Enhancing the Efficacy of Active Pharmaceutical Ingredients in Medicinal Plants through Nanoformulations: A Promising Field
Nanomaterials,
Год журнала:
2024,
Номер
14(19), С. 1598 - 1598
Опубликована: Окт. 3, 2024
This
article
explores
the
emerging
field
of
nanomedicine
as
a
drug
delivery
system,
aimed
at
enhancing
therapeutic
efficacy
active
pharmaceutical
ingredients
in
medicinal
plants.
The
traditional
methods
applying
plants
present
several
limitations,
such
low
bioavailability,
poor
solubility,
challenges
accurately
controlling
dosage,
and
inadequate
targeting.
Nanoformulations
represent
an
innovative
approach
preparation
that
employs
nanotechnology
to
produce
nanoscale
particles
or
carriers,
which
are
designed
overcome
these
limitations.
offer
distinct
advantages,
significantly
solubility
bioavailability
drugs,
particularly
for
poorly
soluble
components
These
formulations
effectively
enhance
thereby
facilitating
better
absorption
utilization
by
human
body,
turn
improves
efficacy.
Furthermore,
enables
targeted
delivery,
ensuring
precise
administration
lesion
site
minimizing
side
effects
on
healthy
tissues.
Additionally,
nanoformulations
can
regulate
release
rates,
extend
duration
action,
stability
treatment
effects.
However,
certain
limitations
potential
risks;
their
safety
require
further
investigation,
regarding
toxicity
with
long-term
use.
Nevertheless,
nanomaterials
demonstrate
substantial
augmenting
plants,
offering
novel
approaches
methodologies
development
application.
Язык: Английский
Pharmacological and Therapeutic Biofunction of Dendrobium nobile: A Critical Review
Natural Product Communications,
Год журнала:
2024,
Номер
19(11)
Опубликована: Ноя. 1, 2024
Dendrobium
nobile
(
D.
nobile),
an
orchid
species
deeply
rooted
in
traditional
medicine,
has
garnered
considerable
attention
for
its
potential
pharmacological
and
therapeutic
properties.
This
critical
review
provides
a
comprehensive
analysis
of
the
bioactive
compounds
present
explores
their
diverse
effects.
The
phytochemistry
been
discussed,
highlighting
major
constituents
with
specific
profile
investigated
various
domains.
Notably,
strong
antioxidant
activity
ability
to
scavenge
free
radicals
have
shown
support
immune-modulating,
anti-inflammatory,
neuroprotective
Intriguingly,
these
orchids
display
promising
anticancer,
antidiabetic,
cardiovascular,
renoprotective,
hepatoprotective,
wound-healing
mechanisms
underlying
effects
were
explored,
including
molecular
pathways
signalling
cascades.
However,
factors
influencing
chemical
composition,
such
as
environmental
conditions,
cultivation
techniques,
postharvest
processing,
must
be
considered
consistent
outcomes.
safety
toxicity
profiles
derived
from
acute
chronic
studies
examined.
In
future
studies,
exploring
untapped
elucidating
intricate
action
are
promising.
underscores
richness
nobile,
revealing
contribute
modern
medicine
while
emphasising
need
further
investigation
harness
full
benefits.
Язык: Английский
Comprehensive analysis of Perilla frutescens (L.) Britt. along the value chain in northeast Inner Mongolia
Science of Traditional Chinese Medicine,
Год журнала:
2024,
Номер
2(2), С. 158 - 168
Опубликована: Июнь 1, 2024
Abstract
Objective
To
ensure
the
quality
of
Perilla
frutescens
(L.)
Britt.
and
improve
associated
benefits
for
stakeholders,
this
study
analyzed
influences
different
circulation
channels
stakeholders
on
quality,
price,
other
factors
P.
with
consideration
to
distribution.
Method
We
interviewed
local
e-commerce
platforms
in
Oroqen
Autonomous
Banner
Morin
Dawa
Daur
regarding
origin,
circulation,
distribution,
prices
medicinal
parts
.
In
addition,
maximum
entropy
model
was
used
predict
potential
distribution
area.
According
Chinese
Pharmacopeia
(2020
edition),
we
measured
content
index
components
collected
Perillae
Folium,
Caulis,
Fructus
samples
evaluated
by
quantitative
cluster
analyses.
Remote
sensing
employed
distinguish
calculate
area
highly
suitable
regions.
The
autoregressive
integrated
moving
average
adopted
analyze
price
Result
results
showed
8
value
chains
cooperation
chain
between
farmers
enterprises
could
maximize
all
guarantee
materials.
regionalization
analysis
that
most
planting
junction
Banner.
Chemical
Caulis
were
unqualified
mostly
purchased
from
platforms.
identified
5
land
types,
among
which
cultivated
3247.7501
km
2
a
rising
trend,
although
trend
slowed
down.
Conclusion
This
involved
various
links
production
materials
consumption
consumers,
can
help
facilitate
future
research
any
link.
findings
promote
development
industry
Язык: Английский
Correlation analysis between Radix Pseudostelariae quality and rhizosphere soil factors of Pseudostellaria heterophylla in a cultivation region, China
Journal of the Science of Food and Agriculture,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 13, 2024
Abstract
BACKGROUND
Pseudostellaria
heterophylla
,
known
for
its
significant
bioactive
ingredients,
offers
potential
health
benefits.
Amounts
of
compounds
the
tuberous
root
cultivated
are
sensitive
to
environmental
conditions.
We
selected
22
sampling
sites
in
Guizhou
Province,
China,
a
primary
planting
area.
analyzed
polysaccharides,
water‐soluble
extractives,
total
ash
and
inorganic
elements
(Fe,
Mn,
Zn,
Mg
Ca)
Radix
Pseudostellariae,
pH,
organic
carbon
(OC),
available
nitrogen
(AN),
phosphorus
(AP),
potassium
(AK)
soil.
RESULTS
Our
study
revealed
substantial
presence
polysaccharides
(85.00–181.00
mg
g
−1
),
extractives
(47.52–57.63%)
(1.87–3.39%)
Pseudostellariae.
Polysaccharides
showed
no
sensitivity
soil
pH.
Pseudostellariae
collected
from
with
pH
>
7
exhibited
slightly
higher
levels
Ca
than
that
<
5.
Conversely,
less
5
had
OC,
AN,
AP
AK
contents.
Water‐soluble
were
negatively
correlated
but
positively
OC
AN.
CONCLUSION
The
results
imply
sequestration
nutrients
over
long‐term
cultivation
could
impact
accumulation
some
ingredients
This
has
profound
implication
enhancing
quality
artificially
.
©
2024
Society
Chemical
Industry.
Язык: Английский
Multi-Indicator Comprehensive Quality Evaluation of Turpinia arguta (Lindl.) Seem Herbs at Different Harvesting Periods
Agronomy,
Год журнала:
2024,
Номер
14(11), С. 2658 - 2658
Опубликована: Ноя. 12, 2024
This
study
aimed
to
investigate
differences
in
the
leaf
biomasses,
chemical
compositions,
and
pharmacological
activities
of
Turpinia
arguta
histocultured
seedlings
live
at
different
harvesting
periods
(S1,
S2,
S3,
S4)
order
determine
optimal
period.
Eleven
indexes,
including
biomass,
key
active
components,
secondary
metabolites,
nutrient
content,
antioxidant
activity,
were
evaluated
by
high-performance
liquid
chromatography
colorimetric
methods
during
periods.
The
weights
11
indexes
calculated
principal
component
analysis,
then
a
comprehensive
quality
evaluation
was
performed.
results
showed
significant
contents,
between
highest
score
obtained
for
S4
period,
indicating
that
T.
best
this
time
period
most
suitable
At
(S4),
medicinal
higher
than
those
seedlings,
importance
tissue
culture
technology
enhancing
arguta.
provides
more
novel
abundant
information
reference
determining
appropriate
arguta,
with
aim
providing
newer
scientific
guidance
management
herbs.
Язык: Английский