Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Апрель 8, 2025

Bone tumor organoids are three-dimensional cell culture models derived from patient tissues or cells, capable of highly replicating the growth patterns and interactions bone tumors in vitro . Current treatments for hindered by challenges such as drug resistance, recurrence, metastasis. Organoids enhance physiological relevance models, thereby improving treatment precision overcoming limitations current therapeutic approaches. Organoid technology has made preliminary applications research, including primary tumors, metastatic marrow-derived tumors. This review will explore establishment organoids, summarize their prospects various diseases, discuss integration with emerging technologies. Additionally, future directions organoid research be discussed. In future, expected to promote further development medicine.

Язык: Английский