Response to letter to the editor “Hypopituitarism and COVID-19, what else?”

Pituitary, Год журнала: 2025, Номер 28(1)

Опубликована: Фев. 1, 2025

Язык: Английский

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Central Hypothyroidism with Low TSH Comparing to Normal TSH Is Associated with More Advanced Pituitary Disease and Less Favorable Metabolic Profile

Metabolites, Год журнала: 2025, Номер 15(2), С. 125 - 125

Опубликована: Фев. 13, 2025

Background: Central hypothyroidism is characterized by either decreased TSH or, more commonly, normal TSH. This study aims to check whether this biochemical difference related the severity of pituitary disease, metabolic processes and general well-being. Methods: A retrospective analysis was performed on 108 inpatients with hypopituitarism, aged 18-80, hospitalized (1 January 2020, through 31 December 2022) in Department Endocrinology Metabolic Diseases, Medical University Lodz, Poland. Hypopituitary patients central (n = 90) were divided into two subgroups: below ranges (low TSH; n 52) reference (normal 38). Results: Among hypothyroidism, surgical treatment due disease commonly those low than (65 vs. 42%, p 0.010). Expectedly, five deficiencies diagnosed (46 13%, 0.001). In a regression analysis, ACTH concentration only independent determinant negatively associated (also after limiting non-treated patients). Regarding lipid profile, HDL cholesterol occurred (44% 23%; 0.033), which also observed limitation (47% 21%; 0.013). Conclusions: Low advanced less favorable profile.

Язык: Английский

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Hypopituitarism and COVID-19, what else?

Pituitary, Год журнала: 2024, Номер 28(1)

Опубликована: Дек. 21, 2024

Язык: Английский

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