Heliyon,
Год журнала:
2024,
Номер
10(22), С. e40233 - e40233
Опубликована: Ноя. 1, 2024
Premenstrual
syndrome
(PMS)
encompasses
a
range
of
emotional,
physiological,
and
behavioral
symptoms
that
occur
during
the
luteal
phase
menstrual
cycle
(MC)
resolve
with
onset
menstruation.
These
symptoms,
which
can
include
fatigue,
physical
pain,
anxiety,
irritability,
depression,
significantly
affect
women's
daily
lives
overall
well-being.
In
severe
cases,
PMS
progress
to
premenstrual
dysphoric
disorder
(PMDD),
profoundly
impairing
quality
life.
Despite
its
prevalence,
neural
mechanisms
underlying
PMS-particularly
those
related
stress-are
not
fully
understood.This
review
aims
explore
complex
interactions
between
stress,
focus
on
hormonal
pathways
involved.
We
propose
abnormal
stress
coping
styles
reactivity
patterns,
collectively
referred
as
dysfunction,
are
crucial
factors
influencing
vulnerability
PMS.
examine
relationship
from
four
perspectives:
(1)
shares
neuroendocrine
metabolic
circuits
based
fluctuations
systems;
(2)
there
is
comorbidity
stress-related
disorders;
(3)
itself
may
act
stressor,
potentially
creating
negative
feedback
loop
exacerbates
symptoms;
(4)
biofeedback
training
used
for
disorders
be
effective
in
treating
By
providing
detailed
analysis
changes
their
effects
PMS,
this
offers
new
insights
into
physiological
processes
Understanding
these
inform
development
targeted
interventions
improve
life
women
affected
by
Caderno Pedagógico,
Год журнала:
2024,
Номер
21(9), С. e7373 - e7373
Опубликована: Сен. 3, 2024
A
dermatite
atópica
é
uma
condição
crônica
multifatorial,
frequentemente
associada
a
outras
comorbidades,
como
asma,
rinite
alérgica
e
disfunções
da
barreira
cutânea.
O
tratamento
eficaz
continua
sendo
um
desafio
significativo,
exigindo
novas
abordagens
terapêuticas.
Este
estudo
visa
revisar
as
evidências
científicas
sobre
terapêuticas
inovadoras
no
moderada
grave.
Utilizou-se
revisão
narrativa
literatura,
abrangendo
estudos
clínicos,
meta-análises
revisões
sistemáticas
publicados
em
bases
de
dados
científicas.
Os
resultados
indicam
que
terapias
demonstram
eficácia
notável
na
redução
dos
sintomas
melhora
qualidade
vida
pacientes.
mecanismos
ação
dessas
incluem
modulação
resposta
inflamatória
restauração
função
Ensaios
clínicos
essas
intervenções
proporcionam
alívio
significativo
sustentado
sintomas,
comparável
ou
superior
outros
tratamentos
disponíveis.
Além
disso,
o
perfil
segurança
considerado
aceitável,
com
efeitos
adversos
geralmente
manejáveis.
conclui
representam
novo
paradigma
atópica,
oferecendo
alternativas
eficazes
para
pacientes
não
respondem
adequadamente
convencionais.
No
entanto,
destaca-se
necessidade
longo
prazo
manutenção
uso
prolongado.
reforça
importância
personalizadas,
sugerindo
podem
transformar
significativamente
estratégias
manejo
melhorar
Heliyon,
Год журнала:
2024,
Номер
10(22), С. e40233 - e40233
Опубликована: Ноя. 1, 2024
Premenstrual
syndrome
(PMS)
encompasses
a
range
of
emotional,
physiological,
and
behavioral
symptoms
that
occur
during
the
luteal
phase
menstrual
cycle
(MC)
resolve
with
onset
menstruation.
These
symptoms,
which
can
include
fatigue,
physical
pain,
anxiety,
irritability,
depression,
significantly
affect
women's
daily
lives
overall
well-being.
In
severe
cases,
PMS
progress
to
premenstrual
dysphoric
disorder
(PMDD),
profoundly
impairing
quality
life.
Despite
its
prevalence,
neural
mechanisms
underlying
PMS-particularly
those
related
stress-are
not
fully
understood.This
review
aims
explore
complex
interactions
between
stress,
focus
on
hormonal
pathways
involved.
We
propose
abnormal
stress
coping
styles
reactivity
patterns,
collectively
referred
as
dysfunction,
are
crucial
factors
influencing
vulnerability
PMS.
examine
relationship
from
four
perspectives:
(1)
shares
neuroendocrine
metabolic
circuits
based
fluctuations
systems;
(2)
there
is
comorbidity
stress-related
disorders;
(3)
itself
may
act
stressor,
potentially
creating
negative
feedback
loop
exacerbates
symptoms;
(4)
biofeedback
training
used
for
disorders
be
effective
in
treating
By
providing
detailed
analysis
changes
their
effects
PMS,
this
offers
new
insights
into
physiological
processes
Understanding
these
inform
development
targeted
interventions
improve
life
women
affected
by
