Endophytic Aspergillus japonicus mediated biosynthesises of magnesium oxide nanoparticles: sustainable dye removal and in silico molecular docking evaluation of their enhanced antibacterial activity DOI Creative Commons
Reyad M. El-Sharkawy,

Mohamed Khairy,

Magdi E. A. Zaki

и другие.

Microbial Cell Factories, Год журнала: 2025, Номер 24(1)

Опубликована: Фев. 21, 2025

Sustainable biosynthesis of metal oxide nanoparticles using an eco-friendly approach is a growing research area owing to their promising environmental and biomedical applications. This work aims biosynthesize characterize magnesium (MgONPS@Aj) for possible application in dye biosorption antibacterial activity. For the first time, MgONPS@Aj was successfully synthesized by harnessing exometabolites Aspergillus japonicus. Various parameters were statistically optimized maximize production Plackett Burman's design central composite design. The analysis variance (ANOVA) revealed that pH most significant variable, affecting bioproduction process followed biomass quantity Mg2+ precursor concentration. suggested model (quadratic) greatly acceptable due nonsignificant lack fit (15.10), P-value (0.001). characterized X-ray powder diffraction, Fourier-transform infrared (FTIR) spectroscopy, transmission electron microscope (TEM), Scanning microscopy. A high capacity (204.08 mg/g) reactive black 5 achieved within 40 min mg biosorbent dose (MgONPS@Aj), 100 mg/l initial concentration, 6.0. pseudo-second-order (R2 0.9842) Langmuir isotherm 0.9422) models with dimensionless separation factor (RL) 8 × 104, hinting favorable effective molecules. 81.97 mg/g after five successive cycles hints nanomaterial suitable several time utilization. Biogenic displayed dramatic concentration-dependent activity largest inhibition zones P. aeruginosa (24.1 ± 0.8 mm, MIC: 3.125 µg/ml), E. coli (22.3 0.7 MIC 6.25), B. subtilis (14.7 0.4 12.5 µg/ml) S. aureus (19.2 0.6 6.25 µg/ml). further interpreted molecular simulation analysis. lowest binding affinity determined between target bacterial proteins (chloramphenicol acetyltransferase coli, MurE). ligand can bind active site's residues (Tyr172 SER224), indicating mechanism. study recommends as eco-friendly, reusable alternative traditional anionic sorbents uniquely candidate antimicrobial

Язык: Английский

Innovative nanocomposite comprising of ZrO2, MnCO3, and CdCO3 for superior crystal violet dye adsorption: synthesis, characterization, and regeneration insights DOI Creative Commons
Nada S. Al‐Kadhi, Ehab A. Abdelrahman, Fowzia S. Alamro

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 14, 2025

Crystal violet dye, widely used in industries, poses environmental and human health hazards due to its persistence toxicity. Effective removal methods are critical mitigate these impacts. This study presents the synthesis of a novel ZrO2@MnCO3@CdCO3 nanocomposite for efficient crystal dye from aqueous solutions. The was synthesized using precipitation method characterized XRD, SEM, EDX, BET surface area analysis. Adsorption experiments were conducted under various conditions, including pH, contact time, concentration, temperature. exhibited mesoporous structure (22.38 m2/g area, 0.0935 cm3/g total pore volume, 8.79 nm average size) an crystallite size 76.30 nm. maximum adsorption capacity 179.52 mg/g, following pseudo-second-order kinetics Langmuir isotherm. Thermodynamic studies revealed exothermic, physical, spontaneous process. Regeneration demonstrated high reusability with desorption efficiency reaching 99.67% over five cycles.

Язык: Английский

Процитировано

1
Endophytic Aspergillus japonicus mediated biosynthesises of magnesium oxide nanoparticles: sustainable dye removal and in silico molecular docking evaluation of their enhanced antibacterial activity DOI Creative Commons
Reyad M. El-Sharkawy,

Mohamed Khairy,

Magdi E. A. Zaki

и другие.

Microbial Cell Factories, Год журнала: 2025, Номер 24(1)

Опубликована: Фев. 21, 2025

Sustainable biosynthesis of metal oxide nanoparticles using an eco-friendly approach is a growing research area owing to their promising environmental and biomedical applications. This work aims biosynthesize characterize magnesium (MgONPS@Aj) for possible application in dye biosorption antibacterial activity. For the first time, MgONPS@Aj was successfully synthesized by harnessing exometabolites Aspergillus japonicus. Various parameters were statistically optimized maximize production Plackett Burman's design central composite design. The analysis variance (ANOVA) revealed that pH most significant variable, affecting bioproduction process followed biomass quantity Mg2+ precursor concentration. suggested model (quadratic) greatly acceptable due nonsignificant lack fit (15.10), P-value (0.001). characterized X-ray powder diffraction, Fourier-transform infrared (FTIR) spectroscopy, transmission electron microscope (TEM), Scanning microscopy. A high capacity (204.08 mg/g) reactive black 5 achieved within 40 min mg biosorbent dose (MgONPS@Aj), 100 mg/l initial concentration, 6.0. pseudo-second-order (R2 0.9842) Langmuir isotherm 0.9422) models with dimensionless separation factor (RL) 8 × 104, hinting favorable effective molecules. 81.97 mg/g after five successive cycles hints nanomaterial suitable several time utilization. Biogenic displayed dramatic concentration-dependent activity largest inhibition zones P. aeruginosa (24.1 ± 0.8 mm, MIC: 3.125 µg/ml), E. coli (22.3 0.7 MIC 6.25), B. subtilis (14.7 0.4 12.5 µg/ml) S. aureus (19.2 0.6 6.25 µg/ml). further interpreted molecular simulation analysis. lowest binding affinity determined between target bacterial proteins (chloramphenicol acetyltransferase coli, MurE). ligand can bind active site's residues (Tyr172 SER224), indicating mechanism. study recommends as eco-friendly, reusable alternative traditional anionic sorbents uniquely candidate antimicrobial

Язык: Английский

Процитировано

0