COVID-19 Vaccination and Transient Increase in CD4/CD8 Cell Counts in People with HIV: Evidence from China DOI Creative Commons
Yanyan Li,

Yingying Lin,

Yunyun Yi

и другие.

Vaccines, Год журнала: 2024, Номер 12(12), С. 1365 - 1365

Опубликована: Дек. 3, 2024

Objectives: Accumulating evidence has confirmed the efficacy and safety of COVID-19 vaccines against SARS-CoV-2 infection. However, effect vaccination on immuno-virological parameters in people with HIV (PWH) is uncertain. Methods: A total 372 PWH treated at Beijing Ditan Hospital were included. Unvaccinated matched 1:3 vaccinated using a propensity score matching algorithm. Differences markers between groups analyzed. The Wilcoxon signed rank test was used to for changes CD4 CD8 counts viral load over two months around vaccination. In addition, we investigated long-term HIV-related different dose entire population. Results: Vaccinated had higher CD4/CD8 ratio (0.64 (0.49, 0.78) vs. 0.80 (0.56, 1.03), p = 0.037) than unvaccinated within two-month window after third dose. There 337 who received vaccination, 73.9% (n 249) three doses vaccine. We observed transient increase count especially second (CD4 count: 583.5 (428.5, 706.8) 618.0 (452.0, 744.0), 0.018; ratio: 0.70 (0.50, 0.91) 0.71 (0.53, 0.96), < 0.001)) 575.5 (435.5, 717.0) 577.5 (440.8, 754.8), 0.001; (0.52, 0.93) 0.79 1.00), 0.001)). Recent ratios lower but remained before PWH. no negative load. Conclusions: enhanced cellular immune response induced by may diminish time return normal levels. adverse

Язык: Английский

Update on Vaccination Recommendations for Adults with HIV DOI

Fiona Gispen,

Kristen Marks

Current HIV/AIDS Reports, Год журнала: 2025, Номер 22(1)

Опубликована: Фев. 20, 2025

Язык: Английский

Процитировано

0

“I’m Afraid to Put Any More of It Into My Body”: COVID-19 Vaccination and Booster Barriers and Facilitators Among People with HIV in South Carolina DOI Creative Commons
Camryn Garrett, Arielle N’Diaye, Shan Qiao

и другие.

AIDS and Behavior, Год журнала: 2025, Номер unknown

Опубликована: Март 3, 2025

Язык: Английский

Процитировано

0

Navigating Coronavirus Disease 2019 in Immunocompromised Populations DOI
Majd Alsoubani, Jennifer Chow

Infectious Disease Clinics of North America, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Determinants of COVID-19 Vaccine Uptake Among People Living with Human Immunodeficiency Virus DOI Creative Commons
Gaukhar Mergenova, Alissa Davis, Susan L. Rosenthal

и другие.

Journal of the International Association of Providers of AIDS Care (JIAPAC), Год журнала: 2025, Номер 24

Опубликована: Апрель 1, 2025

Background Human immunodeficiency virus (HIV) cases are rising in Central Asia and Kazakhstan. People living with HIV (PLWH) Kazakhstan at heightened risk of severe COVID-19. We conducted a study to evaluate determinants COVID-19 vaccine uptake among PLWH Methods In this cross-sectional study, 196 were recruited from the Almaty City AIDS Center (July 2022-January 2023). used logistic regression how multilevel factors associated Results non-uptake was higher stigma scores (AOR = 1.08, 95%CI:1.02,1.16, P 0.017), lower level education 2.53, 95%CI: 1.04,6.17, 0.0412), never receiving flu 15.64, 95%CI:3.66,66.89, 0.0002). Participants least mild anxiety symptoms 0.15, 95%CI:0.03,0.64, 0.0107) positive attitude towards vaccination 0.79, 0.73,0.86, < 0.0001) less likely remain unvaccinated against Conclusions campaigns should be tailored for incorporate reduction interventions within healthcare settings.

Язык: Английский

Процитировано

0

Factors Associated with Vaccination Adequacy in People Living with HIV: A Cross-Sectional Study DOI Creative Commons
Larissa Gerin, Andrey Oeiras Pedroso, Marcela Antonini

и другие.

Vaccines, Год журнала: 2024, Номер 12(9), С. 1003 - 1003

Опубликована: Сен. 1, 2024

People living with HIV (PLHIV) are at greater risk of illness and death from vaccine-preventable diseases. This study aimed to identify the predictors associated recommended vaccination schedule for this group. was a single-center cross-sectional conducted in large Brazilian municipality, evaluating statuses 645 PLHIV nine immunizers. The primary outcome adequacy schedule. status assessed diphtheria/tetanus, hepatitis B, A, measles/mumps/rubella, yellow fever, 13- 23-valent pneumococcal, meningococcal C, HPV vaccines. Those who had received all vaccinations accordance established by government time assessment, without any delays, were classified as having an “adequate schedule”. independent variables included sociodemographic, clinical–epidemiological, social vulnerability factors, analyzed multiple logistic regression adjusted odds ratios (ORs) 95% confidence intervals (95% CIs). Only 47 individuals (7.3%) adequate vaccines highest rate diphtheria tetanus (533; 82.6%), one lowest measles/mumps/rubella (MMR) (243; 37.7%). main complete age group, place clinical follow-up, where they their last doses Educational interventions health professionals needed improve coverage

Язык: Английский

Процитировано

0

COVID-19 Vaccination and Transient Increase in CD4/CD8 Cell Counts in People with HIV: Evidence from China DOI Creative Commons
Yanyan Li,

Yingying Lin,

Yunyun Yi

и другие.

Vaccines, Год журнала: 2024, Номер 12(12), С. 1365 - 1365

Опубликована: Дек. 3, 2024

Objectives: Accumulating evidence has confirmed the efficacy and safety of COVID-19 vaccines against SARS-CoV-2 infection. However, effect vaccination on immuno-virological parameters in people with HIV (PWH) is uncertain. Methods: A total 372 PWH treated at Beijing Ditan Hospital were included. Unvaccinated matched 1:3 vaccinated using a propensity score matching algorithm. Differences markers between groups analyzed. The Wilcoxon signed rank test was used to for changes CD4 CD8 counts viral load over two months around vaccination. In addition, we investigated long-term HIV-related different dose entire population. Results: Vaccinated had higher CD4/CD8 ratio (0.64 (0.49, 0.78) vs. 0.80 (0.56, 1.03), p = 0.037) than unvaccinated within two-month window after third dose. There 337 who received vaccination, 73.9% (n 249) three doses vaccine. We observed transient increase count especially second (CD4 count: 583.5 (428.5, 706.8) 618.0 (452.0, 744.0), 0.018; ratio: 0.70 (0.50, 0.91) 0.71 (0.53, 0.96), < 0.001)) 575.5 (435.5, 717.0) 577.5 (440.8, 754.8), 0.001; (0.52, 0.93) 0.79 1.00), 0.001)). Recent ratios lower but remained before PWH. no negative load. Conclusions: enhanced cellular immune response induced by may diminish time return normal levels. adverse

Язык: Английский

Процитировано

0