A Novel Tri-Coordination Zinc Complex Functionalized Silicotungstate with ROS Catalytic Ability and Anti-Tumor Cells Activity DOI Open Access
Xiang Ma, Jiai Hua, Man Wang

и другие.

Catalysts, Год журнала: 2022, Номер 12(7), С. 695 - 695

Опубликована: Июнь 24, 2022

Reactive oxygen species (ROS) can be used as an effective method to treat tumors. Artificial oxidase has received increasing attention a catalyst for ROS generation in fields ranging from bioinorganic chemistry pharmaceutical chemistry. In this study, artificial based on binuclear zinc complex and Keggin-type silicotungstate [Zn2(4,4′-bpy)(Phen)2][SiW12O40] (ZSW) (4,4′-bpy = 4,4′-bipyridine; Phen 1,10-phenanthroline) was synthesized structurally featured terms of its X-ray photoelectron spectrum (XPS), bond valence sum (Σs) calculation, IR spectra, single-crystal diffraction (SXRD). ZSW is ionic compound which the cation [Zn2(4,4′-bpy)(Phen)2]4+ anion α-Keggin-type [SiW12O40]4– cluster. Notably, Zn ions [Zn2(4,4′-bpy)(Phen)2] exist tri-coordination, first obtained polyoxometalate (POM) It also demonstrated that capable efficiently catalyzing production ROS, which, according computational calculations, may due synergistic action complexes POM building blocks. Furthermore, exhibited inhibition ability toward ROS-sensitive tumor cells, such PC12 cells.

Язык: Английский

Recent advances in the development of polyoxometalates and their composites for the degradation of toxic chemical dyes DOI

Gajiram Murmu,

Tamanna Harihar Panigrahi,

Sumit Saha

и другие.

Progress in Solid State Chemistry, Год журнала: 2024, Номер unknown, С. 100489 - 100489

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

3

A Nanoenzyme Constructed from Manganese and Strandberg-Type Phosphomolybdate with Versatility in Antioxidant and Modulating Conformation of Aβ Protein Misfolding Aggregates In Vitro DOI Open Access
Jiai Hua, Feng Wang,

Xueman Wei

и другие.

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(5), С. 4317 - 4317

Опубликована: Фев. 21, 2023

Amyloid β-peptide (Aβ) misfolding aggregates with β-sheet structures and surplus reactive oxygen species (ROS) are both considered to be the culprit of neuronal toxicity in Alzheimer's disease (AD). Therefore, modulating mode Aβ inhibiting ROS simultaneous has become an important method for anti-AD. Herein, a nanoscale manganese-substituted polyphosphomolybdate (H2en)3[Mn(H2O)4][Mn(H2O)3]2[P2Mo5O23]2·14.5H2O (abbreviated as MnPM) (en = ethanediamine) was designed synthesized by single crystal transformation method. MnPM can modulate rich conformation aggregates, thus reduce formation toxic species. Moreover, also possesses ability eliminate free radicals produced Cu2+-Aβ aggregates. It inhibit cytotoxicity β-sheet-rich protect synapses PC12 cells. combines anti-oxidation ability, which makes promising multi-funcational molecular composite mechanism new conceptual designing treatment such protein-misfolding diseases.

Язык: Английский

Процитировано

6

A Cyclen-Functionalized Cobalt-Substituted Sandwich-Type Tungstoarsenate with Versatility in Removal of Methylene Blue and Anti-ROS-Sensitive Tumor Cells DOI Creative Commons
Jiai Hua,

Xueman Wei,

Yifeng Li

и другие.

Molecules, Год журнала: 2022, Номер 27(19), С. 6451 - 6451

Опубликована: Сен. 30, 2022

Oxidative degradation by using reactive oxygen species (ROS) is an effective method to treat pollutants. The synthesis of artificial oxidase for the dyes a hot spot in molecular science. In this study, nanoscale sandwich-type polyoxometalate (POM) on basis tetra-nuclear cobalt cluster and trivacant B-α-Keggin-type tungstoarsenate {[Co(C8H20N4)]4}{Co4(H2O)2[HAsW9O34]2}∙4H2O (abbreviated as CAW, C8H20N4 = cyclen) has been synthesized structurally examined infrared (IR) spectrum, ultraviolet-visible (UV-Vis) X-ray photoelectron spectrum (XPS), single-crystal diffraction (SXRD), bond valence sum (Σs) calculation. According structural analysis, principal element CAW derived from modifying polyanion {Co4(H2O)2 [HAsW9O34]2}8- with four [Co(Cyclen)]2+, which 1,4,7,10-tetraazacyclododecane (cyclen) firstly applied modify POM. It also demonstrated that capable efficiently catalyzing production ROS synergistic effects POM fragments Co-cyclen complexes. Moreover, can interfere morphology proliferation sensitive cells producing exhibits ability specifically eliminating methylene blue (MB) solution system both adsorption catalytic oxidation.

Язык: Английский

Процитировано

7

An 1,4,7,10-tetraazacyclododecane-nickel complex functionalized polymolybdate acting as artificial oxidase in removing methylene blue DOI
Xiang Ma,

Yujin Li,

Longfeng Meng

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1312, С. 138502 - 138502

Опубликована: Май 3, 2024

Язык: Английский

Процитировано

1

Nano Ag/AgCl wires-photocatalyzed hydrogen production and transfer hydrogenation of Knoevenagel-type products DOI
Yasser A. Attia, Yasser M. A. Mohamed

New Journal of Chemistry, Год журнала: 2021, Номер 46(4), С. 1677 - 1686

Опубликована: Дек. 13, 2021

An investigation of the relationship between morphology Ag/AgCl nanostructured composites with their catalytic performance has been reported.

Язык: Английский

Процитировано

8

A hexa-Cu cluster sandwiched silicotungstate with reactive oxygen species catalytic ability and anti-tumor activity in PC12 cells DOI
Xiang Ma,

Xueman Wei,

Man Wang

и другие.

Journal of Molecular Structure, Год журнала: 2022, Номер 1267, С. 133616 - 133616

Опубликована: Июнь 30, 2022

Язык: Английский

Процитировано

6

A Novel Tri-Coordination Zinc Complex Functionalized Silicotungstate with ROS Catalytic Ability and Anti-Tumor Cells Activity DOI Open Access
Xiang Ma, Jiai Hua, Man Wang

и другие.

Catalysts, Год журнала: 2022, Номер 12(7), С. 695 - 695

Опубликована: Июнь 24, 2022

Reactive oxygen species (ROS) can be used as an effective method to treat tumors. Artificial oxidase has received increasing attention a catalyst for ROS generation in fields ranging from bioinorganic chemistry pharmaceutical chemistry. In this study, artificial based on binuclear zinc complex and Keggin-type silicotungstate [Zn2(4,4′-bpy)(Phen)2][SiW12O40] (ZSW) (4,4′-bpy = 4,4′-bipyridine; Phen 1,10-phenanthroline) was synthesized structurally featured terms of its X-ray photoelectron spectrum (XPS), bond valence sum (Σs) calculation, IR spectra, single-crystal diffraction (SXRD). ZSW is ionic compound which the cation [Zn2(4,4′-bpy)(Phen)2]4+ anion α-Keggin-type [SiW12O40]4– cluster. Notably, Zn ions [Zn2(4,4′-bpy)(Phen)2] exist tri-coordination, first obtained polyoxometalate (POM) It also demonstrated that capable efficiently catalyzing production ROS, which, according computational calculations, may due synergistic action complexes POM building blocks. Furthermore, exhibited inhibition ability toward ROS-sensitive tumor cells, such PC12 cells.

Язык: Английский

Процитировано

5