Present status and application prospects of green chitin nanowhiskers: A comprehensive review
International Journal of Biological Macromolecules,
Год журнала:
2024,
Номер
278, С. 134235 - 134235
Опубликована: Июль 29, 2024
Язык: Английский
Phytotherapeutic Hierarchical PCL‐Based Scaffolds as a Multifunctional Wound Dressing: Combining 3D Printing and Electrospinning
Macromolecular Bioscience,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 10, 2024
Abstract
This
study
focuses
on
developing
hybrid
scaffolds
incorporating
phytotherapeutic
agents
via
a
combination
of
three‐dimensional
(3D)
printing
and
electrospinning
to
enhance
mechanical
properties
provide
antibacterial
activity,
in
order
address
the
limitations
traditional
antibiotics.
In
this
regard,
3D‐printed
polycaprolactone
(PCL)
struts
are
first
fabricated
using
fused
deposition
modeling
(FDM).
Then,
alkaline
surface
treatment
is
applied
improve
adhesion
electrospun
nanofibers.
Finally,
peppermint
oil
(PEP)
or
clove
(CLV)‐incorporated
PCL‐gelatin
(GEL)
nanofibers
collected
top
PCL
by
electrospinning.
Incorporating
PEP
CLV
into
PCL‐GEL
enhances
scaffold's
layer
detachment
force.
addition,
DPPH
free
radical
scavenging
activity
assay
indicates
that
improves
antioxidant
scaffolds.
Further,
results
reveal
incorporated
exhibit
inhibition
against
Staphylococcus
aureus
Escherichia
coli
bacteria.
Moreover,
anti‐inflammatory
assays
show
reduce
concentration
nitric
oxide
(NO)
released
from
Raw
264.7
macrophage‐like
cells.
On
other
hand,
hierarchical
have
no
toxic
effect
normal
human
dermal
fibroblast
(NHDF)
cells,
cell
attachment
proliferation.
Overall,
natural
shows
promise
for
advancing
wound
healing
applications.
Язык: Английский
Development of Functionalized Poly(ε-caprolactone)/Hydroxyapatite Scaffolds via Electrospinning 3D for Enhanced Bone Regeneration
ACS Omega,
Год журнала:
2024,
Номер
9(45), С. 45035 - 45046
Опубликована: Окт. 30, 2024
Functionalized
scaffolds
based
on
biodegradable
polymers
are
materials
used
in
bone
tissue
engineering.
This
study
presents
the
development
of
functionalized
fibrous
scaffolds,
fabricated
from
poly(ε-caprolactone)
(PCL)
and
hydroxyapatite
(HA).
To
produce
this
material,
a
short-distance
electrospinning
(ES)
system
was
developed
by
adapting
3D
printer.
The
morphology
chemical
properties
were
evaluated
using
scanning
electron
microscopy,
X-ray
diffraction,
Fourier-transform
infrared
spectroscopy,
thermogravimetric
analysis.
results
confirmed
porous
structure
presence
throughout
entire
scaffold
area.
Mechanical
tests
indicated
good
elasticity
tensile
strength
favorable
for
regeneration.
In
vitro
showed
high
levels
cell
viability.
Furthermore,
vivo
experiments
calvarial
defect
model
rats
demonstrated
that
PCL/HA
promoted
enhanced
Therefore,
through
adapted
shows
promise
repair.
Язык: Английский