Control of spiral waves in myocardial tissue by optogenetics and temperature DOI Creative Commons
Yipeng Hu, Qianming Ding, Yonghong Wu

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Июнь 20, 2024

Abstract Optogenetics as an emerging technology can eliminate spiral waves in myocardial tissue. The heat generated during illumination of tissue is overlooked influence. Even small fluctuations temperature may affect the action potentials cardiomyocyte. In this paper, a minimal ventricular model and simplified optogenetics are employed to study effects generation by on elimination waves. Luo-Rudy Channelrhodospin-2 light-sensitive ion channel used validate our conclusions. Weinduce drift through inhomogeneities discrete gradients illumination. inhomogeneity caused gradient inhibit Spiral medium be induced more efficiently controlling changes We emphasized importance factors optogenetic experiments, hoping that results could provide guidance for its clinical applications.

Язык: Английский

Community modularity structure promotes the evolution of phase clusters and chimeralike states DOI
Dong Yu, Xuening Li, Xueqin Wang

и другие.

Physical review. E, Год журнала: 2025, Номер 111(3)

Опубликована: Март 24, 2025

Community modularity structure is widely observed across various brain scales, reflecting a balance between information processing efficiency and neural wiring metabolic efficiency. Revealing the relationship community function facilitates our further understanding of brain. Here, we construct an adaptive network (ANN) consisting leaky integrate-and-fire neurons with adaptivity governed by spike-time-dependent plasticity rules. The ANN demonstrates diverse dynamic collective behaviors, including traveling waves dominated initial states, phase-cluster formations, chimeralike states. In addition to functional clustering, spontaneously organizes into structures characterized densely interconnected modules sparse interconnections. Neurons within synchronize, while those remain asynchronous, forming By encoding rhythms, segments asynchronous synchronous structural modules, leading These findings provide evidence supporting perspective that emerges from influenced in complex processes.

Язык: Английский

Процитировано

1
Adaptive electric shocks control and elimination of spiral waves using dynamic learning based techniques DOI
Qianming Ding, Yonghong Wu, Weifang Huang

и другие.

Nonlinear Dynamics, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 17, 2024

Язык: Английский

Процитировано

5
Control of spiral waves in myocardial tissue by optogenetics and temperature DOI
Yipeng Hu, Qianming Ding, Yonghong Wu

и другие.

Nonlinear Dynamics, Год журнала: 2024, Номер 112(21), С. 19421 - 19439

Опубликована: Июль 27, 2024

Язык: Английский

Процитировано

4
Elimination of reentry spiral waves using adaptive optogenetical illumination based on dynamic learning techniques DOI
Qianming Ding, Yipeng Hu, Yong Wu

и другие.

Chaos Solitons & Fractals, Год журнала: 2024, Номер 191, С. 115846 - 115846

Опубликована: Ноя. 30, 2024

Язык: Английский

Процитировано

3
Delay-induced multiple firing resonance in a coupled neuronal motif DOI

Hongfang Tan,

S. Xian

Nonlinear Dynamics, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Язык: Английский

Процитировано

0
Control of spiral waves in myocardial tissue by optogenetics and temperature DOI Creative Commons
Yipeng Hu, Qianming Ding, Yonghong Wu

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Июнь 20, 2024

Abstract Optogenetics as an emerging technology can eliminate spiral waves in myocardial tissue. The heat generated during illumination of tissue is overlooked influence. Even small fluctuations temperature may affect the action potentials cardiomyocyte. In this paper, a minimal ventricular model and simplified optogenetics are employed to study effects generation by on elimination waves. Luo-Rudy Channelrhodospin-2 light-sensitive ion channel used validate our conclusions. Weinduce drift through inhomogeneities discrete gradients illumination. inhomogeneity caused gradient inhibit Spiral medium be induced more efficiently controlling changes We emphasized importance factors optogenetic experiments, hoping that results could provide guidance for its clinical applications.

Язык: Английский

Процитировано

0