Journal of Clinical Medicine,
Год журнала:
2023,
Номер
12(9), С. 3222 - 3222
Опубликована: Апрель 30, 2023
Rehabilitation
via
virtual
reality
(VR)
training
tools
allows
repetitive,
intensive,
and
task-specific
practice
in
a
controlled
safe
environment.
Our
goal
was
to
develop
validate
novel
immersive
VR
system
based
on
the
of
real-life
activities
kitchen
environment
people
with
multiple
sclerosis
(pwMS)
upper-limb
dysfunction.
The
application
includes
several
tasks,
i.e.,
tidying
up
kitchen,
preparing
hamburger
soup
meal,
dish
washing.
Following
development
phase,
tested
for
an
8-week
intervention
period
small
sample
pwMS
suffering
from
Suitability
Evaluation
Questionnaire
systems
served
as
primary
outcome.
scores
enjoyment,
sense
comfort
system,
feelings
success
control,
realism,
easy-to-understand
instructions,
assists
rehabilitation
therapy,
were
between
4.0
4.6,
indicating
high
satisfaction.
eye
discomfort,
dizziness,
nausea,
disorientation
during
2.8
1.3,
low-to-moderate
interference
system.
is
feasible
paves
way
future
RCTs
examine
benefits
compared
standard
care,
thus
improving
functionality
upper
limbs
pwMS.
Neural Regeneration Research,
Год журнала:
2023,
Номер
19(8), С. 1768 - 1771
Опубликована: Ноя. 8, 2023
In
multiple
sclerosis,
only
immunomodulatory
and
immunosuppressive
drugs
are
recognized
as
disease-modifying
therapies.
However,
in
recent
years,
several
data
from
pre-clinical
clinical
studies
suggested
a
possible
role
of
physical
exercise
therapy
sclerosis.
Current
evidence
is
sparse
often
conflicting,
the
mechanisms
underlying
neuroprotective
antinflammatory
sclerosis
have
not
been
fully
elucidated.
Data,
mainly
derived
studies,
suggest
that
could
enhance
long-term
potentiation
thus
neuroplasticity,
reduce
neuroinflammation
synaptopathy,
dampen
astrogliosis
microgliosis.
humans,
most
trials
focused
on
direct
MRI
outcomes,
investigating
synaptic,
neuroinflammatory,
pathological
changes
straightforward
compared
to
animal
models.
The
present
review
analyzed
current
limitations
research
concerning
potential
effects
models
human
studies.
