Adolescents with Persistent Symptoms Following Acute SARS-CoV-2 Infection (Long-COVID): Symptom Profile, Clustering and Follow-Up Symptom Evaluation DOI Creative Commons
Marco Floridia, Danilo Buonsenso,

Laura Macculi

и другие.

Children, Год журнала: 2024, Номер 12(1), С. 28 - 28

Опубликована: Дек. 27, 2024

Background: Few studies have evaluated long-COVID in adolescents. Methods: Cohort study. Demographics, clinical data, and the presence of 30 symptoms were collected with a modified WHO form. Mean values compared by Student’s t test proportions chi-square or Fisher test, trends over time analysed using for trend. Potential risk factors independently associated persisting multivariable logistic regression model. Clustering cases was two-step automatic clustering. Results: A total 97 adolescents aged 12–17 (54.6% females, 45.4% males) evaluated. After mean interval 96 days (SD 52) from acute infection, number (2.8 overall) higher pre-Omicron (3.2 vs. 2.5 Omicron, p = 0.046) moderate/severe infections (4.2 2.7 mild, 0.023). Fatigue (62.9%) dyspnea (43.3%) most common symptoms, followed headache (28.9%), thoracic pain (22.7%), diarrhea (20.6%), palpitations/tachycardia (17.5%), articular (15.5%), difficult concentration (14.4%), muscle (12.4%), taste reduction (8.2%), smell fever (6.2%), skin disorders (5.2%). The symptom profile similar males females but showed significant differences that observed concurrently adults. 340 45.3% still presented persistence initial symptoms. Two clusters defined differed phase infection Conclusions: Long-COVID manifestations may differ those Polisymptomaticity predict long-term persistence.

Язык: Английский

Experiences of physiotherapists working with adults living with Long COVID in Canada: a qualitative study DOI Creative Commons

Caleb Kim,

Chantal Lin,

Michelle S. Wong

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Март 12, 2024

ABSTRACT Objectives To explore experiences of physiotherapists working with adults living Long COVID in Canada. Design Cross-sectional descriptive qualitative study involving online semi-structured interviews. Participants We recruited Canada who self-identified as having clinically treated one or more the past year. Data collection Using an interview guide, we inquired about physiotherapists’ knowledge COVID, assessment and treatment experiences, perspectives on roles, contextual implementation factors influencing rehabilitative outcomes, their recommendations for rehabilitation. Interviews were audio-recorded, transcribed verbatim, analyzed using a group-based thematic analytical approach. administered demographic questionnaire to describe sample characteristics. Results Thirteen from five provinces participated; most women (n=8;62%) practised urban settings (n=11;85%). reported variable amounts existing guidelines Physiotherapists characterized dynamic process involving: 1) disruption profession (encountering new patient population pivoting models care delivery), followed by 2) cyclical learning curves evolving roles persons (navigating uncertainty, keeping up rapidly-emerging evidence, trial error, adapting mindset approaches, growing prominence advocate collaborator). recommended need education training, active open-minded listening patients, interdisciplinary care, organizational- system-level improvements foster access care. Conclusions Physiotherapists’ involved Not all participants demonstrated in-depth understanding rehabilitation guidelines. may help inform physiotherapy STRENGTHS AND LIMITATIONS OF THIS STUDY our knowledge, this is first studies patients Our approach, interviews, enabled exploration into Canadian perceived treatment, acquisition, facilitators barriers delivery services. team-based approach partnership part provided valuable collaboration, guidance, advice refining guide fostering student researcher skills increase quality study. The diversity participants’ characteristics different practice across variability number individuals strengths However, Canada, transferability other geographical contexts including rural countries be limited, especially those larger differences healthcare systems.

Язык: Английский

Процитировано

0

The risks of autoimmune- and inflammatory post-acute COVID-19 conditions: a network cohort study in six European countries, the US, and Korea DOI Creative Commons
Theresa Burkard, Kim López‐Güell, Martí Català

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Май 15, 2024

ABSTRACT Objectives We aimed to assess the risk of autoimmune- and inflammatory post-acute COVID-19 conditions. Design Descriptive network cohort study. Setting Electronic health records from UK Dutch primary care, Norwegian linked registry, hospital specialist centres in Spain, France, Korea, healthcare claims Estonia US. Participants followed individuals between September 2020 latest available data day they fulfilled at least 365 days prior observation (general population), additionally 91 after a SARS-Cov-2 negative test (comparator) or record (exposed patients). Main outcome measures assessed postural orthostatic tachycardia syndrome (POTS) diagnoses/symptoms, myalgic encephalomyelitis / chronic fatigues (ME/CFS) multi-inflammatory (MIS), several autoimmune diseases. For contextualisation, we any diabetes mellitus (DM). Meta-analysed crude incidence rate ratios (IRR) outcomes versus testing yield absolute risks. Furthermore, rates (IR) general population describe total disease burden. Results included 34’549’575 whom 2’521’812 had COVID-19, 4’233’145 first test. After compared patients, observed IRRs 1.24 (1.23-1.25), 1.22 (1.21-1.23), 1.12 (1.04-1.21) for POTS symptoms, ME/CFS symptoms diagnoses, respectively. In contrast, diseases DM did not higher COVID-19. individual database populations, IRs diagnoses were 17-1’477/100’000 person-years (pys) 2-473/100’000 pys, MIS lowest with 0.4-16/100’000 those as benchmark 8-86/100’000 pys. largely depended on care setting. Conclusion our unmatched comparison, that, following yielded than testing. terms, have similar burden DM. WHAT IS ALREADY KNOWN ON THIS TOPIC Observational research suggested positive associations so called conditions, whose spectrum is yet be established Basic pathways that link such (POTS), (ME/CFS), multiple STUDY ADDS symptoms/diagnoses was testing, increased working age group children elderly Disease burdens among women men overall

Язык: Английский

Процитировано

0

Long-term gastrointestinal symptoms and sleep quality sequelae in adolescents after COVID-19: a retrospective study DOI Creative Commons

Wei-Lin Yang,

Qi Wang,

Ying Wang

и другие.

Frontiers in Public Health, Год журнала: 2024, Номер 12

Опубликована: Май 21, 2024

Objective To evaluate the long-term gastrointestinal (GI) symptoms and sleep quality sequelae in adolescents with COVID-19. Methods Between June July 2023, an online survey was done Xiaoshan District, Hangzhou City, Zhejiang Province, China, using GI Symptom Rating Scale (GSRS) Pittsburgh Sleep Quality Inventory (PSQI). Results COVID-19 patients increased by 11.86% compared to before infection, while decreased 10.9%. Over time, there a significant increase cumulative incidence rate of disorders ( p < 0.001). Follow-up positive within 6 months infection showed that began ease starting from first month after infection. Further analysis indicated linear relationship between severity (R > 0.5, Moreover, females, older age, higher education were identified as risk factors influencing effects Conclusion SARS-CoV-2 affects during both acute phase post-infection periods. these gradually alleviate. A correlation exists quality.

Язык: Английский

Процитировано

0

Exploring the prevalence and chest CT predictors of Long COVID in children: a comprehensive study from Shanghai and Linyi DOI Creative Commons
Yong Yin, Guijun Yang, Na Wang

и другие.

Frontiers in Pediatrics, Год журнала: 2024, Номер 12

Опубликована: Авг. 7, 2024

COVID-19 constitutes a pandemic of significant detriment to human health. This study aimed investigate the prevalence Long COVID following SARS-CoV-2 infection, analyze potential predictors chest CT for development in children.

Язык: Английский

Процитировано

0

Effect of water- and land-based exercise on lung function in children with post COVID-19 condition: secondary results from a randomized controlled trial DOI
Anna Ogonowska-Słodownik, Marta Kinga Łabęcka, Agnieszka Maciejewska

и другие.

Authorea (Authorea), Год журнала: 2024, Номер unknown

Опубликована: Авг. 25, 2024

Objectives: This study aimed to assess the effect of water- and land-based exercise on lung function in children with post COVID-19 condition. Methods: was a randomized controlled trial. Children condition aged 10-12 years were randomly assigned water-based (AQUA), (LAND), or control group no (CONTROL). The outcomes changes (Lungtest Handy) from baseline immediately after 8-week intervention. Parameters measured included forced expiratory volume 1 s (FEV 1), vital capacity (FVC), (VC). Results: After intervention, there significant difference (p<0.01) between AQUA LAND groups compared CONTROL for FEV values (F (2,64) = 6.80; P 0.91; p<0.01, η2 0.18), differences (p<0.05) (F(2,64) 6.96; 0.18). Repetitions-Groups interactions 1/%FVC 0.71, 0.162, p>0.05,η2 0.030) showed that occurred varied reason this an upward trend downward CONTROL. Conclusion: found supervised twice weekly training program water land improved

Язык: Английский

Процитировано

0

Post-COVID syndrome in pediatric practice: data from literature and clinical case DOI Creative Commons
Mariana Iskiv, N.S. Lukyanenko, N.R. Kech

и другие.

CHILD`S HEALTH, Год журнала: 2024, Номер 19(5), С. 316 - 322

Опубликована: Сен. 24, 2024

Background. An urgent and problematic issue in medicine today, addition to the acute manifestation of severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, are consequences disease 2019 (COVID-19), so-called post-COVID (PCS). Currently, leading medical research institutions around world studying causes, frequency symptoms PCS both adults children. Aim: review literature on incidence manifestations children order draw attention professionals problem its from various body systems. Materials ­methods. The search was conducted PubMed Google Scholar databases using following keywords: “SARS-CoV-2 or COVID-19” “post-COVID”, “long COVID”, “diabetes mellitus” “in children”. Ukrainian database authors article reviewed titles abstracts found articles select relevant publications. ­Results. provides data children: definition children, incidence, possible pathogenesis risk factors for development PCS. Signs somatic, psychological endocrinological also given. greatest is paid onset type 1 diabetes mellitus (T1DM) after suffering ­COVID-19. It noted that T1DM pediatric population period has almost doubled, 0.043 versus 0.025 %. Global rate new cases 2020 grew 32.39 per 100,000 compared 19.73 2019. Probable causes ­COVID-19 direct cytolysis pancreatic β-cells affected by virus, autoimmune reaction. A clinical case a young child as provided. Conclusions. 1. with quite common. 2. can deve­lop not only COVID-19, but asymptomatic course. 3. Along most frequent somatic COVID-19 endocrinopathy may occur, such mellitus.

Язык: Английский

Процитировано

0

Standardized Approach to Pediatric Post-COVID Syndrome and Its Impact on Children and Adolescents: A Perspective From a Tertiary Center DOI
Samuel Kembou Nzalé, Anne Perrin, Cindy Soroken

и другие.

The Pediatric Infectious Disease Journal, Год журнала: 2024, Номер unknown

Опубликована: Окт. 23, 2024

Background: Pediatric post-COVID syndrome (pPCS) affects a notable number of children. This study aims to describe its clinical manifestations, biopsychosocial impact and management strategies. Methods: A prospective, single-center was conducted analyze data pPCS patients presenting our institution between May 2021 November 2022. Functional evaluated by assessing school absenteeism using the Adolescent Depression Rating Scale (ADRS), Quality Life Inventory (PedsQL) Fatigue Severity Scale. Results: Among 50 included [median age (interquartile range): 14.0 (12.9–15.8) years; females: 70%], most common symptoms were extreme fatigue (84%), exertion intolerance (82%), orthostatism (66%), dyspnea (66%) headache (66%); 25% had an abnormal Schellong test. Median range) ADRS, PedsQL scores 3.0 (1.0–5.0), 56% (49%–71%) 45.0 (32.0–53.0), respectively. Sixty percent experienced partial (34%) or complete (26%) absenteeism. The referrals specialized consultations child psychiatry (48%), pulmonology (46%), physiotherapy (36%) ear-nose-throat specialist (24%). Eighty typical form pPCS, whereas 20% presentation suggestive functional disorder triggered COVID-19. latter more frequent thoracic pain ( P = 0.012) pediatric neurology 0.01), gastroenterology 0.011), ophthalmology 0.037) 0.035), but less 0.014). School social withdrawal also in this group, with severe ADRS scores. Conclusion: is associated significant socio-educational burden that should be taken into account medical, educational care.

Язык: Английский

Процитировано

0

Kinder und Jugendliche mit Post-COVID-Syndrom: eine qualitative Studie zu Erfahrungen und Zufriedenheit mit der Versorgung in einem Modellprojekt in Bayern (Post-COVID Kids Bavaria) DOI Creative Commons
Susanne Brandstetter, Maja Pawellek, Chiara Rathgeb

и другие.

Zeitschrift für Evidenz Fortbildung und Qualität im Gesundheitswesen, Год журнала: 2024, Номер unknown

Опубликована: Окт. 1, 2024

Against the background of inadequate healthcare provision for children and adolescents with post-COVID-19 syndrome (PCS), a model project was initiated in Bavaria (PoCoKiBa: Post-COVID Kids Bavaria), offering specialized diagnostics care. The aim this study to explore describe experiences satisfaction PCS, as well their parents, provided project.

Язык: Английский

Процитировано

0

Perspective Chapter: Sequelae and Consequences of COVID-19 in the Paediatric Population DOI Creative Commons
Víctor Manuel Gutiérrez Gómez,

Lenin Ortiz-Ortega,

Beatriz X. Pasco-Velázquez

и другие.

IntechOpen eBooks, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 25, 2024

During the pandemic and in subsequent years, we observed that COVID-19 caused by SARS-CoV-2 virus affected paediatric population different ways. In certain groups of children adolescents, social isolation, changes family dynamics, increased exposure to technological screens diet, among others, have their development, education, emotional, physical aspects, including access immunizations, medical surveillance control. is considered a generally benign pathology children; however, some patients develop well-defined post-COVID-19 entities: multisystem inflammatory syndrome (MIS-C) long COVID. this chapter, review, relation population, effects confinement during its development consequences, forms clinical presentation entities MIS-C COVID, prevalence, pathophysiology, presentation, evolution, detection management recommendations.

Язык: Английский

Процитировано

0

Adolescents with Persistent Symptoms Following Acute SARS-CoV-2 Infection (Long-COVID): Symptom Profile, Clustering and Follow-Up Symptom Evaluation DOI Creative Commons
Marco Floridia, Danilo Buonsenso,

Laura Macculi

и другие.

Children, Год журнала: 2024, Номер 12(1), С. 28 - 28

Опубликована: Дек. 27, 2024

Background: Few studies have evaluated long-COVID in adolescents. Methods: Cohort study. Demographics, clinical data, and the presence of 30 symptoms were collected with a modified WHO form. Mean values compared by Student’s t test proportions chi-square or Fisher test, trends over time analysed using for trend. Potential risk factors independently associated persisting multivariable logistic regression model. Clustering cases was two-step automatic clustering. Results: A total 97 adolescents aged 12–17 (54.6% females, 45.4% males) evaluated. After mean interval 96 days (SD 52) from acute infection, number (2.8 overall) higher pre-Omicron (3.2 vs. 2.5 Omicron, p = 0.046) moderate/severe infections (4.2 2.7 mild, 0.023). Fatigue (62.9%) dyspnea (43.3%) most common symptoms, followed headache (28.9%), thoracic pain (22.7%), diarrhea (20.6%), palpitations/tachycardia (17.5%), articular (15.5%), difficult concentration (14.4%), muscle (12.4%), taste reduction (8.2%), smell fever (6.2%), skin disorders (5.2%). The symptom profile similar males females but showed significant differences that observed concurrently adults. 340 45.3% still presented persistence initial symptoms. Two clusters defined differed phase infection Conclusions: Long-COVID manifestations may differ those Polisymptomaticity predict long-term persistence.

Язык: Английский

Процитировано

0