Microbial Biotechnology,
Год журнала:
2024,
Номер
17(1)
Опубликована: Янв. 1, 2024
Abstract
Healthy
marine
ecosystems
are
paramount
for
Earth's
biodiversity
and
key
to
sustaining
the
global
economy
human
health.
The
effects
of
anthropogenic
activity
represent
a
pervasive
threat
productivity
ecosystems,
with
intensifying
environmental
stressors
such
as
climate
change
pollution
driving
occurrence
severity
microbial
diseases
that
can
devastate
jeopardise
food
security.
Despite
potentially
catastrophic
outcomes
diseases,
our
understanding
host‐pathogen
interactions
remains
an
understudied
aspect
both
microbiology
research,
especially
when
compared
depth
information
available
agricultural
systems.
Here,
we
identify
three
avenues
research
in
which
advance
disease
context
change,
make
positive
steps
towards
safeguarding
communities
future
generations.
Marine Biotechnology,
Год журнала:
2022,
Номер
25(1), С. 1 - 29
Опубликована: Ноя. 14, 2022
Abstract
Cultivated
meat,
also
known
as
cultured
or
cell-based
is
meat
produced
directly
from
animal
cells
rather
than
a
whole
animal.
and
seafood
have
been
proposed
means
of
mitigating
the
substantial
harms
associated
with
current
production
methods,
including
damage
to
environment,
antibiotic
resistance,
food
security
challenges,
poor
welfare,
and—in
case
seafood—overfishing
ecological
fishing
aquaculture.
Because
biomedical
tissue
engineering
research,
which
cultivated
draws
great
deal
inspiration,
has
thus
far
conducted
almost
exclusively
in
mammals,
suffers
lack
established
protocols
for
producing
complex
tissues
vitro.
At
same
time,
fish
such
zebrafish
Danio
rerio
widely
used
model
organisms
developmental
biology.
Therefore,
many
mechanisms
signaling
pathways
involved
formation
muscle,
fat,
other
relevant
are
relatively
well
understood
this
species.
The
processes
lesser
degree
aquatic
invertebrates.
This
review
discusses
differentiation
maturation
meat-relevant
cell
types
species
makes
recommendations
future
research
aimed
at
recapitulating
these
produce
shellfish.
Trends in Genetics,
Год журнала:
2023,
Номер
39(11), С. 830 - 843
Опубликована: Сен. 14, 2023
Aging
is
a
nearly
inescapable
trait
among
organisms
yet
lifespan
varies
tremendously
across
different
species
and
spans
several
orders
of
magnitude
in
vertebrates
alone.
This
vast
phenotypic
diversity
driven
by
distinct
evolutionary
trajectories
tradeoffs
that
are
reflected
patterns
diversification
constraint
organismal
genomes.
Age-specific
impacts
selection
also
shape
allele
frequencies
populations,
thus
impacting
disease
susceptibility
environment-specific
mortality
risk.
Further,
the
mutational
processes
spawn
this
genetic
both
germline
somatic
cells
strongly
influenced
age
life
history.
We
discuss
recent
advances
our
understanding
evolution
aging
at
organismal,
population,
cellular
scales,
highlight
outstanding
questions
remain
unanswered.
Environmental Toxicology and Pharmacology,
Год журнала:
2023,
Номер
98, С. 104072 - 104072
Опубликована: Янв. 20, 2023
The
potential
interactions
between
the
diverse
pollutants
that
can
be
released
into
environment
and
resulting
outcomes
are
a
challenging
issue
needs
to
further
examined.
This
in
vitro
study
was
aimed
assess
toxic
effects
caused
by
combined
exposure
tetrabromobisphenol
A,
flame
retardant
widely
used
frequently
detected
aquatic
matrices,
commercially
available
polystyrene
nanoparticles
as
reference
material
evaluate
nanoplastics
risks.
Our
results,
using
freshwater
fish
cell
lines
set
of
relevant
cytotoxicity
endpoints
including
viability,
oxidative
stress,
DNA
damage,
provide
additional
mechanistic
insights
could
help
fully
characterize
toxicity
profiles
A
nanoparticles.
Furthermore,
we
describe
subtle
changes
viability
well
generation
damage
after
coexposure
subcytotoxic
concentrations
tested
pollutants.
Aquaculture,
Год журнала:
2024,
Номер
593, С. 741302 - 741302
Опубликована: Июнь 28, 2024
Aquaculture
plays
a
crucial
role
in
meeting
the
growing
demand
for
seafood
worldwide.
However,
sustainability
of
aquaculture
practices
faces
challenges
from
environmental
pollutants
and
toxins.
Traditional
methods
assessing
aquatic
toxicity
often
rely
on
whole
organism
tests,
which
can
be
time-consuming,
expensive,
ethically
challenging.
In
recent
years,
utilization
fish
cell
lines
as
in-vitro
testing
models
toxicology
has
emerged
promising
alternative
approach.
Fish
offer
several
advantages,
including
cost-effectiveness,
scalability,
reduced
ethical
concerns.
This
review
paper
provides
an
overview
implementation
toxicology,
focusing
their
applications
contaminants,
mechanistic
studies,
biomarker
discovery.
Furthermore,
we
discuss
advantages
limitations
compared
to
traditional
tests
explore
future
perspectives
integrating
into
regulatory
frameworks.
Overall,
integration
holds
great
promise
enhancing
safety
face
increasing
pressures.
Environmental Toxicology and Chemistry,
Год журнала:
2025,
Номер
44(1), С. 146 - 158
Опубликована: Янв. 1, 2025
Abstract
The
Amazon
has
environmental
characteristics
that
make
it
unique,
and
the
species
inhabit
have
physiological
features
demonstrate
their
adaptation
to
an
Amazonian
context.
ecosystems
been
undergoing
transformations
result
from
inadequate
human
actions,
which
placed
biodiversity
at
limits
of
biological
abilities.
Therefore,
is
essential
identify
organisms
reflect
conditions
environment,
considering
physiology
these
species,
they
are
established
as
bioindicators
for
this
region.
fish
Hyphessobrycon
heterorhabdus
distributed
throughout
lower
middle
basin.
Aiming
contribute
establishment
a
bioindicator,
we
carried
out
first
time
its
karyotyping,
Illumina
sequencing
assembly
nuclear
genome
mitogenome,
in
addition
establishing
cell
line
species.
Individuals
H.
48
chromosomes,
number
held
line.
Sequencing
genomic
generated
draft
useful
recovering
species-specific
coding
regulatory
sequences.
was
responsive
variables,
reflecting
vivo
observations.
Thus,
possible
present
set
resources
(standard
karyotype,
centromeric
marker,
genome,
line)
applications
relevance
ecotoxicology.
toolkit
should
further
studies
on
response
natural
impacts
region
receiving.
Life,
Год журнала:
2025,
Номер
15(4), С. 603 - 603
Опубликована: Апрель 4, 2025
Genotoxins
cause
significant
damage
to
the
genetic
material
of
aquatic
organisms,
requiring
rapid
and
accurate
assessment.
Fish-derived
cells
sensitive
genotoxins
have
proven
be
a
useful
tool
for
measuring
genotoxicity,
but
long
treatment
times
required
measurement
limit
their
application
in
situations
testing.
Previous
studies
shown
that
fish
can
kept
unstarved
up
6
h
using
media
containing
1%
FBS.
In
this
study,
FBS/6
parameter
was
used
genotoxicity
Therefore,
assessment
performed
after
only
genotoxin
medium
The
new
method
provided
faster
more
data
climbazole
metolachlor
than
existing
system
15%
FBS/96
parameter.
Furthermore,
these
advantages
platform
enabled
determination
various
genotoxins,
such
as
dibenz[a,h]anthracene
ethoprophos.
summary,
we
developed
generate
rapidly
accurately.
This
will
serve
foundation
many
genotoxins.