Soil and water pollution and cardiovascular disease

Nature Reviews Cardiology, Год журнала: 2024, Номер unknown

Опубликована: Сен. 25, 2024

Язык: Английский

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Global associations between long-term exposure to PM2.5 constituents and health: A systematic review and meta-analysis of cohort studies

Journal of Hazardous Materials, Год журнала: 2024, Номер 474, С. 134715 - 134715

Опубликована: Май 23, 2024

Язык: Английский

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Association Between Short-Term Exposure to Ambient PM2.5 and Its Components with Hospital Admissions for Patients with Coronary Heart Disease and Comorbid Diabetes Mellitus in Beijing, China.

Environmental Research, Год журнала: 2025, Номер unknown, С. 120729 - 120729

Опубликована: Янв. 1, 2025

Язык: Английский

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Effect of PM2.5 and its constituents on hospital admissions for cardiometabolic multimorbidity in Urumqi, China

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 21, 2025

Cardiometabolic multimorbidity (CMM) is caused by two or more of the diseases ischemic heart disease (CVD), type 2 diabetes mellitus (T2DM), and stroke, therefore requires hospitalization healthcare costs. However, few studies have investigated fine particulate matter (PM2.5) its constituents risk hospital admissions for CMM. We aimed to study these associations in Urumqi, a representative area northwest China. The effect PM2.5 on CMM was determined using quantile-based g-computation (QBGC) bayesian kernel machine regression (BKMR) method, which with greatest were ranked as NO3− > SO42− NH4+ BC OM. Among all constituents, presented highest risk, largest observed at lag 21-day maximum concentration (RR = 2.079, 95% CI: 1.396–3.097). Per IQR increase had significantly IHD 1.079, 1.028–1.132) 1.094, 1.039–1.152). Female patients hospitalized indicated heightened sensitivity elevated levels 1.170, 1.077–1.271). interaction between high concentrations low temperature, relative humidity (RH), sunshine duration (SSD) affected Additionally, cold waves, defined minimum temperature below P2.5 sustained 5 days (CW5), intensified constituents.

Язык: Английский

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Associations between fine particulate matter and its constituents and intrahepatic cholestasis of pregnancy

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 293, С. 118010 - 118010

Опубликована: Март 1, 2025

Few studies have reported an association between intrahepatic cholestasis of pregnancy (ICP) and preconception exposure to PM2.5 sunlight duration, but there has been no in-depth analysis the correlation ICP different constituents PM2.5. Thus, we performed this retrospective among 160,544 pregnant women who delivered 2014 2020, further estimate impact PM2.5, as well duration sunlight, on via generalized linear models. During three months prior conception, adjusted odds ratios (aORs) for were 1.176 (95 % CI: 1.066, 1.298) a 10 μg/m3 increase in 1.080 1.026, 1.138) 1 sulfate (SO42-), 1.069 1.025, 1.115) organic matter (OM), 1.274 1.049, 1.546) black carbon (BC), 1.213 1.088, 1.353) 1-hour decrease duration. In addition, during period, increased (including SO42-, OM, BC) decreased interactively associated with ICP. Moreover, OM first trimester (aOR=1.043, 95 1.004, 1.083) BC both (aOR=1.201, 1.000, 1.442) second (aOR=1.278, 1.048, 1.558) found elevate risk future, preparing conceive should avoid air pollution, related anthropogenic emissions be controlled prevent these associations.

Язык: Английский

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Interaction between Extreme Temperature Events and Fine Particulate Matter on Cardiometabolic Multimorbidity: Evidence from Four National Cohort Studies

Environmental Science & Technology, Год журнала: 2024, Номер 58(28), С. 12379 - 12389

Опубликована: Июль 3, 2024

Accumulating evidence linked extreme temperature events (ETEs) and fine particulate matter (PM2.5) to cardiometabolic multimorbidity (CMM); however, it remained unknown if how ETEs PM2.5 interact trigger CMM occurrence. Merging four Chinese national cohorts with 64,140 free-CMM adults, we provided strong among ETEs, exposure, Performing Cox hazards regression models along additive interaction analyses, found that the ratio (HRs) of occurrence associated heatwave cold spell were 1.006–1.019 1.063–1.091, respectively. Each 10 μg/m3 increment concentration was 17.9% (95% confidence interval: 13.9–22.0%) increased risk CMM. Similar adverse effects also constituents nitrate, organic matter, sulfate, ammonium, black carbon. We observed a synergetic pollution on relative excess due 0.999 (0.663–1.334). Our study provides novel both exposure positively occurrence, interacts synergistically

Язык: Английский

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Loss of survivorship in nasopharyngeal carcinoma attributable to fine particulate matter and its constituents

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 293, С. 118041 - 118041

Опубликована: Март 1, 2025

Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor in East Asia, particularly impacting China. The association between multiple constituents of fine particulate matter (PM2.5) and the survival time NPC patients remains unclear, which poses challenge for targeted public health interventions. An accelerated failure-time model with 12-year cohort design was used to analyze impact long-term PM2.5 its on 1492 patients. Restricted cubic splines (RCS) functions stratification analyses were conducted identify exposure-response curve vulnerable subgroups, respectively. significantly associated reduced For per interquartile range (IQR) increase concentrations, ratio changing percentage (TRCP) ranged from -28.8 % -33.6 PM2.5, -34.7 -39.6 black carbon (BC), -13.6 -17.4 nitrate (NO3-), -21.9 -26.6 ammonium (NH4+), -29.5 -35.5 organic (OM), -31.5 -36.2 sulfate (SO42-). relationship exhibited nonlinear trend, steep slope at lower concentrations. Furthermore, females, monocyte levels, those drinking history faced higher risk time. study reveals urgent need environmental regulations mitigate constituents, BC. evidence loss survivorship crucial establishing air quality guidelines concerning PM formulating interventions protective measures high-risk

Язык: Английский

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Long-term exposure to particulate air pollution associated with the progression of type 2 diabetes mellitus in China: effect size and urban–rural disparities

BMC Public Health, Год журнала: 2025, Номер 25(1)

Опубликована: Апрель 26, 2025

Recent Western studies link long-term particulate matter (PM) exposure to type 2 diabetes mellitus (T2DM) progression, but little is known for low- and middle-income countries. This study aimed estimate the relationship between PM T2DM progression in China, also assess urban-rural disparities. Using 7-year cohort data of 1.3 million Chinese over 40, a multistate model estimated associations with progression. Covariates included demographics, socioeconomic status, health behaviors, medication, meteorological factors. Sub-sample analyses were done rural urban areas. For participants exposed high levels PM2.5 , 5-year absolute risks developing its complications 4.31% (95% CI: 4.22-4.40) 31.04% 29.97-32.08), respectively. In -exposure group, these 3.82% 3.74-3.91) 30.55% 29.43-31.65). each 10 µg/m3 increase exposure, HRs CI) from no diagnosis 1.13 (1.13-1.14), development 1.04 (1.03-1.06). Moreover, mortality risk 1.09 (1.08-1.09) without T2DM, 1.06 (1.00-1.14) those 1.10 (1.05-1.16) complications. Similar observed other PM-related metrics. areas, was more strongly associated death. Conversely, had stronger association non-T2DM state formal diagnosis. Urban residents are higher toxic components like heavy metals, potentially increasing risk, yet healthcare infrastructure offers protection against T2DM-related mortality. significantly areas should focus on primary prevention, while need improve secondary tertiary prevention services.

Язык: Английский

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Associations of insulin sensitivity and immune inflammatory responses with child blood lead (Pb) and PM2.5 exposure at an e-waste recycling area during the COVID-19 lockdown

Environmental Geochemistry and Health, Год журнала: 2024, Номер 46(8)

Опубликована: Июль 9, 2024

Язык: Английский

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Effects of PM2.5 components on hypertension and diabetes: Assessing the mitigating influence of green spaces

The Science of The Total Environment, Год журнала: 2024, Номер 959, С. 178219 - 178219

Опубликована: Дек. 23, 2024

Язык: Английский

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