Опубликована: Ноя. 21, 2024
Язык: Английский
Опубликована: Ноя. 21, 2024
Язык: Английский
Healthcare, Год журнала: 2024, Номер 12(24), С. 2587 - 2587
Опубликована: Дек. 22, 2024
Federated learning (FL) is revolutionizing healthcare by enabling collaborative machine across institutions while preserving patient privacy and meeting regulatory standards. This review delves into FL's applications within smart health systems, particularly its integration with IoT devices, wearables, remote monitoring, which empower real-time, decentralized data processing for predictive analytics personalized care. It addresses key challenges, including security risks like adversarial attacks, poisoning, model inversion. Additionally, it covers issues related to heterogeneity, scalability, system interoperability. Alongside these, the highlights emerging privacy-preserving solutions, such as differential secure multiparty computation, critical overcoming limitations. Successfully addressing these hurdles essential enhancing efficiency, accuracy, broader adoption in healthcare. Ultimately, FL offers transformative potential secure, data-driven promising improved outcomes, operational sovereignty ecosystem.
Язык: Английский
Процитировано
8Optics & Laser Technology, Год журнала: 2024, Номер 183, С. 112246 - 112246
Опубликована: Дек. 8, 2024
Язык: Английский
Процитировано
6Neural Computing and Applications, Год журнала: 2025, Номер unknown
Опубликована: Март 19, 2025
Язык: Английский
Процитировано
0Computer Science Review, Год журнала: 2025, Номер 57, С. 100751 - 100751
Опубликована: Апрель 4, 2025
Язык: Английский
Процитировано
0Information Fusion, Год журнала: 2025, Номер unknown, С. 103180 - 103180
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Asia-Pacific Journal of Clinical Oncology, Год журнала: 2025, Номер unknown
Опубликована: Апрель 17, 2025
ABSTRACT Background The cell division cycle‐associated (CDCA) genes regulate key cellular processes like cycle progression and division. This study evaluates the diagnostic clinical relevance of CDCA in breast cancer. Methodology Breast cancer normal lines were cultured analyzed for gene expression using RT‐qPCR further validated public databases. Functional assays, including proliferation, colony formation, wound healing, performed following siRNA‐mediated knockdown CDCA2 CDCA3. Mutational, CNV, methylation, survival analyses, along with miRNA regulation PPI network construction, conducted to explore role progression. Results Our findings revealed significant upregulation compared controls, all these exhibiting highest potential based on AUC values ROC analysis. Pathological stage analysis indicated that CDCA5 CDCA7 significantly varied across different stages. Mutational showed had mutation rate, missense mutations being most common. CNV amplification events several genes, particularly CDCA2, CDCA3, CDCA4, CDCA7. Promoter methylation hypomethylation cancer, which correlated negatively their expression. Survival demonstrated high CDCA5, CDCA7, CDCA8 was associated worse overall survival, highlighting prognostic significance. Furthermore, immune infiltration correlations between types, suggesting a modulation. identified specific miRNAs targeting showing as biomarkers. Lastly, CDCA3 cells reduced migration, indicating critical roles tumor growth metastasis. Conclusion highlights promising biomarkers Their correlates poor impairs growth, emphasizing therapeutic targets. These suggest could be integrated into practice improved management. Clinical trial number Not applicable.
Язык: Английский
Процитировано
0Communications in Nonlinear Science and Numerical Simulation, Год журнала: 2025, Номер unknown, С. 108955 - 108955
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0Global Transitions, Год журнала: 2025, Номер unknown
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Май 20, 2025
Язык: Английский
Процитировано
0Discover Artificial Intelligence, Год журнала: 2025, Номер 5(1)
Опубликована: Май 26, 2025
Язык: Английский
Процитировано
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