Endocrine-disrupting
chemicals
(EDCs)
are
widespread
environmental
contaminants
that
interfere
with
hormonal
regulation,
affecting
metabolism,
reproduction,
neurodevelopment,
and
overall
health.
This
review
presents
an
overview
of
recent
evidence
on
the
health
effects
biological
mechanisms
EDCs,
a
focus
their
impact
balance
quality
life.
An
integrative
literature
was
conducted
using
28
peer-reviewed
articles
published
between
2020
2025,
retrieved
from
databases
such
as
PubMed,
Scopus,
ScienceDirect.
The
selected
studies
explored
physiological
pathological
EDCs
in
humans.
Compounds,
bisphenol
A,
phthalates,
polychlorinated
biphenyls
(PCBs),
can
mimic
or
block
hormones,
disrupt
endocrine
signaling
pathways,
bioaccumulate
tissues.
Exposure,
especially
during
critical
developmental
windows,
is
linked
to
metabolic
disorders,
infertility,
neurodevelopmental
delays,
hormone-sensitive
cancers.
Common
exposure
sources
include
food,
air,
household
dust,
water,
personal
care
products.
Key
action
involve
receptor
binding
interference,
oxidative
stress,
epigenetic
alterations.
pose
significant
growing
threat
public
health,
warranting
urgent
regulatory
measures,
increased
awareness,
continued
research
mitigate
long-term
consequences.
Phytotherapy Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 24, 2025
ABSTRACT
The
human
body
gets
exposed
to
a
variety
of
toxins
intentionally
or
unintentionally
on
regular
basis
from
sources
such
as
air,
water,
food,
and
soil.
Certain
can
be
synthetic,
while
some
are
biological.
affect
the
various
parts
by
activating
numerous
pro‐inflammatory
markers,
like
oxidative
stresses,
that
tend
disturb
normal
function
organs
ultimately.
Nowadays,
people
use
different
types
herbal
treatments,
viz.,
drinks
contain
spices
for
detoxification
their
bodies.
One
example
is
turmeric,
most
commonly
available
spice
in
kitchen
used
across
all
kinds
households.
Turmeric
contains
curcumin,
which
natural
polyphenol.
Curcumin
medicinal
compound
with
biological
activities,
antioxidant,
antineoplastic,
anti‐inflammatory,
antibacterial.
Hence,
this
review
gives
comprehensive
insight
into
promising
potential
curcumin
heavy
metals,
carbon
tetrachloride,
drugs,
alcohol,
acrylamide,
mycotoxins,
nicotine,
plastics.
encompasses
diverse
animal‐based
studies
portraying
curcumin's
role
nullifying
toxic
effects
(especially
liver,
kidney,
testicles,
brain)
enhancing
defensive
signaling
pathways,
improving
antioxidant
enzyme
levels,
inhibiting
markers
activities
so
on.
Furthermore,
also
argues
over
safety
assessment
its
utilization
detoxifying
agent.
Molecules,
Год журнала:
2025,
Номер
30(3), С. 628 - 628
Опубликована: Янв. 31, 2025
In
this
study,
Fe3O4
was
used
as
a
magnetic
core,
combined
with
the
characteristics
of
mesoporous
adsorbents,
to
prepare
novel
composite
material
named
MMC.
Cetyltrimethylammonium
bromide
(CTAB)
and
tetraethyl
orthosilicate
(TEOS)
were
functional
monomers,
simple
etching
method
employed.
The
resulting
MMC
an
effective
adsorbent
for
solid-phase
extraction
trace
residues
six
bisphenol
endocrine
disruptors
(bisphenol
A,
B,
C,
F,
AF,
AP)
from
environmental
water
food
samples.
Characterization
results
indicated
that
surface
exhibited
distinct
wormhole-like
structure,
successful
incorporation
CTAB
groups
Si-OH.
crystal
structure
remained
stable
throughout
preparation
process.
Mapping
analysis
confirmed
uniform
distribution
without
aggregation
demonstrated
high
intensity,
enabling
rapid
separation
collection
under
external
field.
Extraction
elution
conditions
optimized,
tests
conducted
interfering
substances
such
humic
acid,
glucose,
fructose,
sucrose
optimal
parameters.
showed
recovery
rates
not
significantly
affected.
quality
evaluation
good
linearity,
broad
linear
range,
low
limits
detection
quantification,
satisfactory
rates.
Blank
spiked
analyses
seven
real
samples,
including
(rivers
lakes)
samples
(dairy,
juice,
carbonated
beverages),
achieved.
Thus,
developed
analytical
enables
various
pollutants
in
complex
matrices,
providing
valuable
reference
similar
contaminants
matrices.
ACS ES&T Water,
Год журнала:
2024,
Номер
4(4), С. 1531 - 1545
Опубликована: Фев. 26, 2024
This
study
investigated
the
occurrence
and
concentration
of
emerging
persistent
contaminants
(EPC)
within
a
variety
land
uses
in
Ping
River
catchment
northern
Thailand.
Urban
sites
exhibited
highest
levels
contamination,
followed
by
agriculture
rural
sites.
The
high
presence
pharmaceuticals,
daily
use
compounds,
industrial-related
compounds
urban
areas
indicates
significant
contributions
wastewater
likely
associated
with
drainage
from
manufacturing,
repair,
medical
activities,
as
well
dense
residential
living.
ubiquitous
(caffeine
acesulfame)
all
land-use
types
was
an
indicator
gray
water
pollution
catchment.
Seasonal
variations
EPC
were
not
significant,
possibly
due
to
constant
mixing
or
flushing
EPCs
large
through
multiple
flow
pathways.
complexity
mixed-use
dependent
on
factors
related
usage
processes,
both
natural
anthropogenic,
that
affect
entry
into
environment
sources
then
river
system
and,
potentially,
groundwater.
findings
highlight
heterogeneity
dynamic
nature
anthropogenic
landscapes
emphasize
need
for
further
research
influence
hydrological
connectivity
intensity
such
settings.
