npj Materials Degradation,
Год журнала:
2024,
Номер
8(1)
Опубликована: Фев. 3, 2024
Abstract
It
is
known
that
network
modifying
ions
(such
as
alkali
or
alkaline
earth
ions)
make
glasses
susceptible
to
aqueous
corrosion,
resulting
in
the
alteration
of
their
surface
layers.
However,
effect
altered
layers
on
mechanical
properties
has
not
been
well
understood.
In
this
work
we
study
using
pharmaceutical
boroaluminosilicate
(BAS)
objects
by
performing
nano-
and
macroscale
tests.
The
results
show
extending
corrosion
time
increases
thickness
layer
BAS
glass.
water-related
species
lowers
nanohardness,
reduced
modulus,
nanowear
resistance
Vickers
hardness.
corrosion-induced
“silica-like”
structure
benefits
densification
subsurface
caused
nanoindentation
nanowear,
thereby
enhances
fracture
toughness
correlation
between
water
content
revealed.
This
instrumental
design
next
generation
with
higher
toughness.
ACS Materials Au,
Год журнала:
2023,
Номер
3(6), С. 600 - 619
Опубликована: Авг. 21, 2023
Over
the
past
decade,
therapeutic
potential
of
nanomaterials
as
novel
drug
delivery
systems
complementing
conventional
pharmacology
has
been
widely
acknowledged.
Among
these
nanomaterials,
lipid-based
nanoparticles
(LNPs)
have
shown
remarkable
pharmacological
performance
and
promising
outcomes,
thus
gaining
substantial
interest
in
preclinical
clinical
research.
In
this
review,
we
introduce
main
types
LNPs
used
formulations
such
liposomes,
nanoemulsions,
solid
lipid
nanoparticles,
nanostructured
carriers,
polymer
hybrid
focusing
on
their
physicochemical
properties
potential.
We
discuss
computational
studies
modeling
techniques
to
enhance
understanding
how
interact
with
cargo
predict
effectiveness
interactions
applications.
also
analyze
benefits
drawbacks
various
LNP
production
nanoprecipitation,
emulsification,
evaporation,
thin
film
hydration,
microfluidic-based
methods,
an
impingement
jet
mixer.
Additionally,
major
challenges
associated
industrial
development,
including
stability
sterilization,
storage,
regulatory
compliance,
reproducibility,
quality
control.
Overcoming
facilitating
compliance
represent
key
steps
toward
LNP's
successful
commercialization
translation
into
settings.
ACS Nano,
Год журнала:
2023,
Номер
17(11), С. 10269 - 10279
Опубликована: Май 31, 2023
Vaccines
are
undoubtedly
a
powerful
weapon
in
our
fight
against
global
pandemics,
as
demonstrated
the
recent
COVID-19
case,
yet
they
often
face
significant
challenges
reliable
cold
chain
transport.
Despite
extensive
efforts
to
monitor
their
time–temperature
history,
current
indicators
(TTIs)
suffer
from
limited
reliability
and
stability,
such
difficulty
avoiding
human
intervention,
inapplicable
subzero
temperatures,
narrow
tracking
temperature
ranges,
or
susceptibility
photobleaching.
Herein,
we
develop
class
of
structural
color
materials
that
harnesses
dual
merits
fluidic
nature
color,
enabling
thermal-triggered
visible
destruction
based
on
triggering
agent-diffusion-induced
irreversible
disassembly
liquid
colloidal
photonic
crystals
for
indicating
history
These
self-destructive
liquids
(SCLs)
exhibit
inherent
irreversibility,
superior
sensitivity,
tunable
time
(minutes
days),
wide
range
(−70
+37
°C).
Such
SCLs
can
be
conveniently
packaged
into
flexible
TTIs
monitoring
storage
exposure
status
diverse
vaccines
via
naked-eye
inspection
mobile
phone
scanning.
By
overcoming
shortcomings
conventional
responsive
crystals,
these
increase
compatibility
with
transport
hold
promise
development
application
next-generation
intelligent
crystals.
Energy Reports,
Год журнала:
2021,
Номер
8, С. 955 - 972
Опубликована: Дек. 24, 2021
The
outbreaks
of
infectious
diseases
that
spread
across
countries
have
generally
existed
for
centuries.
An
example
is
the
occurrence
COVID-19
pandemic
in
2020,
which
led
to
loss
lives
and
economic
depreciation.
One
essential
ways
handling
viruses
discovery
administration
vaccines.
However,
major
challenges
vaccination
programs
are
associated
with
vaccine
cold
chain
management
storage
facilities.
This
paper
discusses
how
technology
can
address
programs.
Specifically,
it
examines
different
systems
preserving
vaccines
either
liquid
or
frozen
form
help
ensure
they
not
damaged
during
distribution
from
manufacturing
Furthermore,
A
likely
provide
very
low
efficacy
when
properly
stored.
According
preliminary
studies,
inability
store
partly
due
incompetency
many
stakeholders,
especially
technical
matters.
novelty
this
study
thoroughly
explore
a
faster
more
comprehensive
hence
expected
be
one
reference
inspiration
stakeholders.
Comprehensive Reviews in Food Science and Food Safety,
Год журнала:
2022,
Номер
21(3), С. 2615 - 2638
Опубликована: Март 12, 2022
Abstract
The
fourth
industrial
revolution
(I4.0)
intends
to
digitalize
the
product
life
cycle
using
smart
technologies
interconnected
with
web‐based
platforms.
I4.0
elements
can
be
employed
enable
packaging
4.0
improved
productivity
and
efficiency.
However,
applicability
of
in
science
has
not
been
fully
investigated
due
understanding
gap
regarding
science.
In
addition,
evolution
market
customers’
demands
results
complexity,
which
requires
a
business
model
high
level
precision.
As
stays
goods
from
manufacturing
consumer
stage,
digitalization
realized.
Herein,
implications
on
are
discussed
identify
potential
benefits
various
sectors,
for
example,
manufacturing,
materials,
supply
chain,
retail,
postconsumer.
this
study,
is
defined
based
framework
comprised
products,
consumer,
sustainability
(ecologically,
economically,
socially).
decentralized
introduced
realize
self‐controlling
concept
decision‐making
centers.
context,
enabled
combination
horizontal
integration
enterprises,
vertical
end‐to‐end
engineering.
Smart
devices,
sensors,
indicators,
actuators,
wearable
internet
things
cloud
an
efficient
way
paradigm.
implementation
intelligent
platform
context
enables
data
collection
in‐store,
postpurchasing
stages,
turn
realizes
consistent
life‐cycle
monitoring.
