Brain Research, Год журнала: 2024, Номер unknown, С. 149348 - 149348
Опубликована: Ноя. 1, 2024
Язык: Английский
Journal of Obesity & Metabolic Syndrome, Год журнала: 2024, Номер 33(2), С. 92 - 107
Опубликована: Май 13, 2024
Intermittent fasting (IF), a dietary pattern alternating between eating and periods within 24-hour cycle, has garnered recognition for its potential to enhance both healthspan lifespan in animal models humans. It also shows promise alleviating age-related diseases, including neurodegeneration. Vascular cognitive impairment (VCI) spans severity range from mild deficits severe loss of function vascular dementia. Chronic cerebral hypoperfusion emerged as significant contributor VCI, instigating pathologies such microbleeds, blood-brain barrier dysfunction, neuronal loss, white matter lesions. Preclinical studies rodents strongly suggest that IF the attenuate pathological mechanisms, excitotoxicity, oxidative stress, inflammation, cell death pathways VCI models. Hence, this supports evaluating clinical trials existing at-risk patients. This review compiles data supporting IF's treating VCI-related pathologies, emphasizing mechanisms by which may mitigate these issues. Hence providing comprehensive overview available underlying make promising intervention VCI.
Язык: Английский
Процитировано
4
Frontiers in Nutrition, Год журнала: 2025, Номер 12
Опубликована: Март 19, 2025
The metabolites of the ketogenic diet (KD), specifically ketone bodies (KB), are closely linked to brain health. KD is widely used treat epilepsy. It's also getting more attention for treating neurodegenerative disorders like Alzheimer's and Parkinson's diseases, its effectiveness in these areas well - recognized. This study aims explore research hotspots field health from 2013 2024, providing references directions future research. utilized R software, VOSviewer, CiteSpace analyze 1,162 publications this 2024. A total were included study. From 2021, there was an upward trend number field, followed by a slight decline 2021 2023. United States has highest exhibits most extensive collaboration with other countries, positioning it as leading nation field. journal Nutrients publications, while Epilepsia cited journal. Key subject terms include KD, Brain, Beta-Hydroxybutyrate, KB, Metabolism, Oxidative Stress. primary focuses application such epilepsy, role mechanisms metabolism, effects physiological properties (e.g., KB) antioxidative stress neuroprotection on beneficial health, use garnered widespread recognition globally. provides comprehensive in-depth analysis literature offering valuable insights into investigation.
Язык: Английский
Процитировано
0
CNS Neuroscience & Therapeutics, Год журнала: 2024, Номер 30(9)
Опубликована: Сен. 1, 2024
Extended fasting-postprandial switch intermitting time has been shown to affect Alzheimer's disease (AD). Few studies have investigated the cerebral perfusion response metabolic switching (FMS) in AD patients. We aimed evaluate FMS
Язык: Английский
Процитировано
2
npj Metabolic Health and Disease, Год журнала: 2024, Номер 2(1)
Опубликована: Дек. 30, 2024
Intermittent fasting focuses on the timing of eating rather than diet quality or energy intake, with evidence supporting its effects weight loss and improvements in cardiometabolic outcomes adults obesity. However, there is limited for feasibility efficacy young people. To address this, a scoping review was conducted to examine intermittent regimens individuals aged 10 25 treatment obesity focusing methodology, intervention parameters, outcomes, adherence, feasibility, efficacy. Due paucity this age group, adequately assess all published studies category, regardless status intention, were included review. The 34 (28 interventional 6 observational studies) 893 participants 12 25. Interventions varied 9 cohorts utilizing as an treatment. Thirteen utilized 8-h time-restricted eating. Primary risk factors (7/28), anthropometric measurements body composition (5/28), muscular performance (4/28), (1/28), others (4/28). All people reported some degree loss, although comparator groups significantly. This underscores various utilizations group highlights potential treating findings emphasize need rigorous standardized frameworks ensure comparability determine fasting's practicality depending outcome interest.
Язык: Английский
Процитировано
2
Experimental Neurology, Год журнала: 2024, Номер 381, С. 114920 - 114920
Опубликована: Авг. 12, 2024
Язык: Английский
Процитировано
1
Research Square (Research Square), Год журнала: 2024, Номер unknown
Опубликована: Июль 1, 2024
Intermittent fasting (IF) focuses on the timing of eating rather than diet quality or energy intake, with evidence supporting its effects weight loss and cardiometabolic outcomes in adults. However, there is limited for efficacy adolescents emerging To address this, a scoping review examined IF regimens individuals aged 10 to 25, focusing methodology, intervention parameters, outcomes, adherence, feasibility, efficacy. The included 39 studies 731 participants 15 25. Methodologies varied, 18 time-restricted others requiring caloric restriction. Primary risk factors (11/29), body composition (9/29), anthropometric measurements (8/29), feasibility (2/29). Most reported significant loss. This underscores IF's potential treating obesity this age group but highlights need rigorous standardized frameworks ensure comparability determine practicality group.
Язык: Английский
Процитировано
0
Brain Research, Год журнала: 2024, Номер unknown, С. 149348 - 149348
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
0