Enantiomeric Discrimination in Insects: The Role of OBPs and ORs

Insects, Год журнала: 2022, Номер 13(4), С. 368 - 368

Опубликована: Апрель 8, 2022

Olfaction is a complex recognition process that critical for chemical communication in insects. Though some insect species are capable of discrimination between compounds structurally similar, little understood about how this high level arises. Some insects rely on discriminating enantiomers compound, demonstrating an ability highly selective recognition. The role two major peripheral olfactory proteins olfaction, i.e., odorant-binding (OBPs) and odorant receptors (ORs) has been extensively studied. OBPs ORs have variable capabilities, with found to display specialized binding capability, whilst others exhibit promiscuous activity. A deeper understanding odorant-protein interactions induce response relies further analysis such as structural studies. In review, we explore the potential specific recognition, specifically enantiomeric discrimination. We summarize state research into OBP OR function focus reported examples literature clear by these proteins.

Язык: Английский

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Orco mediates olfactory behavior and oviposition in the whitefly Bemisia tabaci

Pesticide Biochemistry and Physiology, Год журнала: 2024, Номер 199, С. 105773 - 105773

Опубликована: Янв. 21, 2024

Язык: Английский

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Olfactory receptor coexpression and co-option in the dengue mosquito

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Авг. 22, 2024

The olfactory sensory neurons of vinegar flies and mice tend to express a single ligand-specific receptor. While this ′one neuron-one receptor′ motif has long been expected apply broadly across insects, recent evidence suggests it may not extend mosquitoes. We sequenced analyzed the transcriptomes 46,000 from antennae dengue mosquito Aedes aegypti resolve all olfactory, thermosensory, hygrosensory neuron subtypes identify receptors expressed therein. find that half coexpress multiple receptors. However, coexpression occurs almost exclusively among genes same family—among odorant (ORs) or ionotropic (IRs). Coexpression ORs with IRs is exceedingly rare. Many coexpressed are duplicates. In other cases, recruitment co-option by placed these together in cells distant paralogs. Close examination data Drosophila reveal rare cases both phenomena, indicating systems two species fundamentally different, but instead fall at different locations along continuum likely encompass diverse insects.

Язык: Английский

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Chemical Ecology and Olfaction in Short-Horned Grasshoppers (Orthoptera: Acrididae)

Journal of Chemical Ecology, Год журнала: 2022, Номер 48(2), С. 121 - 140

Опубликована: Янв. 10, 2022

Язык: Английский

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Silencing the odorant receptor co-receptor impairs olfactory reception in a sensillum-specific manner in the cockroach

iScience, Год журнала: 2022, Номер 25(5), С. 104272 - 104272

Опубликована: Апрель 20, 2022

Insects detect odors via a large variety of odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs). The insect OR is heteromeric complex composed ligand-specific receptor and the co-receptor (ORco). In this study, we identified ORco gene cockroach, Periplaneta americana (PameORco), performed RNAi-based functional analysis PameORco. All OSNs basiconic sensilla PameORco received including sex pheromones. trichoid sensilla, PameORco-positive OSN was consistently paired with PameORco-negative tuned to acids. adult cockroaches injected dsRNA at nymphal stage, expression PameORco, odor receptions ORs, its central processing were strongly suppressed. These results provide new insights into molecular basis reception cockroach. long-lasting irreversible effects RNAi would be an effective method for controlling household pest.

Язык: Английский

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Exploring the intersection of biology and design for product innovations

CIRP Annals, Год журнала: 2023, Номер 72(2), С. 569 - 592

Опубликована: Янв. 1, 2023

Design, development, productization, and applications of advanced product concepts are pressing for higher multifunctionality, resilience, maximization available resources equitably to meet the growing continuing demands global customers. These have further accelerated during recent COVID-19 pandemic be a challenge. Engineering designs one most effective ways endow products with functions, sustainability. Biology, through millions years evolution, has met these acute requirements under severe resource environmental constraints. As manufacturing is reaching fundamental limits raw materials, labor, constraints in terms availability, accessibility, affordability, new approaches call action challenges. Understanding biology an attractive, novel, desired frontier learning implementation this action. This focus paper discussed examples convergence engineering design lessons learned applied from biology.

Язык: Английский

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Insect odorant receptor-based biosensors: Current status and prospects

Biotechnology Advances, Год журнала: 2021, Номер 53, С. 107840 - 107840

Опубликована: Окт. 1, 2021

Язык: Английский

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Taste and Smell: A Unifying Chemosensory Theory

The Quarterly Review of Biology, Год журнала: 2022, Номер 97(2), С. 69 - 94

Опубликована: Май 18, 2022

Since antiquity, the sense of smell (olfaction) is considered as a distance sense, just like sight and hearing. Conversely, taste (gustation) thought to operate by direct contact, similarly touch. With progress natural sciences, information at molecular, anatomical, neurobiological levels has also contributed taste-smell dichotomy, but much evidence inconsistent with sharp differentiation these two senses emerged, especially when considering species other than humans. In spite this, conflicting been interpreted so that it could conform traditional differentiation. As result, confirmation bias currently affecting scientific research on chemosensory systems hindering development satisfactory narrative evolution chemical communication across taxa. From this perspective, dichotomy loses its validity usefulness. We thus propose unification all modalities into single moving toward synthetic, complex, interconnected perspective gradual processes which vast variety chemicals have become signals are crucially important among within cells, organs, organisms in wide environmental conditions.

Язык: Английский

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Task-specific odorant receptor expression in worker antennae indicates that sensory filters regulate division of labor in ants

Communications Biology, Год журнала: 2023, Номер 6(1)

Опубликована: Окт. 2, 2023

Division of labor (DOL) is a characteristic trait insect societies, where tasks are generally performed by specialized individuals. Inside workers focus on brood or nest care, while others take risks foraging outside. Theory proposes that have different thresholds to perform certain when confronted with task-related stimuli, leading specialization and consequently DOL. Workers presumed vary in their response cues rather than how they perceive such information. Here, we test the hypothesis DOL instead stems from varying efficiency detect stimuli specific tasks. We use transcriptomics measure mRNA expression levels antennae brain nurses foragers ant Temnothorax longispinosus. find seven times as many genes be differentially expressed between behavioral phenotypes compared brain. Moreover, half all odorant receptors expressed, an overrepresentation 9-exon gene family upregulated nurses. Nurses thus apparently differ perception olfactory environment signals. Our study supports antennal sensory filters predispose specialize

Язык: Английский

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Olfactory receptors in Bactrocera species for sustainable fruit fly management: A review and future perspectives

Physiological Entomology, Год журнала: 2024, Номер 49(2), С. 67 - 90

Опубликована: Янв. 24, 2024

Abstract Molecular studies on odorant receptors (ORs), odorant‐binding proteins (OBPs) and the functioning of receptor pheromone signal transduction in fruit fly Bactrocera species have expanded exponentially during past few decades. OBPs contribute to sensing olfactory system (OS) via odorants through sensillum lymph. However, ORs, a family G‐protein‐coupled various other species, exhibit heightened responsiveness multiple chemical odours such as hormones, sensory stimuli neurotransmitters. The apparent mechanism involves combinatorial code encompassing both peripheral antennal lobe processing, facilitating reception sexual pheromones environmental cues. OS is specifically designed recognize process information from volatile signals, these signals play an important function flies. Insects rely chemicals navigate comprehend their surroundings. A mature insect composed two pairs sensillae‐covered palps, antennae primary appendages anterior head. It has been shown that chemosensory gene families odour perception. These include neuroreceptor families, OBPs, neuron membrane proteins. Additionally, there are three divergent chemoreceptors, namely ionotropic gustatory receptors. Methods based systematic biology, molecular biology bioinformatics tools rapidly emerged investigate communication systems provide new insights for management many agricultural pest. Several aromatic compounds, including semiochemicals pheromones, employed defend crops animals destructive flies invasive frugivorous species. To promote expansion cropping system, utilization phytochemical lures can be convenient sustainable agriculture production enhance food security. Hence, this review examined state art insects with focus pest identify semiochemical receptors, protein (CSRs), well practical applications biological control integrated highlighted.

Язык: Английский

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