Advancing health equity in the aftermath of COVID-19: Confronting intensifying racial disparities

iScience, Год журнала: 2024, Номер 27(7), С. 110257 - 110257

Опубликована: Июнь 13, 2024

The COVID-19 pandemic has exposed and exacerbated the persistent racial ethnic health disparities in United States. also had profound spillover effects on other aspects of wellbeing, such as mental health, chronic diseases, education, income, for marginalized groups. In this article, we provide a thorough analysis pandemic's impact disproportionalities, highlighting multifaceted interrelated factors that contribute to these inequities. We argue renewed focus equity healthcare policy practice, emphasizing need systemic changes address both immediate long-term consequences imbalances. propose framework achieving involves creating equitable systems, care, outcomes all individuals, regardless their race or ethnicity.

Язык: Английский

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A dynamical model of drinking and smoking with optimal control analysis

PLoS ONE, Год журнала: 2024, Номер 19(12), С. e0311835 - e0311835

Опубликована: Дек. 19, 2024

The intake of alcohol is dangerous, and the smoking tobacco savage, but it life-threatening to practice both drinking. According World Health Organisation, world loses about 8.5 million people each year as a result drinking alcohol. To study this, we present mathematical model that investigates co-dynamics smoking, well some control strategies. In contrast, many studies focus solely on dynamics consumption or smoking. Also, these assume an individual who may recover from relapse. We determined basic reproductive number by employing next-generation matrix approach. conducted local global stability analyses for drinking, smoking-free, endemic states. then extensive research into secondary infections related performed numerical simulations analysis using parameter values literature. further examined influence key parameters co-dependence infections, which occur when one infected enters population recovers over time. For example, in this study, was shown contact rates 1 2 have direct relationship spread recovery δ , showed inverse relationship. addition, optimal suggesting following: prevention efforts, efforts indicated controls can help reduce smokers drinkers within eight weeks.

Язык: Английский

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Unraveling COVID-19 relationship with anxiety disorders and symptoms using genome-wide data

Journal of Affective Disorders, Год журнала: 2024, Номер 352, С. 333 - 341

Опубликована: Фев. 19, 2024

Язык: Английский

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Влияние внешних шоков на нездоровое поведение: пандемия COVID-19 и потребление алкоголя

Monitoring obŝestvennogo mneniâ: èkonomičeskie i socialʹnye peremeny, Год журнала: 2024, Номер 1

Опубликована: Март 4, 2024

Статья посвящена исследованию влияния внешних шоков, связанных с пандемией COVID-19, на вероятность и объемы потребления алкоголя в России. Переменными интереса выступают показатели избыточной смертности регионе проживания человека (переменная, отвечающая за стресс) безработицы (переменная экономического неблагополучия). Комбинируя микроданные РМЭЗ НИУ ВШЭ региональные данные Росстата, авторы оценивают эконометрические модели 2019-2021 гг. отдельно для мужчин женщин. Проведенный анализ показал, что ростом уровня 1% снижалась 2% у женщин 3% 2020 г., 2021 г. В чистого этанола среди пьющих респондентов увеличивались 1-2% единицу (то есть 1 расчете 100 тыс. жителей) — это верно мужчин, Однозначной связи объемов потребляемого безработицей при этом не выявлено. Исследование подтверждает гипотезу о том, изменения потреблении российским населением 2020-2021 были обусловлены разнонаправленными факторами стрессом ухудшением положения. Некоторые другие факторы поменяли свою значимость сравнении «доковидным» годом: стало влиять образование, причем положительно, а отрицательно. базовым уровнем женщин, имеющих образование более высоких ступеней, потреблять алкоголь хотя бы иногда возрастает 20-30%, напротив, снижается 10%. отличие от предыдущих лет, вероятность, доходом как так Одновременно снижались жителями поселков, наоборот стали больше пить мужчины, живущие столицах. подтверждает, потребление находится под влиянием целого ряда факторов микро-, макроуровня, пандемия COVID-19 оказала воздействие общую динамику алкоголя. Благодарность. проводилось рамках проекта Программы фундаментальных исследований ВШЭ.

Язык: Русский

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Consumption of ultra-processed foods and mental health of pregnant women from the South of Brazil

British Journal Of Nutrition, Год журнала: 2024, Номер 132(1), С. 107 - 114

Опубликована: Апрель 22, 2024

Abstract The objective of this study is to evaluate the association between consumption ultra-processed foods (UPF) and mental health pregnant women from South Brazil. This a cross-sectional carried out in Criciúma, Brazil, through face-to-face interviews, April December 2022. Pregnant aged 18 or older who underwent prenatal care forty-eight basic units municipality were their third trimester pregnancy included. High UPF was considered as six more items subgroups consumed on day before interview, using Nova-UPF screener. variables depressive symptoms, stress, sadness anxiety. Crude adjusted analyses conducted Fisher’s exact test Poisson regression with robust variance. In total, 428 studied; most them 20 25 years white. presented high 1·42-fold (95 % CI 1·06, 1·92) likely experience anxiety prevalence 56 1·18, 2·07) higher stress when compared those did not present UPF. symptoms feelings 1·31-fold 1·08, 1·60) 3·41-fold 1·77, 6·58) among UPF, respectively. results suggest that diet quality associated women. Promoting joint actions focused food nutritional education, health, for women, necessary.

Язык: Английский

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Mental health status and quality of life among Thai people after the COVID-19 outbreak: a cross-sectional study

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Окт. 29, 2024

The coronavirus disease 2019 (COVID-19) pandemic has had a profound impact on individuals' mental health and well-being worldwide. This study investigated the prevalences of association between quality life (QOL) in Thailand after COVID-19 outbreak. A cross-sectional was conducted among Thai individuals aged ≥ 20 years across all regions. Descriptive statistics, chi-square tests, multiple logistic regression analyses were performed to examine QOL. total 1,133 participants (mean age: 35.1 ± 17.2 years) completed survey. prevalence depression with PHQ-9 instrument 19.4%. Depression significantly associated those who have family members die from infection (adjusted odds ratio [AOR] 2.27, 95% confidence interval [CI] [1.13-4.52]). percentages depression, anxiety, stress DASS-21 32.4%, 45.4%, 24.1%, respectively. Smokers alcohol consumption approximately 1.5-time higher risk compared non-smokers no (AOR = 1.50, CI [1.01-2.24], AOR 1.48, [1.09-2.02], respectively). An observed socioeconomic factors such as job income loss outcomes. Depression, negatively demonstrates strong QOL people findings underscore need for interventions targeting lifestyles, including addressing smoking, especially support services that can address improve overall population.

Язык: Английский

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Integrative multi-omics analysis to gain new insights into COVID-19

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Ноя. 30, 2024

Abstract Multidimensional host and viral factors determine the clinical course of COVID-19. While virology disease is well studied, investigating host-related factors, including genome, transcriptome, metabolome, exposome, can provide valuable insights into underlying pathophysiology. We conducted integrative omics analyses to explore their intricate interplay in used data from UK Biobank (UKB), employed single-omics, pairwise-omics, multi-omics models illustrate effects different layers. The dataset included COVID-19 phenotypic as imputed-transcriptome, metabolome exposome data. examined main, interaction correlations between layers Single-omics showed that transcriptome (derived coronary artery tissue) captured 3–4% variation susceptibility, while genome contributed 2–2.5% variation. In omics-exposome model, where individual were simultaneously fitted with data, contributions diminished considered negligible, whereas minimal change. Through mediation analysis, findings revealed exposomic mediated about 60% metabolome’s effects, having a relatively minor impact on mediating only 7% its effects. conclusion, our integrative-omics shed light contribution variance

Язык: Английский

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Male Clinical Parameters (Age, Stature, Weight, Body Mass Index, Smoking History, Alcohol Consumption) Bear Minimal Relationship to the Level of Sperm DNA Fragmentation

Journal of Personalized Medicine, Год журнала: 2023, Номер 13(5), С. 759 - 759

Опубликована: Апрель 28, 2023

This retrospective cohort study reports on 1291 males who were the partners of women presenting with infertility requiring assisted reproduction and had sperm DNA fragmentation (SDF) levels measured by Halosperm test. These men provided clinical biometric details which included their age, stature, weight, body mass index (BMI). Of these men, 562 (43.5%) detailed historical records smoking alcohol histories. The aim this was to determine whether any parameters, or main lifestyle factors, influence SDF. We found that only parameter a direct correlation advancing age (r = 0.064, p 0.02), but none parameters BMI showed significant correlation. In respect lifestyle, there correlations history, not in way we expected. Our data significantly elevated SDF among non-smokers (p 0.03) compared smokers. also that, non-smokers, ex-smokers higher 0.03). With alcohol, consumers did show differences levels. findings relevance an level <15% ≥15%. Furthermore, logistic regression analysis excluded as confounder findings. It is therefore concluded apart from both aspects have minimal

Язык: Английский

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Household food insecurity before and during COVID-19 pandemic and its association with perceived stress: population-based studies

Cadernos de Saúde Pública, Год журнала: 2023, Номер 39(1)

Опубликована: Янв. 1, 2023

The growing prevalence of food insecurity observed in the last years, has been favored by COVID-19 pandemic, leading to mental health issues, such as stress. We aim analyze household before and during pandemic its association with perceived analyzed data from two population-based studies conducted 2019 2020-2021 municipality Criciúma, State Santa Catarina, Southern Brazil. Food stress were assessed Brazilian Insecurity Scale Perceived Stress Scale. covariables sex, age, skin color, schooling level, income, job status, marital crowding, overweight, diet quality. Crude adjusted associations between using Poisson regression. A total 1,683 adult individuals assessed. Prevalence was 25.8% 2019, decreasing 21.6% 2020. about 38% for both years. Before increased 29% (PR = 1.29; 95%CI: 1.02; 1.63), but no found COVID-19. a worrying after de nonetheless associated only 2019. An assessment these aspects is needed ensure basic life rights all.

Язык: Английский

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Mental Health Conditions– and Substance Use—Associated Emergency Department Visits during the COVID-19 Pandemic in Nevada, USA

International Journal of Environmental Research and Public Health, Год журнала: 2023, Номер 20(5), С. 4389 - 4389

Опубликована: Март 1, 2023

Background—Mental health conditions and substance use are linked. During the COVID-19 pandemic, mental increased, while emergency department (ED) visits decreased in U.S. There is limited information regarding how pandemic has affected ED for patients with use. Objectives—This study examined changes associated more common serious (suicidal ideation, suicide attempts, schizophrenia) commonly used substances (opioids, cannabis, alcohol, cigarettes) Nevada during 2020 2021 compared pre-pandemic period. Methods—The State database from 2018 to was (n = 4,185,416 visits). The 10th Revision of International Classification Diseases identified suicidal schizophrenia, opioids, cigarette smoking. Seven multivariable logistic regression models were developed each after adjusting age, gender, race/ethnicity, payer source. reference year set as 2018. Results—During both years (2020 2021), particularly 2020, odds smoking, alcohol all significantly higher than those Conclusions—Our findings indicate impact on health- use-associated provide empirical evidence policymakers direct develop decisive public initiatives aimed at addressing service utilization, especially early stages large-scale emergencies, such pandemic.

Язык: Английский

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