CLUSTER ANALYSIS IDENTIFIES LONG COVID SUBTYPES IN BELGIAN PATIENTS DOI Open Access
Pamela Mfouth Kemajou, Tatiana Besse‐Hammer,

Claire Lebouc

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2023, Номер unknown

Опубликована: Ноя. 22, 2023

Abstract SARS CoV-2 infection presents complications known as long Covid, a multisystemic organ disease which allow multidimensional analysis. Objectives This study aims to identify Long Covid clusters and relate them the clinical classification devised at Clinical Research Unit of Brugmann University Hospital, Brussels. Method A two-stage exploratory analysis was performed on cohort 205 patients, involving Factorial Analysis Mixed Data (FAMD), then Hierarchical Clustering Post Component (HCPC). Results The study’s sample comprised 76% women, with an average age 44.5 years. Three forms were identified: long, persistent, post-viral syndrome. Multidimensional identified three clusters: cluster 1 (myalgia-like pain) associated persistent form; 2 (neurocognitive disorders) linked 3 disorders, anxio-depressive syndrome, joint pain myalgia, peripheral nervous system disorders dysautonomia, including Postural Orthostatic Tachycardia Syndrome, along digestive disorders). However, biological data did not provide sufficient differentiation between clusters. Conclusion phenotypes, well forms, appear be distinct pathophysiological mechanisms or genetic predisposition, warranting further investigation.

Язык: Английский

Psychological and Social Factors Associated With Reporting Post‐COVID Symptoms Among German Healthcare Workers: A Cross‐Sectional Study DOI Creative Commons
Valentin Schick, Marietta Lieb, Andrea Borho

и другие.

Journal of Clinical Nursing, Год журнала: 2025, Номер unknown

Опубликована: Янв. 14, 2025

ABSTRACT Background Health care workers (HCW) with post‐COVID condition (PCC) are frequently reported to suffer from mental health impairment. Given HCW above‐average risk for health, research is necessary and factors need be assessed. Aim To compare of German without PCC identify associated psychological social factors. Design Cross‐sectional study. Method Overall, 2816 participated (332 PCC). Measures were symptom sum score (PCSS), symptoms depression (Patient Questionnaire‐2), anxiety (Generalised Anxiety Disorder‐2) post‐traumatic stress disorder (PTSD) (Impact Event Scale‐6), work–family conflict (Work–Family Conflict Scale), support (ENRICHD Social Support Inventory), sense coherence (Sense Of Coherence‐3 Scale) working conditions. Group differences investigated. Multiple linear regression analysis was performed PCC. PCSS the dependent variable. Independent variables a.m. measures age, gender, occupational group migration background. Results exhibited higher values, medium effect sizes, depression, PTSD. Small sizes observed conflict, support, Higher scores anxiety, PTSD levels, lower Being a physician PCSS. Conclusion Lower resources may play role in reporting severe symptoms. Further investigate these interactions using biopsychosocial theory. Implication Profession This study can help understand design adjusted treatments protect minimise their Reporting complies Journal article standards quantitative psychology: The APA Publications Communications Board task force report (Data S1). Public Contribution Caregivers sample group.

Язык: Английский

Процитировано

0

Health Resort Treatment Mitigates Neuropsychiatric Symptoms in Long COVID Patients: A Retrospective Study DOI Open Access
Grzegorz Onik, Katarzyna Knapik,

Dariusz Górka

и другие.

Healthcare, Год журнала: 2025, Номер 13(2), С. 196 - 196

Опубликована: Янв. 19, 2025

Background/Objectives: Among the neuropsychiatric symptoms of long COVID, following may be listed: sleep disturbances, headaches, anxiety, depression, dizziness, numbness, memory loss, and concentration difficulties. Various therapies have been implemented to mitigate these symptoms; however, health resort treatments that utilize a wide range modalities stimulating multidirectional biological reactions also effective. The aim this study was assess severity in COVID patients who qualified for treatment, evaluate effectiveness treatment group patients, effect balneological factors course. Methods: A retrospective analysis medical records 120 people with (69 women 51 men) aged 42–79 underwent 2021 performed. People were eligible at lowland based on valid referral from doctor. included therapies, physical medicine modalities, exercise programs, education, psychological support. Patients assessed persistent 0–10 point scale before after treatment. Results: After greatest improvement noted disorders (2.47 ± 2.23 points vs. 0.86 1.25 points, p < 0.00001) dizziness (1.39 1.94 0.34 0.76 0.00001). lowest observed (2.68 2.5 1 1.4 Conclusions: reported mild symptoms. Health mitigates symptoms, as it is complex approach. Treatment includes improves greater extent. This method should integrated into standard COVID.

Язык: Английский

Процитировано

0

Cognitive and Affective Performance of Brazilian Long COVID Patients: An In-Depth Analysis Before and After Psychoeducational Rehabilitation DOI Creative Commons

Lígia Maria do Nascimento Souza,

George P. Prigatano, Sandro Barbosa de Oliveira

и другие.

Neurorehabilitation, Год журнала: 2025, Номер unknown

Опубликована: Март 28, 2025

Background Long COVID patients report various cognitive and affective symptoms that are poorly understood. Objective This study analyzed performance in 208 pre post psychoeducational rehabilitation using a standardized screening test of higher cerebral functions. Identifying persistent difficulties may help guide future efforts. Methods The sample was comprised by subset who completed from 614 seeking rehabilitation. Performance on specific items compared to reference 114 educationally matched normal functioning adults. Results Detailed item analyses revealed the efficiency learning memory, expression, ability accurately predict verbal memory sample. showed variable deficits attention, visual-spatial problem solving measures. Language related functions were consistently at level commensurate with normally individuals. Conclusions Persistent impairments identified post-rehabilitation. Future programs should aim improve enhance range self-awareness functional capacities. Rehabilitation consider multifactorial causes these neuropsychological symptoms.

Язык: Английский

Процитировано

0

Acute serum protein biomarker profile and prevalence of persistent (>6 months) neuropsychiatric symptoms in a cohort of SARS-CoV-2 PCR positive patients in Cape Town, South Africa. DOI Creative Commons

Inette van Niekerk,

Monica Panieri,

T. Müller

и другие.

Brain Behavior & Immunity - Health, Год журнала: 2025, Номер unknown, С. 100990 - 100990

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Stress Due to Inflation: Changes over Time, Correlates, and Coping Strategies among Working-Age Adults in the United States DOI Open Access
Sophie Mitra, Chan Shen,

Jahnavi Pinnamraju

и другие.

International Journal of Environmental Research and Public Health, Год журнала: 2024, Номер 21(2), С. 157 - 157

Опубликована: Янв. 30, 2024

Background: During the COVID-19 pandemic, annual US inflation rate increased from 1.2% in July 2020 to 8% 2022. It has since declined 3.4% (December 2023). This study examined prevalence of stress due during a period when it 8.2% September 2022 3% June 2023 and its association with demographic social determinants health (SDOH). Methods: We conducted cross-sectional analysis online Household Pulse Survey (HPS), which surveils experiences households. Beginning 2022, HPS initiated data collection on “stress inflation” through question how stressful increase prices last 2 months been. Participants could respond: very, moderately, little, or not stressful. analyzed working-age adults (18–64 years) who responded above 14–26 (N = 32,579) 7–19 36,229). used replicate weights chi-squared tests ordinal logistic regression analyses controlling for gender, age, race ethnicity, COVID-19, vaccination, insurance, SDOH, including education, lost employment income, poverty status, marital food affordability, region. Results: The (price increases being very moderately stressful) significantly 76.9% 78.9% 2023. odds were higher individuals following characteristics: female, transgender, having income below 400% federal line, able afford food, had long acute did have vaccine. Conclusions: More than three quarters experienced inflation. Despite declining national recent months, among adults. Inflation-related warrants further research policy attention.

Язык: Английский

Процитировано

3

Working knowledge, uncertainty and ontological politics: An ethnography of UK long covid clinics DOI Creative Commons
Trisha Greenhalgh, Julie Darbyshire, Emma Ladds

и другие.

Sociology of Health & Illness, Год журнала: 2024, Номер 46(8), С. 1881 - 1900

Опубликована: Июль 19, 2024

Abstract Long covid (persistent COVID‐19) is a new disease with contested aetiology and variable prognosis. We report 2‐year ethnography of UK long clinics. Using preformative lens, we show that multidisciplinary teams (MDTs) built working knowledge based on shared practices, mutual trust, distributed cognition (e.g. emails, record entries), relational what was at stake for the patient, harnessing uncertainty to open discursive spaces. Most MDTs performed ‘rehabilitation’, linked set practices oriented ensuring patient understood strove ‘correct’ maladaptive physiological responses through breathing exercises) pursued recovery goals, supported by physiotherapists, psychologists generalist clinicians. Some higher proportion doctors cardiologists, neurologists, immunologists) enacted ‘microscopic damage’, seeking elucidate rectify covid’s underlying molecular cellular pathology. They justified non‐standard investigations medication in selected patients co‐constructing an evidentiary narrative biological mechanisms. Working ontologically concordant within but sometimes discordant between MDTs. Overt ontological conflict occurred mostly when attending ‘rehabilitation’ clinics invoked microscopic damage had been generated circulated online support communities.

Язык: Английский

Процитировано

3

Prescripción de ejercicio en condición pos-COVID. Un reto en Atención Primaria DOI
M.M. Yagüe Sebastián,

Sevilla Quintanilla

Medicina de Familia SEMERGEN, Год журнала: 2024, Номер 50(4), С. 102190 - 102190

Опубликована: Фев. 2, 2024

Язык: Английский

Процитировано

2

Exhaled Breath Condensate and Respiratory Sequelae in Children Post-COVID-19 DOI
Einat Fireman Klein, Karin Yaacoby‐Bianu,

Ido Orlin

и другие.

Respiration, Год журнала: 2023, Номер 102(7), С. 479 - 486

Опубликована: Янв. 1, 2023

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes an illness. A substantial proportion of adults experience persistent symptoms. There is a paucity data on sequelae in children. Exhaled breath condensate (EBC) non-invasive tool used to assess airway inflammation. Objectives: This study aimed evaluate EBC parameters, respiratory, mental and physical ability among children post COVID-19 infection. Methods: Observational confirmed SARS-CoV-2 infection cases children, aged 5–18 years, evaluated once, 1–6 months positive PCR testing. All subjects performed spirometry, 6-min walk test (6MWT), (pH, interleukin-6), completed medical history questionnaires, Depression, Anxiety, Stress Scale (DASS-21), activity scores. Severity disease was classified according WHO criteria. Results: Fifty-eight were included asymptomatic (n = 14), mild 37), moderate 7) disease. The group younger patients compared the groups (8.9 ± 2.5y vs. 12.3 3.6y 14.6 2.5y, respectively, p 0.001), as well lower DASS-21 total scores (3.4 4 8.7 9.4 0.6 0.056), with higher proximity (p 0.011). No differences found between 3 regarding EBC, 6MWT, body mass index percentile, Conclusions: asymptomatic-mild most young healthy gradually diminishing emotional Children without prolonged symptoms revealed no significant pulmonary by markers, Larger studies are required long-term pediatric consequences SARS‐CoV‐2 infection, need for pulmonology surveillance.

Язык: Английский

Процитировано

2

A pragmatic randomized controlled trial of a telemedicine self-management intervention for adults with long COVID: The COPE study protocol DOI Creative Commons
Lindsey M. Knowles,

Mehr Grewal,

Sydney Drever

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Фев. 26, 2024

Abstract Background : Long COVID is a serious public health concern due to its high prevalence and potentially debilitating symptoms. Symptoms may include fatigue, dyspnea, cognitive problems, insomnia, anxiety depression. There currently no cure for long the average length of recovery proportion patients who fully recover are still unknown. Subsequently, there critical need improve function. Research in other chronic conditions suggests that psychosocial self-management interventions reduce symptom severity interference with functioning. We describe design our study examine feasibility, acceptability, appropriateness preliminary efficacy an intervention designed management coping adults COVID. Methods This pilot trial ( N =50) uses pragmatic, randomized 2-group parallel set within MASKED Post-COVID Rehabilitation Recovery Clinic. The 6-week, group-based telemedicine teaches evidence-based strategies manage common symptoms stress as well communication self-advocacy. comparator wait-list control. Participants complete self-report measures primary secondary outcomes at baseline post-treatment/wait-list. Primary appropriateness. Secondary Patient-Reported Outcomes Measurement Information System sleep disturbance, difficulties, self-efficacy, pain interference, depression measure impression change. At post-intervention, participants also qualitative interview inform refinement. Quantitative data will be examined using descriptive statistical analysis including t tests chi-square compare groups on outcomes. Qualitative analyzed rigorous accelerated reduction technique. Discussion Results this controlled characterize refinement necessary prior further testing. rehabilitation approaches equip patient function quality life burden system. Clinical Trial Registration No. NCT05658536. Date December 16, 2022

Язык: Английский

Процитировано

0

Long/Post-COVID-Syndrom DOI Creative Commons

Carolin Thurner,

Andreas Stengel

Zeitschrift für Psychodrama und Soziometrie, Год журнала: 2024, Номер 23(2), С. 357 - 364

Опубликована: Май 3, 2024

Zusammenfassung In diesem Artikel der Zeitschrift für Psychodrama und Soziometrie wird die Behandlung von Patient*innen mit Long/Post-COVID-Syndrom diskutiert. Dabei ist das Krankheitsbild geprägt multiplen, diffusen aktuellen Diagnosemethoden meist somatisch nicht erklärbaren Symptomen. schlagen wir Einordnung als Somatic Symptom Disorder eine interdisziplinäre auf Basis des biopsychosozialen Modells vor.

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