From brain fog to COVID toe: A head-to-toe review of long COVID DOI
Jamie K. Stone, Sarah Berman,

Wendy Zheng

и другие.

American Journal of Pharmacotherapy and Pharmaceutical Sciences, Год журнала: 2023, Номер 2, С. 12 - 12

Опубликована: Сен. 16, 2023

With the World Health Organization’s announcement of end coronavirus disease 2019 (COVID-19) public health emergency, both clinicians and patients may think that COVID-19 era is over. While pandemic have ended, acute infections continue to occur as severe respiratory syndrome 2 (SARS-CoV-2) virus transitions endemic phase. After initial infection, approximately 20% experience persistent symptoms for more than 4 weeks. This clinical phenomenon often termed “long COVID” but many other terms exist in literature including “Post-COVID-19 syndrome,” “Chronic COVID-19,” haul COVID,” “post-acute “long-term sequelae,” sequelae SARS-CoV-2 infection,” among others. For purposes this review, we define long COVID occurring weeks after infection. Long manifests a wide variety symptoms, cough, fatigue, muscle weakness, cognitive impairment, shortness breath, chest pain. In fact, current indicates has effects throughout every major organ system. Within compile summarize available data regarding using head-to-toe approach. review meant be comprehensive covering following systems: neurologic, cardiac, pulmonary, gastrointestinal, hepatic, renal, genitourinary, hematologic, musculoskeletal, integumentary. The purpose narrative provide broad inclusive resource on symptomatology, pathophysiology, potential treatments.

Язык: Английский

Experiences of physiotherapists working with adults living with Long COVID in Canada: a qualitative study DOI Creative Commons

Caleb Kim,

Chantal Lin,

Michelle S. Wong

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Март 12, 2024

ABSTRACT Objectives To explore experiences of physiotherapists working with adults living Long COVID in Canada. Design Cross-sectional descriptive qualitative study involving online semi-structured interviews. Participants We recruited Canada who self-identified as having clinically treated one or more the past year. Data collection Using an interview guide, we inquired about physiotherapists’ knowledge COVID, assessment and treatment experiences, perspectives on roles, contextual implementation factors influencing rehabilitative outcomes, their recommendations for rehabilitation. Interviews were audio-recorded, transcribed verbatim, analyzed using a group-based thematic analytical approach. administered demographic questionnaire to describe sample characteristics. Results Thirteen from five provinces participated; most women (n=8;62%) practised urban settings (n=11;85%). reported variable amounts existing guidelines Physiotherapists characterized dynamic process involving: 1) disruption profession (encountering new patient population pivoting models care delivery), followed by 2) cyclical learning curves evolving roles persons (navigating uncertainty, keeping up rapidly-emerging evidence, trial error, adapting mindset approaches, growing prominence advocate collaborator). recommended need education training, active open-minded listening patients, interdisciplinary care, organizational- system-level improvements foster access care. Conclusions Physiotherapists’ involved Not all participants demonstrated in-depth understanding rehabilitation guidelines. may help inform physiotherapy STRENGTHS AND LIMITATIONS OF THIS STUDY our knowledge, this is first studies patients Our approach, interviews, enabled exploration into Canadian perceived treatment, acquisition, facilitators barriers delivery services. team-based approach partnership part provided valuable collaboration, guidance, advice refining guide fostering student researcher skills increase quality study. The diversity participants’ characteristics different practice across variability number individuals strengths However, Canada, transferability other geographical contexts including rural countries be limited, especially those larger differences healthcare systems.

Язык: Английский

Процитировано

0
Post-COVID syndrome - novel clinical findings DOI
Kristina Adorjan, Daniel Martins‐de‐Souza, Martin Walter

и другие.

European Archives of Psychiatry and Clinical Neuroscience, Год журнала: 2024, Номер unknown

Опубликована: Сен. 12, 2024

Язык: Английский

Процитировано

0
Spinal Neuromodulation for Respiratory Rehabilitation in Patients with Post-Acute COVID-19 Syndrome DOI Creative Commons
Alexander V. Ovechkin, Т. Р. Мошонкина, Natalia Shandybina

и другие.

Life, Год журнала: 2024, Номер 14(11), С. 1518 - 1518

Опубликована: Ноя. 20, 2024

(1) Background: Neurological deficits associated with coronavirus disease (COVID-19) exacerbate respiratory dysfunction, necessitating rehabilitation strategies that address both. Previous studies have demonstrated spinal cord transcutaneous stimulation (scTS) can facilitate the excitation of neural networks in patients post-COVID-19 syndrome. This study evaluates efficacy combining scTS training (RT) to improve function individuals pulmonary deficits; (2) Methods: In this before-after, case-controlled clinical trial, five post-acute COVID-19 participated two interventional programs: 10 daily sessions (RT), followed by combined RT (scTS + RT). Forced vital capacity (FVC), peak inspiratory flow (PIF), expiratory (PEF), time-to-peak (tPIF), and (tPEF) were assessed at baseline after each program; (3) Results: Compared alone, intervention resulted an average effect size was twice as large, significant increases FVC PEF, a decrease tPEF; (4) Conclusions: The scTS-induced activation neuronal networks, when training, offers promising therapeutic approach for treating persistent

Язык: Английский

Процитировано

0
Long-Term Pulmonary Sequelae and Immunological Markers in Patients Recovering from Severe and Critical COVID-19 Pneumonia: A Comprehensive Follow-Up Study DOI Creative Commons

Edita Strumilienė,

Jurgita Urbonienė,

Laimutė Jurgauskienė

и другие.

Medicina, Год журнала: 2024, Номер 60(12), С. 1954 - 1954

Опубликована: Ноя. 27, 2024

Background and Objectives: Severe critical COVID-19 pneumonia can lead to long-term complications, especially affecting pulmonary function immune health. However, the extent progression of these complications over time are not well understood. This study aimed assess lung function, radiological changes, some parameters in survivors severe up 12 months after hospital discharge. Materials Methods: prospective observational cohort followed 85 adult patients who were hospitalized with or at a tertiary care Vilnius, Lithuania, for post-discharge. Pulmonary tests (PFTs), including forced vital capacity (FVC), expiratory volume 1 s (FEV1), diffusion carbon monoxide (DLCO), conducted 3, 6, months. High-resolution chest computed tomography (CT) scans assessed residual inflammatory profibrotic/fibrotic abnormalities. Lymphocyte subpopulations evaluated via flow cytometry during follow-up visits monitor status. Results: The median age was 59 years (IQR: 51–64). Fifty-three (62.4%) had disease. improved significantly time, increases FVC, FEV1, VC, TLC, DLCO. Residual (RV) did change suggesting that aspects such as air trapping, remained stable may require attention care. percentage restrictive spirometry patterns decreased from 24.71% 3 14.8% (p < 0.05). changes on CT present 77.63% 6 months, decreasing 69.62% 0.001). Profibrotic prevalent, 82.89% 73.08% counts declined (2077 cells/µL vs. 1845 cells/µL, p = 0.034), notable reductions CD3+ 0.040), CD8+ 0.007), activated CD3HLA-DR+ cells found higher CD4+ T cell associated worse particularly reduced total (TLC), while levels linked outcomes, increased (FVC) (VC). Multivariable regression analyses revealed CD4+/CD28+/CD192+ worsening CD8+/CD28+/CD192+ better indicating dysregulation plays role respiratory recovery. Conclusions: Survivors continue experience significant impairments system Regular monitoring is essential guiding personalized post-COVID-19 improving outcomes. Further research needed explore mechanisms behind develop targeted interventions long COVID-19.

Язык: Английский

Процитировано

0
From brain fog to COVID toe: A head-to-toe review of long COVID DOI
Jamie K. Stone, Sarah Berman,

Wendy Zheng

и другие.

American Journal of Pharmacotherapy and Pharmaceutical Sciences, Год журнала: 2023, Номер 2, С. 12 - 12

Опубликована: Сен. 16, 2023

With the World Health Organization’s announcement of end coronavirus disease 2019 (COVID-19) public health emergency, both clinicians and patients may think that COVID-19 era is over. While pandemic have ended, acute infections continue to occur as severe respiratory syndrome 2 (SARS-CoV-2) virus transitions endemic phase. After initial infection, approximately 20% experience persistent symptoms for more than 4 weeks. This clinical phenomenon often termed “long COVID” but many other terms exist in literature including “Post-COVID-19 syndrome,” “Chronic COVID-19,” haul COVID,” “post-acute “long-term sequelae,” sequelae SARS-CoV-2 infection,” among others. For purposes this review, we define long COVID occurring weeks after infection. Long manifests a wide variety symptoms, cough, fatigue, muscle weakness, cognitive impairment, shortness breath, chest pain. In fact, current indicates has effects throughout every major organ system. Within compile summarize available data regarding using head-to-toe approach. review meant be comprehensive covering following systems: neurologic, cardiac, pulmonary, gastrointestinal, hepatic, renal, genitourinary, hematologic, musculoskeletal, integumentary. The purpose narrative provide broad inclusive resource on symptomatology, pathophysiology, potential treatments.

Язык: Английский

Процитировано

0