Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Май 29, 2025

Synthetic cannabinoids, a novel class of highly toxic psychoactive substances with various disguised forms, have posed significant risks to public safety, and their weak reactivity presents substantial challenge for swift accurate analysis. In this work, we develop an optical probe equipped dual excited-state intramolecular proton transfer (ESIPT) sites that inhibit the through hydrogen bonding, facilitating specific detection MDMB-type synthetic cannabinoids. The can sensitively detect cannabinoids at 1.8 × 10-3 mg/mL, specifically recognizing them among 20 potential interferents rapid fluorescence response within 1.2 s, leading development portable, user-friendly sensor precise analysis these compounds in complex scenarios. Furthermore, study combines portable sensing chip advanced convolutional algorithm image processing, enabling differentiation six cannabinoid variants. This successfully detected target substance by creating ESIPT probe, thereby offering approach limited reactivity.

Язык: Английский