Causal Associations of Insomnia and Postpartum Depression: A Two-Sample Mendelian Randomization Study DOI Creative Commons
Xiao Shen,

Dongyan Qiao,

Yixiao Wang

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Авг. 18, 2023

Abstract Background Postpartum depression (PPD), a prevalent social mental condition, impacts not only the mother and newborn but also several facets of their lives. It has been suggested that insomnia is related to both occurrence progression PPD. However, because lingering confounding bias, it impossible determine cause this connection using observational analysis. In study, we evaluate causal importance on postpartum Mendelian randomization (MR). Methods Utilizing summary data from genome-wide association studies (GWAS), two-sample MR study was conducted. A GWAS dataset IEU United Kingdom Biobank phenotypes comprising 462,341 people European heritage yielded 38 single-nucleotide polymorphisms (SNPs) for insomnia. The PPD were provided by FinnGen project comprised 7604 cases 59601 controls. Inverse variance weighting (IVW) utilized primary analysis, with weighted median MR-Egger serving as sensitivity analyses. Results As result, found genetically predicted positively associated depression. odds ratios (OR) 1.849 (95% (confidence interval) CI: 1.011–3.381; p = 0.046). Conclusion For first time, causative role sleeplessness extensively evaluated in current investigation. Our findings show are way.

Язык: Английский

Impact of pre-pregnancy and pregnancy sleep on the risk of postpartum depression in the Japan Environment and Children’s Study DOI
Yoshiko Suetsugu, Takehiro Michikawa, Seiichi Morokuma

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Июль 1, 2024

Abstract This study aimed to determine the longitudinal effects of pre-pregnancy and pregnancy sleep on maternal depression at one month postpartum, stratified by parity. We used data from Japan Environment Children’s Study, a cohort that registered 103,060 pregnancies between 2011 2014. A total 76,977 women were included in this asked about their during pregnancy, whether they had postpartum depression. found those who slept 8–9 hours slightly lower odds compared with 7–8 (odds ratio OR = 0.92, 95% confidence interval CI:0.87–0.99), bedtimes other than 9 p.m. 3 a.m. increased midnight (OR 1.14, CI:1.00–1.31). During less 6 whose bedtime was ORs 1.21, CI:1.09–1.31; 1.25, CI:1.08–1.45, respectively). Poor quality To prevent depression, it is important for have good pre-pregnancy.

Язык: Английский

Процитировано

0
A longitudinal network analysis of interaction factors among Chinese women at high risk for perinatal depression DOI
Jun Huang, Yiyang Lin,

Yanqing Fu

и другие.

Midwifery, Год журнала: 2024, Номер 139, С. 104187 - 104187

Опубликована: Сен. 18, 2024

Язык: Английский

Процитировано

0
Genetical effects of sleep traits on postpartum depression: a bidirectional two-sample Mendelian randomization study DOI Creative Commons
Qianying Hu,

Enzhao Cong,

Jianhua Chen

и другие.

BMC Pregnancy and Childbirth, Год журнала: 2024, Номер 24(1)

Опубликована: Окт. 30, 2024

Язык: Английский

Процитировано

0
A latent class analysis of co-occurring insomnia and anxiety among Chinese pregnant women DOI Creative Commons

ShanYan Liu,

Meijiao Huang,

Jing Tao

и другие.

Journal of Psychosomatic Obstetrics & Gynecology, Год журнала: 2024, Номер 45(1)

Опубликована: Дек. 2, 2024

Currently, there remains a paucity of comprehensive evidence concerning the concurrent presence insomnia and anxiety in pregnant women. This study, employing convenience sampling, enrolled 1049 Chinese Key assessment instruments comprised three-item Insomnia Symptoms scale, two-item Generalized Anxiety Disorder Scale, as well measures demographic pregnancy-specific characteristics. The findings revealed that prevalence symptoms among participants was 54.5% 18.8%, respectively. Considering heterogeneous patterns co-occurring anxiety, 30% women experienced high with moderate while 70% mild anxiety. study found educational level, trimester, miscarriage history, pregnancy complications pregnancy-related anemia significantly affected provides clinical advice for reducing sleep disorders

Язык: Английский

Процитировано

0
Causal Associations of Insomnia and Postpartum Depression: A Two-Sample Mendelian Randomization Study DOI Creative Commons
Xiao Shen,

Dongyan Qiao,

Yixiao Wang

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Авг. 18, 2023

Abstract Background Postpartum depression (PPD), a prevalent social mental condition, impacts not only the mother and newborn but also several facets of their lives. It has been suggested that insomnia is related to both occurrence progression PPD. However, because lingering confounding bias, it impossible determine cause this connection using observational analysis. In study, we evaluate causal importance on postpartum Mendelian randomization (MR). Methods Utilizing summary data from genome-wide association studies (GWAS), two-sample MR study was conducted. A GWAS dataset IEU United Kingdom Biobank phenotypes comprising 462,341 people European heritage yielded 38 single-nucleotide polymorphisms (SNPs) for insomnia. The PPD were provided by FinnGen project comprised 7604 cases 59601 controls. Inverse variance weighting (IVW) utilized primary analysis, with weighted median MR-Egger serving as sensitivity analyses. Results As result, found genetically predicted positively associated depression. odds ratios (OR) 1.849 (95% (confidence interval) CI: 1.011–3.381; p = 0.046). Conclusion For first time, causative role sleeplessness extensively evaluated in current investigation. Our findings show are way.

Язык: Английский

Процитировано

1