Journal of Medical Internet Research,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 24, 2024
Chronic
diseases
are
a
major
global
health
burden,
accounting
for
nearly
three-quarters
of
the
deaths
worldwide.
Large
language
models
(LLMs)
advanced
artificial
intelligence
systems
with
transformative
potential
to
optimize
chronic
disease
management;
however,
robust
evidence
is
lacking.
This
review
aims
synthesize
on
feasibility,
opportunities,
and
challenges
LLMs
across
management
spectrum,
from
prevention
screening,
diagnosis,
treatment,
long-term
care.
Following
PRISMA
(Preferred
Reporting
Items
Systematic
Reviews
Meta-Analysis)
guidelines,
11
databases
(Cochrane
Central
Register
Controlled
Trials,
CINAHL,
Embase,
IEEE
Xplore,
MEDLINE
via
Ovid,
ProQuest
Health
&
Medicine
Collection,
ScienceDirect,
Scopus,
Web
Science
Core
China
National
Knowledge
Internet,
SinoMed)
were
searched
April
17,
2024.
Intervention
simulation
studies
that
examined
in
included.
The
methodological
quality
included
was
evaluated
using
rating
rubric
designed
simulation-based
research
risk
bias
nonrandomized
interventions
tool
quasi-experimental
studies.
Narrative
analysis
descriptive
figures
used
study
findings.
Random-effects
meta-analyses
conducted
assess
pooled
effect
estimates
feasibility
management.
A
total
20
general-purpose
(n=17)
retrieval-augmented
generation-enhanced
(n=3)
diseases,
including
cancer,
cardiovascular
metabolic
disorders.
demonstrated
spectrum
by
generating
relevant,
comprehensible,
accurate
recommendations
(pooled
rate
71%,
95%
CI
0.59-0.83;
I2=88.32%)
having
higher
accuracy
rates
compared
(odds
ratio
2.89,
1.83-4.58;
I2=54.45%).
facilitated
equitable
information
access;
increased
patient
awareness
regarding
ailments,
preventive
measures,
treatment
options;
promoted
self-management
behaviors
lifestyle
modification
symptom
coping.
Additionally,
facilitate
compassionate
emotional
support,
social
connections,
care
resources
improve
outcomes
diseases.
However,
face
addressing
privacy,
language,
cultural
issues;
undertaking
tasks,
medication,
comorbidity
personalized
regimens
real-time
adjustments
multiple
modalities.
have
transform
at
individual,
social,
levels;
their
direct
application
clinical
settings
still
its
infancy.
multifaceted
approach
incorporates
data
security,
domain-specific
model
fine-tuning,
multimodal
integration,
wearables
crucial
evolution
into
invaluable
adjuncts
professionals
PROSPERO
CRD42024545412;
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024545412.
Otolaryngology,
Год журнала:
2024,
Номер
171(3), С. 667 - 677
Опубликована: Май 8, 2024
To
review
the
current
literature
on
application,
accuracy,
and
performance
of
Chatbot
Generative
Pre-Trained
Transformer
(ChatGPT)
in
Otolaryngology-Head
Neck
Surgery.
PubMED,
Cochrane
Library,
Scopus.
A
comprehensive
applications
ChatGPT
otolaryngology
was
conducted
according
to
Preferred
Reporting
Items
for
Systematic
Reviews
Meta-analyses
statement.
provides
imperfect
patient
information
or
general
knowledge
related
diseases
found
In
clinical
practice,
despite
suboptimal
performance,
studies
reported
that
model
is
more
accurate
providing
diagnoses,
than
suggesting
most
adequate
additional
examinations
treatments
vignettes
real
cases.
has
been
used
as
an
adjunct
tool
improve
scientific
reports
(referencing,
spelling
correction),
elaborate
study
protocols,
take
student
resident
exams
reporting
several
levels
accuracy.
The
stability
responses
throughout
repeated
questions
appeared
high
but
many
some
hallucination
events,
particularly
references.
date,
are
limited
generating
disease
treatment
information,
improvement
management
lack
comparison
with
other
large
language
models
main
limitation
research.
Its
ability
analyze
images
not
yet
investigated
although
upper
airway
tract
ear
important
step
diagnosis
common
ear,
nose,
throat
conditions.
This
may
help
otolaryngologists
conceive
new
further
Bioengineering,
Год журнала:
2024,
Номер
11(4), С. 342 - 342
Опубликована: Март 31, 2024
Large
language
models
(LLMs)
are
transformer-based
neural
networks
that
can
provide
human-like
responses
to
questions
and
instructions.
LLMs
generate
educational
material,
summarize
text,
extract
structured
data
from
free
create
reports,
write
programs,
potentially
assist
in
case
sign-out.
combined
with
vision
interpreting
histopathology
images.
have
immense
potential
transforming
pathology
practice
education,
but
these
not
infallible,
so
any
artificial
intelligence
generated
content
must
be
verified
reputable
sources.
Caution
exercised
on
how
integrated
into
clinical
practice,
as
produce
hallucinations
incorrect
results,
an
over-reliance
may
lead
de-skilling
automation
bias.
This
review
paper
provides
a
brief
history
of
highlights
several
use
cases
for
the
field
pathology.
Diagnostics,
Год журнала:
2024,
Номер
14(17), С. 1879 - 1879
Опубликована: Авг. 27, 2024
Artificial
intelligence
(AI)
is
making
notable
advancements
in
the
medical
field,
particularly
bone
fracture
detection.
This
systematic
review
compiles
and
assesses
existing
research
on
AI
applications
aimed
at
identifying
fractures
through
imaging,
encompassing
studies
from
2010
to
2023.
It
evaluates
performance
of
various
models,
such
as
convolutional
neural
networks
(CNNs),
diagnosing
fractures,
highlighting
their
superior
accuracy,
sensitivity,
specificity
compared
traditional
diagnostic
methods.
Furthermore,
explores
integration
advanced
imaging
techniques
like
3D
CT
MRI
with
algorithms,
which
has
led
enhanced
accuracy
improved
patient
outcomes.
The
potential
Generative
Large
Language
Models
(LLMs),
OpenAI’s
GPT,
enhance
processes
synthetic
data
generation,
comprehensive
report
creation,
clinical
scenario
simulation
also
discussed.
underscores
transformative
impact
workflows
care,
while
gaps
suggesting
future
directions
quality,
model
robustness,
ethical
considerations.
Confocal
laser
endomicroscopy
(CLE)
enables
real-time
diagnosis
of
oral
cancer
and
potentially
malignant
disorders
by
in
vivo
microscopic
tissue
examination.
One
impediment
to
the
widespread
clinical
adoption
this
technology
is
need
for
operator
expertise
image
interpretation.
Here
we
review
application
AI
automatic
classification
CLE
images
discuss
opportunities
integrating
advance
digital
pathology
thus
improving
speed,
precision
reproducibility.
Australasian Journal of Dermatology,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 6, 2025
ABSTRACT
In
computational
linguistics,
large
language
models
have
reached
a
significant
turning
point.
They
quickly
spread
throughout
several
sectors,
including
the
medical
field.
By
integrating
demographics,
clinical
photos,
interviews,
or
genetic
data
where
appropriate,
these
technologies
may
offer
deeper
insights
into
patient
in
dermatology.
also
recommendations
for
suitable
diagnosis
and
treatment.
Their
work
dermatology
influence
education
interactions
with
doctors
by
addressing
patients'
questions
developing
materials,
addition
to
enhancing
diagnostic
procedures
treatment
schedule
planning.
Through
thorough
systematic
evaluation
of
publicly
accessible
big
model
applications
dermatology,
paper
seeks
close
current
gap
highlighting
previously
published
research,
identifying
important
obstacles,
investigating
potential
future
directions.
arXiv (Cornell University),
Год журнала:
2024,
Номер
11, С. 1395934 - 1395934
Опубликована: Янв. 1, 2024
ChatGPT,
the
most
accessible
generative
artificial
intelligence
(AI)
tool,
offers
considerable
potential
for
veterinary
medicine,
yet
a
dedicated
review
of
its
specific
applications
is
lacking.
This
concisely
synthesizes
latest
research
and
practical
ChatGPT
within
clinical,
educational,
domains
medicine.
It
intends
to
provide
guidance
actionable
examples
how
AI
can
be
directly
utilized
by
professionals
without
programming
background.
For
practitioners,
extract
patient
data,
generate
progress
notes,
potentially
assist
in
diagnosing
complex
cases.
Veterinary
educators
create
custom
GPTs
student
support,
while
students
utilize
exam
preparation.
aid
academic
writing
tasks
research,
but
publishers
have
set
requirements
authors
follow.
Despite
transformative
potential,
careful
use
essential
avoid
pitfalls
like
hallucination.
addresses
ethical
considerations,
provides
learning
resources,
tangible
guide
responsible
implementation.
A
table
key
takeaways
was
provided
summarize
this
review.
By
highlighting
benefits
limitations,
equips
veterinarians,
educators,
researchers
harness
power
effectively.
Abstract
Purpose
Large
language
models
(LLMs)
are
pivotal
in
artificial
intelligence,
demonstrating
advanced
capabilities
natural
understanding
and
multimodal
interactions,
with
significant
potential
medical
applications.
This
study
explores
the
feasibility
efficacy
of
LLMs,
specifically
ChatGPT-4o
Claude
3-Opus,
classifying
thyroid
nodules
using
ultrasound
images.
Methods
included
112
patients
a
total
116
nodules,
comprising
75
benign
41
malignant
cases.
Ultrasound
images
these
were
analyzed
3-Opus
to
diagnose
or
nature
nodules.
An
independent
evaluation
by
junior
radiologist
was
also
conducted.
Diagnostic
performance
assessed
Cohen’s
Kappa
receiver
operating
characteristic
(ROC)
curve
analysis,
referencing
pathological
diagnoses.
Results
demonstrated
poor
agreement
results
(
=
0.116),
while
showed
even
lower
0.034).
The
exhibited
moderate
0.450).
achieved
an
area
under
ROC
(AUC)
57.0%
(95%
CI:
48.6–65.5%),
slightly
outperforming
(AUC
52.0%,
95%
43.2–60.9%).
In
contrast,
significantly
higher
AUC
72.4%
63.7–81.1%).
unnecessary
biopsy
rates
41.4%
for
ChatGPT-4o,
43.1%
12.1%
radiologist.
Conclusion
While
LLMs
such
as
show
promise
future
applications
imaging,
their
current
use
clinical
diagnostics
should
be
approached
cautiously
due
limited
accuracy.