A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment
Mycobiology,
Год журнала:
2024,
Номер
52(6), С. 335 - 387
Опубликована: Ноя. 1, 2024
Fungi
and
their
natural
products,
like
secondary
metabolites,
have
gained
a
huge
demand
in
the
last
decade
due
to
increasing
applications
healthcare,
environmental
cleanup,
biotechnology-based
industries.
The
fungi
produce
these
metabolites
(SMs)
during
different
phases
of
growth,
which
are
categorized
into
terpenoids,
alkaloids,
polyketides,
non-ribosomal
peptides.
These
SMs
exhibit
significant
biological
activity,
contributes
formulation
novel
pharmaceuticals,
biopesticides,
bioremediation
agents.
Nowadays,
fungal-derived
widely
used
food
beverages,
for
fermentation,
preservatives,
protein
sources,
dairy
In
it
is
being
as
an
antimicrobial,
anticancer,
anti-inflammatory,
immunosuppressive
drug.
usage
modern
tools
biotechnology
can
achieve
increase
large-scale
production.
present
review
comprehensively
analyses
diversity
fungal
along
with
emerging
agriculture,
sustainability,
nutraceuticals.
Here,
authors
reviewed
recent
advancements
genetic
engineering,
metabolic
pathway
manipulation,
synthetic
biology
improve
production
yield
SMs.
Advancement
fermentation
techniques,
bioprocessing,
co-cultivation
approaches
Investigators
further
highlighted
importance
omics
technologies
understanding
regulation
biosynthesis
SMs,
offers
drug
discovery
sustainable
agriculture.
Finally,
addressed
potential
manipulation
biotechnological
innovations
exploitation
commercial
benefits.
Язык: Английский
Production of Phytase by Penicillium oxalicum in Solid State Fermentation Exhibiting Hydrolysis of Phytates and Haloperoxidase Activity
Indian Journal of Microbiology,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 18, 2025
Язык: Английский
Fungal Phytases as Useful Tools in Agricultural Practices
Agronomy,
Год журнала:
2024,
Номер
14(12), С. 3029 - 3029
Опубликована: Дек. 19, 2024
In
order
to
meet
the
ever-growing
needs
of
society,
modern
agriculture
must
develop
sustainable
farming
and
livestock
production.
Crops
need
phosphorus,
a
macronutrient
found
in
soils,
but
they
are
only
able
utilize
small
quantities
it.
Chemical
phosphate
fertilizers
ineffective
environmentally
harmful.
The
use
microorganisms
(bacteria,
yeast,
filamentous
fungi,
microalgae)
that
synthesize
phytases
is
promising
friendly
alternative
chemical
fertilizers.
Phytases
also
needed
as
feed
additives
animal
husbandry
overcome
phosphorus
deficiency
for
growth
development.
phosphatases
catalyze
release
from
phytate
by
stepwise
hydrolysis.
broad
substrate
specificity,
optimal
pH
range,
higher
thermal
stability,
specific
efficiency
fungal
make
them
interesting
enzymes
agricultural
applications.
They
improve
stimulate
development
plants
animals
releasing
inorganic
producing
siderophores,
organic
acids,
hydrogen
cyanide,
ammonia,
phytohormones.
crucial
enhancing
decreasing
waste’s
environmental
effects.
This
paper
addresses
key
challenges
farming,
such
inefficient
utilization
soil
harm
caused
fertilizers,
provides
comprehensive
overview
recent
advances
research
phytases.
Available
scientific
data
have
been
synthesized
highlight
potential
phytase
agriculture.
review
outlines
areas
future
research,
including
variants
with
improved
functionality.
integration
into
practices
underlined,
contrast
previously
published
work
focused
primarily
on
their
biochemical
properties.
offers
new
insight
possible
applications
micromycete
critical
factor
future.
Язык: Английский