Marine diseases and the Anthropocene: Understanding microbial pathogenesis in a rapidly changing world DOI Creative Commons
Jennifer Hudson, Suhelen Egan

Microbial Biotechnology, Год журнала: 2024, Номер 17(1)

Опубликована: Янв. 1, 2024

Abstract Healthy marine ecosystems are paramount for Earth's biodiversity and key to sustaining the global economy human health. The effects of anthropogenic activity represent a pervasive threat productivity ecosystems, with intensifying environmental stressors such as climate change pollution driving occurrence severity microbial diseases that can devastate jeopardise food security. Despite potentially catastrophic outcomes diseases, our understanding host‐pathogen interactions remains an understudied aspect both microbiology research, especially when compared depth information available agricultural systems. Here, we identify three avenues research in which advance disease context change, make positive steps towards safeguarding communities future generations.

Язык: Английский

Differentiation and Maturation of Muscle and Fat Cells in Cultivated Seafood: Lessons from Developmental Biology DOI Creative Commons
Claire Bomkamp, Lisa Musgrove, Diana M. C. Marques

и другие.

Marine Biotechnology, Год журнала: 2022, Номер 25(1), С. 1 - 29

Опубликована: Ноя. 14, 2022

Abstract Cultivated meat, also known as cultured or cell-based is meat produced directly from animal cells rather than a whole animal. and seafood have been proposed means of mitigating the substantial harms associated with current production methods, including damage to environment, antibiotic resistance, food security challenges, poor welfare, and—in case seafood—overfishing ecological fishing aquaculture. Because biomedical tissue engineering research, which cultivated draws great deal inspiration, has thus far conducted almost exclusively in mammals, suffers lack established protocols for producing complex tissues vitro. At same time, fish such zebrafish Danio rerio widely used model organisms developmental biology. Therefore, many mechanisms signaling pathways involved formation muscle, fat, other relevant are relatively well understood this species. The processes lesser degree aquatic invertebrates. This review discusses differentiation maturation meat-relevant cell types species makes recommendations future research aimed at recapitulating these produce shellfish.

Язык: Английский

Процитировано

39

Assigning cause for emerging diseases of aquatic organisms DOI
Kate S. Hutson, Ian Davidson, Jerusha Bennett

и другие.

Trends in Microbiology, Год журнала: 2023, Номер 31(7), С. 681 - 691

Опубликована: Фев. 23, 2023

Язык: Английский

Процитировано

18

The evolution of aging and lifespan DOI Creative Commons

Stacy Li,

Juan Manuel Vázquez, Peter H. Sudmant

и другие.

Trends in Genetics, Год журнала: 2023, Номер 39(11), С. 830 - 843

Опубликована: Сен. 14, 2023

Aging is a nearly inescapable trait among organisms yet lifespan varies tremendously across different species and spans several orders of magnitude in vertebrates alone. This vast phenotypic diversity driven by distinct evolutionary trajectories tradeoffs that are reflected patterns diversification constraint organismal genomes. Age-specific impacts selection also shape allele frequencies populations, thus impacting disease susceptibility environment-specific mortality risk. Further, the mutational processes spawn this genetic both germline somatic cells strongly influenced age life history. We discuss recent advances our understanding evolution aging at organismal, population, cellular scales, highlight outstanding questions remain unanswered.

Язык: Английский

Процитировано

17

Distinguishing between ante factum and post factum properties of animal cell lines and demonstrating their use in grouping ray-finned fish cell lines into invitromes DOI
Niels C. Bols, Lucy E. J. Lee, Georgina C. Dowd

и другие.

In Vitro Cellular & Developmental Biology - Animal, Год журнала: 2023, Номер 59(1), С. 41 - 62

Опубликована: Янв. 1, 2023

Язык: Английский

Процитировано

15

Detrimental effects of individual versus combined exposure to tetrabromobisphenol A and polystyrene nanoplastics in fish cell lines DOI Creative Commons
Patricia Soto‐Bielicka, Inés Tejeda, Ana Peropadre

и другие.

Environmental Toxicology and Pharmacology, Год журнала: 2023, Номер 98, С. 104072 - 104072

Опубликована: Янв. 20, 2023

The potential interactions between the diverse pollutants that can be released into environment and resulting outcomes are a challenging issue needs to further examined. This in vitro study was aimed assess toxic effects caused by combined exposure tetrabromobisphenol A, flame retardant widely used frequently detected aquatic matrices, commercially available polystyrene nanoparticles as reference material evaluate nanoplastics risks. Our results, using freshwater fish cell lines set of relevant cytotoxicity endpoints including viability, oxidative stress, DNA damage, provide additional mechanistic insights could help fully characterize toxicity profiles A nanoparticles. Furthermore, we describe subtle changes viability well generation damage after coexposure subcytotoxic concentrations tested pollutants.

Язык: Английский

Процитировано

14

The use of fish cell lines as in-vitro ecotoxicological tools: A cellular solution to aquaculture sustainability DOI Creative Commons
Thao V. Nguyen, Anupama Kumar, Phan Nguyen Trang

и другие.

Aquaculture, Год журнала: 2024, Номер 593, С. 741302 - 741302

Опубликована: Июнь 28, 2024

Aquaculture plays a crucial role in meeting the growing demand for seafood worldwide. However, sustainability of aquaculture practices faces challenges from environmental pollutants and toxins. Traditional methods assessing aquatic toxicity often rely on whole organism tests, which can be time-consuming, expensive, ethically challenging. In recent years, utilization fish cell lines as in-vitro testing models toxicology has emerged promising alternative approach. Fish offer several advantages, including cost-effectiveness, scalability, reduced ethical concerns. This review paper provides an overview implementation toxicology, focusing their applications contaminants, mechanistic studies, biomarker discovery. Furthermore, we discuss advantages limitations compared to traditional tests explore future perspectives integrating into regulatory frameworks. Overall, integration holds great promise enhancing safety face increasing pressures.

Язык: Английский

Процитировано

5

Genomic and cellular contributions to establish the fish Hyphessobrycon heterorhabdus as an Amazonian model for ecotoxicology DOI Creative Commons
Adauto Lima Cardoso, Camila do Nascimento Moreira,

Yure Jefferson da Cruz do Nascimento

и другие.

Environmental Toxicology and Chemistry, Год журнала: 2025, Номер 44(1), С. 146 - 158

Опубликована: Янв. 1, 2025

Abstract The Amazon has environmental characteristics that make it unique, and the species inhabit have physiological features demonstrate their adaptation to an Amazonian context. ecosystems been undergoing transformations result from inadequate human actions, which placed biodiversity at limits of biological abilities. Therefore, is essential identify organisms reflect conditions environment, considering physiology these species, they are established as bioindicators for this region. fish Hyphessobrycon heterorhabdus distributed throughout lower middle basin. Aiming contribute establishment a bioindicator, we carried out first time its karyotyping, Illumina sequencing assembly nuclear genome mitogenome, in addition establishing cell line species. Individuals H. 48 chromosomes, number held line. Sequencing genomic generated draft useful recovering species-specific coding regulatory sequences. was responsive variables, reflecting vivo observations. Thus, possible present set resources (standard karyotype, centromeric marker, genome, line) applications relevance ecotoxicology. toolkit should further studies on response natural impacts region receiving.

Язык: Английский

Процитировано

0

Production of biologically active recombinant salmon calcitonin in Escherichia coli and fish cell line DOI
A. Nafeez Ahmed,

S. Abdul Majeed,

G. Taju

и другие.

Archives of Microbiology, Год журнала: 2025, Номер 207(2)

Опубликована: Янв. 25, 2025

Язык: Английский

Процитировано

0

Phytotherapeutic efficacy of Mitragyna parvifolia for acute dermatolymphangioadenitis (ADLA) DOI
Jefrillah Jebaseelan, A. Venkatesan,

Kalpana Manivannan R

и другие.

Journal of Parasitic Diseases, Год журнала: 2025, Номер unknown

Опубликована: Март 18, 2025

Язык: Английский

Процитировано

0

Rapid and Accurate Genotoxicity Assessment Using the Neutral Comet Assay in Cyprinus carpio Cells DOI Creative Commons

Byeonghyeon So,

Ji Ho Park, Minseon Kim

и другие.

Life, Год журнала: 2025, Номер 15(4), С. 603 - 603

Опубликована: Апрель 4, 2025

Genotoxins cause significant damage to the genetic material of aquatic organisms, requiring rapid and accurate assessment. Fish-derived cells sensitive genotoxins have proven be a useful tool for measuring genotoxicity, but long treatment times required measurement limit their application in situations testing. Previous studies shown that fish can kept unstarved up 6 h using media containing 1% FBS. In this study, FBS/6 parameter was used genotoxicity Therefore, assessment performed after only genotoxin medium The new method provided faster more data climbazole metolachlor than existing system 15% FBS/96 parameter. Furthermore, these advantages platform enabled determination various genotoxins, such as dibenz[a,h]anthracene ethoprophos. summary, we developed generate rapidly accurately. This will serve foundation many genotoxins.

Язык: Английский

Процитировано

0