Toward cancer detection by label-free microscopic imaging in oncological surgery: techniques, instrumentation and applications
Micron,
Год журнала:
2025,
Номер
191, С. 103800 - 103800
Опубликована: Фев. 6, 2025
This
review
examines
the
clinical
application
of
label-free
microscopy
and
spectroscopy,
which
are
based
on
optical
signals
emitted
by
tissue
components.
Over
past
three
decades,
a
variety
techniques
have
been
investigated
with
aim
developing
an
in
situ
histopathology
method
that
can
rapidly
accurately
identify
tumor
margins
during
surgical
procedures.
These
be
divided
into
two
groups.
One
group
encompasses
exploiting
linear
signals,
includes
infrared
Raman
microspectroscopy,
autofluorescence
microscopy.
The
second
nonlinear
including
harmonic
generation,
coherent
scattering,
multiphoton
Some
these
methods
provide
comparable
information,
while
others
complementary.
However,
all
them
distinct
advantages
disadvantages
due
to
their
inherent
nature.
first
part
provides
explanation
underlying
physics
excitation
mechanisms
description
instrumentation.
It
also
covers
endomicroscopy
data
analysis,
important
for
understanding
current
limitations
implementing
settings.
describes
imaging
improve
oncological
surgery
focus
brain
tumors
selected
gastrointestinal
cancers,
critical
assessment
state
translation
practice.
Finally,
potential
confocal
laser
acquisition
is
discussed
context
immediate
applications.
Язык: Английский
On-line adapted islands SERS Chip for quantitatively sensing H2S molecules in food spoilage
Food Chemistry,
Год журнала:
2025,
Номер
478, С. 143618 - 143618
Опубликована: Март 3, 2025
Язык: Английский
Accuracy of Raman spectroscopy in discriminating normal brain tissue from brain tumor: A systematic review and meta-analysis
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy,
Год журнала:
2024,
Номер
329, С. 125518 - 125518
Опубликована: Ноя. 30, 2024
Язык: Английский