Springer eBooks, Год журнала: 2022, Номер unknown, С. 165 - 181
Опубликована: Дек. 7, 2022
Язык: Английский
General Hospital Psychiatry, Год журнала: 2024, Номер 87, С. 20 - 32
Опубликована: Янв. 21, 2024
Язык: Английский
Процитировано
4
Journal of Clinical Nursing, Год журнала: 2025, Номер unknown
Опубликована: Апрель 4, 2025
To identify whether cognitive appraisal and coping style have moderating mediating effects on the relationship between family resilience quality of life (QoL) in patients with acute leukaemia (AL). AL is a clonal aggressive haematological malignancy that requires long-term continuous therapy, which may negatively influence QoL. Family can be used as psychosocial resource enhance patients' processes This cross-sectional descriptive study was conducted among hospitalised from June 2022 to 2023. A performed following STROBE Statement. Convenience sampling present study, 286 were recruited five tertiary Grade hospitals Xi'an, China. The questionnaires included Functional Assessment Cancer Therapy-Leukemia (FACT-Leu), Cognitive Appraisal Health Scale (CAHS), Trait Coping Style Questionnaire (TCSQ) Hardiness Index (FHI). We SPSS 26.0 Hayes' PROCESS macro for data analyses path coefficients. QoL significantly positively correlated positive coping, appraisal. partially mediated Positive moderated relationships appraisal, results revealed association by this relationship. These findings are meaningful early interventions reduce risk distress improve population. Nurses should focus provide support respect their undergoing clinical chemotherapy Chinese medical facilities.
Язык: Английский
Процитировано
0
Journal of Neural Transmission, Год журнала: 2025, Номер unknown
Опубликована: Апрель 11, 2025
Abstract Treatment with levodopa, a precursor of dopamine (DA), to compensate for the loss endogenous DA in Parkinson’s disease (PD), has been success story over 50 years. However, late stages PD, progressive degeneration dopaminergic neurons and ongoing reduction concentrations make it increasingly difficult maintain normal-like function. Typically, higher doses levodopa are required, fluctuations striatal concentrations—reflecting timing pattern administrations—become more pronounced. These can include highs that induce involuntary movements (levodopa-induced dyskinesia, LID) or lows result insufficient suppression PD symptoms (“OFF” phases). The enhanced primarily arise from buffering capacity, resulting neurons, an increased reliance on levodopa-derived release as “false neurotransmitter” by serotonergic neurons. In many patients, LID OFF-phases be alleviated modifying therapy provide continuous delivery using additional medications, such monoamine oxidase-B (MAO-B) inhibitors, amantadine, receptor agonists. Understanding challenges faced also requires considering striatum is characterized not only but neuroplastic adaptations PD-induced degenerations other neural populations. This review provides broad overview use treating focus underlying science encountered disease.
Язык: Английский
Процитировано
0
The International Journal of Psychiatry in Medicine, Год журнала: 2025, Номер unknown
Опубликована: Апрель 21, 2025
Objective To explore the clinical effect of sertraline combined with psychological hotline-based Naikan therapy, a structured form self-reflection, in treatment adolescents depressive disorder. Hotline-based therapy is where telephone operators who have been trained this help address distress for callers through counselling. Methods A randomised controlled trial was conducted involving 93 adolescent outpatients disorder, 47 participants assigned to Combined group and 46 Sertraline group. Adolescents were treated only. received using at same dose as those group, therapy. Depression anxiety levels both groups evaluated Self-Rating Scale (SDS) Anxiety (SAS) baseline after 2nd, 4th 12th weeks treatment. Results There no significant differences between terms demographic or characteristics. Participants intervention reported serious adverse reactions. By end week treatment, between-group found SDS SAS scores, favouring (χ 2 = 6.68, P 0.010 χ 5.68, 0.017, respectively). Conclusion more effective reducing symptoms disorder than receiving alone.
Язык: Английский
Процитировано
0
World Journal of Psychiatry, Год журнала: 2024, Номер 14(7), С. 999 - 1008
Опубликована: Июль 11, 2024
Cognitive-behavioral therapy (CBT) and habit reversal training (HRT) have shown application potential in addressing tic symptoms comorbid psychiatric conditions. Despite their theoretical potential, empirical evidence on combined efficacy remains limited.
Язык: Английский
Процитировано
1
Therapeutic Advances in Gastroenterology, Год журнала: 2024, Номер 17
Опубликована: Янв. 1, 2024
The prevalence of anxiety, depression, and other psychological comorbidities among patients with inflammatory bowel disease (IBD) significantly exceeds that the general population. Moreover, a bidirectional relationship exists between IBD. This intricate interplay has substantial clinical implications, impacting treatment adherence, therapeutic efficacy, recurrence rates. In this review, we explore multifaceted mechanisms through which factors influence IBD progression, response, prognosis. Specifically, delve into involvement hypothalamic-pituitary-adrenal axis, autonomic nervous system, enteric microbiota-gut-brain systemic cytokines, immune cell function. Additionally, discuss potential benefits antidepressant therapy in mitigating risk role psychotropic drugs reducing peripheral inflammation. Recognizing addressing comorbidity is pivotal comprehensive management. We advocate for integration biopsychosocial approaches strategies, emphasizing need innovative interventions as adjuncts to conventional therapies. Rigorous research investigating impact antidepressants behavioral on IBD-specific outcomes may herald paradigm shift
Язык: Английский
Процитировано
1
Current Psychology, Год журнала: 2024, Номер 43(32), С. 26673 - 26690
Опубликована: Апрель 29, 2024
Язык: Английский
Процитировано
0
Journal of Neural Transmission, Год журнала: 2023, Номер 130(8), С. 1077 - 1088
Опубликована: Май 5, 2023
Язык: Английский
Процитировано
1
Springer eBooks, Год журнала: 2022, Номер unknown, С. 165 - 181
Опубликована: Дек. 7, 2022
Язык: Английский
Процитировано
0