Long-Term Outcomes in Survivors of Childhood Cancer: A 30-Year Experience From India
JCO Global Oncology,
Год журнала:
2022,
Номер
8
Опубликована: Ноя. 1, 2022
PURPOSE
Despite
an
increasing
number
of
survivors
childhood
cancer
(CCS)
in
low-
and
middle-income
countries,
survivorship
care
is
its
nascent
stages.
We
describe
the
spectrum
late
effects
seen,
challenges
faced,
lessons
learnt
over
three
decades
a
program
India.
METHODS
demographics
profile
all
CCS
enrolled
our
After
Completion
Treatment
Clinic
from
February
5,
1991
(inception)
to
4,
2021.
analyzed
trends
by
decade
diagnosis.
RESULTS
There
were
3,067
survivors,
median
age
was
18
years
(range,
3-57
years),
follow-up
11
2-46
years).
Two
thirds
(62.4%)
had
either
no
or
mild
effects,
480
(15.6%),
497
(16.2%),
162
(5.3%)
grades
2,
3,
4
with
67
deaths
reported.
Notable
chronic
viral
hepatitis
(7.8%),
thyroid
dysfunction
(7.5%),
other
endocrine
issues
(13.6%),
psychosocial
(57%),
neurocognitive
impairment
(4.1%),
metabolic
syndrome
(4%).
The
cumulative
incidence
severity
showed
consistent
decline
Twenty-two
percent
are
lost
follow-up.
CONCLUSION
Survivors
treated
on
contemporary
treatment
protocols
have
significantly
lower
side-effect
profile.
Attrition
long-term
significant
concerns.
Understanding
unique
establishing
holistic
support
system
go
long
way
ensuring
physical
mental
health
concerns
countries.
Язык: Английский
Factors impacting physical activity among post-treatment pediatric cancer survivors with overweight and obesity
European Journal of Pediatrics,
Год журнала:
2024,
Номер
183(7), С. 3129 - 3136
Опубликована: Апрель 26, 2024
Язык: Английский
Physiological Profile Assessment and Self-Measurement of Healthy Students through Remote Protocol during COVID-19 Lockdown
Journal of Functional Morphology and Kinesiology,
Год журнала:
2024,
Номер
9(3), С. 170 - 170
Опубликована: Сен. 19, 2024
:
The
COVID-19
pandemic
has
led
to
reduced
physical
activity
and
increased
sedentary
behaviors,
negatively
impacting
mental
health.
Engaging
in
at
home
during
quarantine
became
essential
counteracting
these
adverse
effects.
To
develop
appropriate
programs,
assessing
individuals'
fitness
levels
the
impact
of
inactivity
is
crucial.
This
study
aims
compare
motor
abilities-including
flexibility,
balance,
reaction
time,
cardiovascular
endurance,
lower
upper
limb
strength-assessed
both
in-person
remotely,
determine
accuracy
repeatability
self-administered
tests.
Язык: Английский
The Care of Childhood Cancer Survivors in India: Challenges and Solutions
Indian Journal of Medical and Paediatric Oncology,
Год журнала:
2023,
Номер
45(02), С. 167 - 172
Опубликована: Апрель 17, 2023
Abstract
Purpose
We
describe
the
challenges
faced
and
lessons
learnt
over
three
decades
of
a
childhood
cancer
survivorship
program
in
India.
Methods
provide
descriptive
analysis
barriers
running
this
program,
our
strategies
management,
detail
stages
development
holistic
support
system.
Results
The
profile
late
effects
cohort
survivors
is
notable
for
high
prevalence
psychosocial
issues
metabolic
syndrome.
Major
difficulties
were
transitioning
patients
to
care
attrition
follow-up,
which
overcome
an
extent
by
ensuring
constant
communication/rapport-building,
updated
databases,
peer
groups.
Collaborations
with
nonprofit
organizations
other
donors
have
enabled
financial,
psychosocial,
educational,
vocational
rehabilitation.
Conclusions
It
feasible
establish
sustain
large-volume
center
low-
medium-income
country.
Understanding
unique
spectrum
establishing
system
go
long
way
long-term
physical
mental
health
concerns
survivors.
Decentralization,
strong
national
networks,
capacity
building,
incorporation
sustainable
technology
should
be
priorities
care.
Язык: Английский
Impact of COVID-19 on Lifestyle Habits and Emotional State of Childhood Cancer Survivors and Their Parents
Nutrients,
Год журнала:
2023,
Номер
15(18), С. 3932 - 3932
Опубликована: Сен. 11, 2023
Objective:
The
COVID-19
pandemic
and
associated
social
distancing
measures
affected
the
physical
emotional
state
of
children
parents
worldwide.
Survivors
childhood
cancer
may
be
particularly
vulnerable
to
these
effects.
We
aimed
evaluate
lifestyle
habits
states
survivors
their
during
outbreak.
Methods:
Lifestyle
distress
were
assessed
in
43
(aged
8–21
years)
before
lockdown,
using
PROMIS
anxiety
depression
modules
“Mabat
Youth”
questionnaire.
Results:
Most
(80.5%)
reported
eating
more
family
meals
home
confinement
compared
usual
routine.
Patients’
activity
levels
did
not
change
significantly
confinement,
leisure-related
screen
time
nearly
doubled
(p
<
0.001),
sleep
duration
increased
=
0.006).
Anxiety
0.045)
0.02)
pre-pandemic
levels,
with
no
significant
changes
levels.
Conclusions:
Contrary
concerns
regarding
behaviors
improved,
increased,
remained
unchanged.
Still,
significantly.
Parents
higher
for
themselves
confinement.
Our
findings
assist
medical
psycho-social
teams
guiding
similar
circumstances
future.
Язык: Английский
Psychological distress of adolescent and young adult childhood cancer survivors in a South African cohort
Pediatric Blood & Cancer,
Год журнала:
2022,
Номер
70(2)
Опубликована: Ноя. 28, 2022
Abstract
Background
We
investigated
psychological
distress
in
a
South
African
childhood
cancer
survivor
(CCS)
cohort.
Methods
Adult
CCSs
treated
at
Tygerberg
Hospital,
Cape
Town,
completed
the
Brief
Symptom
Inventory‐18.
Internal
consistency
was
acceptable:
Cronbach's
alpha
values
were
0.91
(Global
Severity
Index
(GSI)),
0.85
(depression),
0.83
(somatization),
and
0.75
(anxiety).
compared
results
utilizing
different
case
rules
(GSI
T
scores
of
≥50,
≥57,
≥63)
for
identification
distress.
Results
Forty
(median
age
24
years;
median
follow‐up
period
16
years)
participated.
Most
(58%;
23
out
40)
school
or
tertiary
education,
unmarried
(90%;
36
40),
unemployed
(59.5%;
22
37).
The
diagnoses
included
hematological
malignancies
(65%;
26
solid
tumors
(35%;
14
40).
GSI
≥63,
≥50
identified
10%
(four
32.5%
(13
45%
(18
survivors
with
distress,
respectively.
Radiotherapy
(odds
ratio
(OR)
4.6;
p
=
.035),
presence
≥six
late
effects
(OR
7.5;
.026),
severe
6.6;
.024)
significant
risk
factors
score
≥57).
Follow‐up
11–20
years
7.3;
.034)
≥50.
Conclusion
This
CCS
cohort
had
higher
levels
≥57
than
reported
literature.
unemployed.
Significant
contributing
radiotherapy,
number
severity
effects,
period.
must
be
screened
Язык: Английский
Communication transforms the impact of the COVID‐19 pandemic on children with cancer and their families
Cancer Medicine,
Год журнала:
2023,
Номер
12(11), С. 12813 - 12826
Опубликована: Апрель 20, 2023
Abstract
Background
The
COVID‐19
pandemic
altered
healthcare
systems
globally,
causing
delays
in
care
delivery
and
increased
anxiety
among
patients
families.
This
study
examined
how
hospital
stakeholders
clinicians
perceived
the
global
impact
of
on
children
with
cancer
their
Methods
secondary
analysis
data
from
a
qualitative
consisting
19
focus
groups
conducted
8
languages
throughout
16
countries.
A
codebook
was
developed
novel
codes
derived
inductively
transcript
review.
In‐depth
focused
Results
Eight
themes
describing
families
were
identified
classified
into
three
domains:
contributing
factors
(
Policies,
Cancer
Treatment
Modifications,
Symptoms,
Beliefs
),
patient‐related
impacts
Quality
Care,
Psychosocial
impacts,
Reluctance
central
transformer
Communication
).
Participants
described
ability
communication
to
transform
effect
impacts.
valence
depended
quality
quantity
between
Conclusions
served
as
factor
impacting
whether
positively
or
negatively
affected
These
findings
emphasize
key
role
plays
delivering
patient‐centered
can
guide
future
development
communication‐centered
interventions
globally.
Язык: Английский
Supportive care in paediatric oncology during the pandemic: Lessons from a nationwide survey in India
Pediatric Blood & Cancer,
Год журнала:
2023,
Номер
70(7)
Опубликована: Март 25, 2023
Please
note:
The
publisher
is
not
responsible
for
the
content
or
functionality
of
any
supporting
information
supplied
by
authors.
Any
queries
(other
than
missing
content)
should
be
directed
to
corresponding
author
article.
Язык: Английский
Economic and Other Fields of Late Effects
Springer eBooks,
Год журнала:
2023,
Номер
unknown, С. 75 - 84
Опубликована: Янв. 1, 2023
Язык: Английский
Examining Demographic and Environmental Factors in Predicting the Perceived Impact of Cancer on Childhood and Adolescent Cancer Survivors
Опубликована: Июль 25, 2022
Cancer
survivors'
perceptions
on
how
cancer
has
impacted
their
lives
been
identified
as
a
"critical
predictor"
of
psychosocial
well-being
and
quality
life
outcomes.
Given
the
dramatic
increase
in
survival
rates
long-term
health
challenges,
well
survivorship
care
barriers,
this
study
focuses
special
attention
childhood
adolescent
survivors
is
guided
by
Tedeschi
Calhoun's
theory
posttraumatic
growth
Hammond's
distinctiveness.
This
aims
to
examine
influence
demographic
(i.e.,
age
at
diagnosis,
biological
sex,
race/ethnicity,
type
cancer)
environmental
factors
geographical
location
insurance
type),
interaction
effects
diagnosis
x
predicting
negative
impacts
(NIOC)
positive
(PIOC).
Study
findings
provide
insights
better
understand
differential
female
survivors,
those
residing
rural
locations
with
public
insurance.
Язык: Английский