Advances in Tumor Management: Harnessing the Potential of Histotripsy

Radiology Imaging Cancer, Год журнала: 2024, Номер 6(3)

Опубликована: Апрель 19, 2024

Tissue ablation techniques have long been used in clinical settings to treat various oncologic diseases. However, many of these are invasive and can cause substantial adverse effects. Histotripsy is a noninvasive, nonionizing, nonthermal tissue technique that has the potential replace surgical interventions settings. works by delivering high-intensity focused ultrasound waves target tissue. These create cavitation bubbles within tissues rapidly expand collapse, thereby mechanically fractionating into acellular debris subsequently absorbed body's immune system. Preclinical studies demonstrated efficacy histotripsy treating range diseases, including liver, pancreatic, renal, prostate tumors. Safety outcomes generally favorable, with minimal effects reported. further needed optimize understand its long-term This review aims discuss importance as noninvasive technique, preclinical literature on safety, applications practice.

Язык: Английский

Overcoming the Blood-Brain Barrier: Focused Ultrasound in Glioblastoma Treatment

Cureus, Год журнала: 2025, Номер unknown

Опубликована: Апрель 23, 2025

Язык: Английский