactory can be utilized as specific tool evaluating informal dysphagia.
Язык: Английский
Процитировано
0Frontiers in Oncology, Год журнала: 2025, Номер 15
Опубликована: Фев. 7, 2025
Background Predictive models can identify patients at risk and thus enable personalized interventions. Despite the increasing number of prediction used to predict dysphagia after radiotherapy in with head neck cancer (HNC), there is still uncertainty about effectiveness these clinical practice quality applicability future studies. The aim this study was systematically evaluate analyze all predictive HNC radiotherapy. Methods PubMed, Cochrane Library, EMbase Web Science databases were searched from database establishment August 31, 2024. Data selected studies extracted using predefined tables modelling assessed PROBAST tool. Meta-analysis performance model performed “metafor” package R software. Results Twenty-five predicting included, covering a total 8,024 patients. Common predictors include mean dose pharyngeal constrictor muscles, treatment setting, tumor site. Of models, most constructed based on logistic regression, while only two machine learning methods. area under receiver operating characteristic curve (AUC) reported values for ranged 0.57 0.909, 13 having combined AUC value 0.78 (95% CI: 0.74-0.81). All showed high bias as by Conclusion Most published have good discrimination. However, considered assessments. Future should focus large sample size rigorously designed multicenter external validation improve reliability HNC. Systematic review registration https://www.crd.york.ac.uk/prospero , identifier CRD42024587252.
Язык: Английский
Процитировано
0Oral Surgery Oral Medicine Oral Pathology and Oral Radiology, Год журнала: 2025, Номер unknown
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0Journal of Oral Rehabilitation, Год журнала: 2025, Номер unknown
Опубликована: Фев. 27, 2025
ABSTRACT Objective As a common complication following particle therapy for head and neck cancer (HNC), dysphagia poses significant risks adverse outcomes patients. This study aims to investigate the efficacy of an evidence‐based combined regimen feeding management swallowing training on improving function, swallowing‐related quality life nutritional status in patients with dysphagia. Methods We conducted randomised parallel‐controlled trial at Shanghai Proton Heavy Ion Center from March 2023 October 2023. The included aged 18 or older HNCs undergoing therapy, without concurrent chemotherapy. Patients caused by conditions other than were excluded. randomly assigned intervention control groups. group received routine radiotherapy care during 3 months post‐treatment, while additional training. standard treatment post‐treatment. In addition, was instructed undergo preventive start treatment, measures (adjusting food texture, bite size, eating speed, posture utensils) implemented once discomfort occurred. Swallowing function assessed using Eating Assessment Tool‐10 (EAT‐10). Swallowing‐related measured M.D. Anderson Dysphagia Inventory (MDADI), which covers emotional, functional, physical global dimensions. Nutritional evaluated based Body Mass Index (BMI) Nutrition Risk Screening 2002 (NRS2002). Assessments performed baseline, immediately post‐treatment (within days after completion treatment) Results Ninety‐six enrolled this study, 48 group. Group effect analysis revealed that outperformed ( p = 0.002) overall 0.001). Time effects also indicated improvements compared baseline < 0.001), no interaction > 0.05). Specifically, observed functional dimension 0.001) MDADI total scores showed clinically difference (> 10 points) between However, between‐group differences found BMI values 0.474) NRS2002 0.957). Conclusion Our indicates combining effectively enhances HNC receiving therapy. insufficient evidence support its impact malnutrition risk. Trial Registration ClinicalTrials.gov identifier: ChiCTR2300067550
Язык: Английский
Процитировано
0International Journal of Particle Therapy, Год журнала: 2025, Номер 16, С. 100745 - 100745
Опубликована: Март 20, 2025
Язык: Английский
Процитировано
0Cancers, Год журнала: 2025, Номер 17(7), С. 1128 - 1128
Опубликована: Март 27, 2025
Background/Objectives: Malnutrition is a key determinant of quality life (QoL) in patients with head and neck cancers (HNCs), influencing treatment outcomes the occurrence adverse events (AEs). Despite there being numerous studies on nutritional status QoL, no standardized risk or prognostic model integrating clinical demographic factors. Methods: A literature search was conducted September 2024 Scopus, PubMed, Web Science, covering published between 2013 2024. Articles were selected based their relevance to AEs, interventions, QoL assessments HNC patients. Results: The factors include age, sex, weight, BMI, educational level, tumor features. Mucositis identified as most significant food intake-impairing AE, contributing malnutrition reduced QoL. Current rely descriptive questionnaires, which lack personalization predictive capabilities. Digital tools, including machine learning models digital twins, offer potential solutions for prediction personalized interventions. Conclusions: research efforts, assessment remains non-uniform, are lacking. comprehensive, approach needed, leveraging tools improve intervention strategies.
Язык: Английский
Процитировано
0Current Oncology, Год журнала: 2025, Номер 32(4), С. 220 - 220
Опубликована: Апрель 10, 2025
Many patients with head-and-neck cancer (HNC) suffer from speech or swallowing disorders. We investigated the impact of dysphagia on health-related quality life (HRQOL), functioning, and distress in HNC survivors, whether rehabilitation can alleviate these conditions. Before admission (T0) at discharge (T1) three-week inpatient rehabilitation, patient-reported outcomes were collected. HRQOL, symptoms, psychological assessed EORTC QLQ-C30 Hospital Anxiety Depression Scale (HADS) questionnaires. Of 63 patients, 22 had dysphagia, 23 needed no therapy (Control-1), 18 therapy, but showed symptoms (Control-2). physical, social, emotional functioning significantly lower than controls. Dysphagia reported more severe general including fatigue, pain, sleep disturbances, nausea/vomiting, diarrhea, financial worries. Furthermore, social Control-2 was worse Control-1. For all emotional, role insomnia, appetite loss improved T1. Improvements HRQOL most noticeable patients. Psychooncological counseling reduced depression to levels seen population. In conclusion, severely impaired systemic benefit substantially rehabilitation.
Язык: Английский
Процитировано
0Clinical Otolaryngology, Год журнала: 2025, Номер unknown
Опубликована: Апрель 14, 2025
ABSTRACT Objective To investigate the outcomes of iatrogenic oropharyngeal dysphagia and compare them with from different types aetiologies. Study Design Retrospective analysis. Setting This study was conducted on patients evaluated at a tertiary hospital's Swallowing Disorder Center using physical examination fibreoptic endoscopic evaluation swallowing (FEES) between January 2015 October 2021. Methods Patients were divided into six groups according to potential cause dysphagia: (1) Post head neck cancers (HNCs) treatment; (2) Post‐surgery for non‐cancerous aetiology; (3) Neurological; (4) Intracranial; (5) Head pathology; (6) Others. Of these, first second comprise caused by treatment (iatrogenic dysphagia). FEES results analysed Performance Status Scale (SPSS) Penetration Aspiration (PAS). Results 507 included, 146 (28.8%) had dysphagia, 361 (71.2%) non‐iatrogenic dysphagia. After therapy, 138 underwent follow‐up (47 91 intervention (compensatory technique food consistency changes), revealed significant improvement in group ( p < 0.001), while showed no after intervention. PAS SPSS scores also demonstrated greater group. Conclusions emphasises that is common entity disorders outpatient ENT clinic. It more likely persist resist conventional leading worse compared
Язык: Английский
Процитировано
0Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Апрель 16, 2025
Abstract The aim of this study was to validate the Swedish version Eating Assessment Tool (S-EAT-10) for head and neck cancer patients. participants (n = 60) had persistent swallowing difficulties 6–36 months after completion curative radiotherapy. videofluoroscopic assessed using Penetration Aspiration Scale Yale Pharyngeal Residue Severity Rating modified videofluoroscopy. Participants completed questionnaires S-EAT-10, M.D. Anderson Dysphagia Inventory (MDADI) study-specific questions. Internal consistency excellent test–retest reliability good. Regarding convergent validity, S-EAT-10 showed moderate strong correlation with MDADI no weak questions regarding meal duration weight change. criterion there a between instrumental measures. 85% sensitivity in identifying patients dysphagia. could not discriminate different degrees Thus, sufficient psychometric properties
Язык: Английский
Процитировано
0Current Oncology, Год журнала: 2025, Номер 32(4), С. 233 - 233
Опубликована: Апрель 16, 2025
Late radiation-associated dysphagia (late-RAD) remains a challenge in head and neck cancer (HNC) survivorship, despite advancements treatment methods. Although Fiberoptic Endoscopic Evaluation of Swallowing (FEES) stands as the preferred diagnostic approach for oropharyngeal assessment HNC population, current studies lack FEES-derived swallowing parameter characterization phenotypic classification within this specific cohort. This study sought to employ FEES-based characterize safety efficacy profiles, identify distinct phenotypes patients suffering from late-RAD, examine potential correlations between parameters. A retrospective analysis included twenty-four post-radiotherapy evaluated using standardized FEES protocols across three bolus consistencies (liquid, semisolid, solid). was quantified Penetration–Aspiration Scale (PAS), while measured via Yale Pharyngeal Residue Severity Rating (YPRSRS). Additionally, six were characterized Propulsion deficit predominant phenotype (92%), followed by delayed pharyngeal phase (37.5%) protective (25%), with 46% exhibiting multiple phenotypes. Unsafe occurred most frequently liquid consistency (62.5%), residue prevalent semisolid (82.6% valleculae, 52.2% pyriform sinuses) solid (92.3% 53.8% sinuses). Significant found penetration–aspiration scores (p < 0.05). examination revealed late dysphagia, predominance propulsion significant interdependence
Язык: Английский
Процитировано
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