Wastewater surveillance to infer COVID-19 transmission: A systematic review

The Science of The Total Environment, Год журнала: 2021, Номер 804, С. 150060 - 150060

Опубликована: Сен. 8, 2021

Successful detection of SARS-COV-2 in wastewater suggests the potential utility wastewater-based epidemiology (WBE) for COVID-19 community surveillance. This systematic review aims to assess performance surveillance as early warning system transmission. A search was conducted PubMed, Medline, Embase and WBE Consortium Registry according PRISMA guidelines relevant articles published until 31st July 2021. Relevant data were extracted summarized. Quality each paper assessed using an assessment tool adapted from Bilotta et al.'s environmental science. Of 763 studies identified, 92 distributed across 34 countries shortlisted qualitative synthesis. total 26,197 samples collected between January 2020 May 2021 various locations serving population ranging 321 11,400,000 inhabitants. Overall sample positivity moderate at 29.2% all examined settings with spike (S) gene having maximum rate positive detections nucleocapsid (N) being most targeted. Wastewater signals preceded confirmed cases by up 63 days, 13 reporting before first detected community. At least 50 reported association viral load cases. While cannot replace large-scale diagnostic testing, it can complement clinical providing signs transmission more active public health responses. However, standardized validated methods are required along risk analysis modelling understand dynamics outbreaks.

Язык: Английский

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Wastewater based epidemiology as a public health resource in low- and middle-income settings.

Environmental Pollution, Год журнала: 2024, Номер 351, С. 124045 - 124045

Опубликована: Апрель 25, 2024

In the face of emerging and re-emerging diseases, novel innovative approaches to population scale surveillance are necessary for early detection quantification pathogens. The last decade has seen rapid development wastewater environmental (WES) address public health challenges, which led establishment wastewater-based epidemiology (WBE) being deployed monitor a range hazards. WBE exploits fact that excretions secretions from urine, gut discharged in wastewater, particularly sewage, such sampling sewage systems provides an warning system disease outbreaks by providing indication pathogen circulation. While been mainly used locations with networked systems, here we consider its value less connected populations typical lower-income settings, assess opportunity afforded pit latrines sample communities localities. We propose where struggle access diagnostic facilities, despite several additional unconnected remains important means large relatively cost-effective manner.

Язык: Английский

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A review on detection of SARS-CoV-2 RNA in wastewater in light of the current knowledge of treatment process for removal of viral fragments

Journal of Environmental Management, Год журнала: 2021, Номер 299, С. 113563 - 113563

Опубликована: Авг. 19, 2021

Язык: Английский

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Dependency of sanitation infrastructure on the discharge of faecal coliform and SARS-CoV-2 viral RNA in wastewater from COVID and non-COVID hospitals in Dhaka, Bangladesh

The Science of The Total Environment, Год журнала: 2023, Номер 867, С. 161424 - 161424

Опубликована: Янв. 7, 2023

Язык: Английский

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On the Critical Role of Human Feces and Public Toilets in the Transmission of COVID-19: Evidence from China

Sustainable Cities and Society, Год журнала: 2021, Номер 75, С. 103350 - 103350

Опубликована: Сен. 11, 2021

Язык: Английский

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Key SARS-CoV-2 Mutations of Alpha, Gamma, and Eta Variants Detected in Urban Wastewaters in Italy by Long-Read Amplicon Sequencing Based on Nanopore Technology

Water, Год журнала: 2021, Номер 13(18), С. 2503 - 2503

Опубликована: Сен. 13, 2021

The emergence of SARS-CoV-2 variants concern (VOCs) and interest (VOIs) poses an increased risk to global public health underlines the need prioritise monitoring research better respond COVID-19 pandemic. Wastewater can be used monitor spread track variants. A long read amplicon sequencing approach based on Oxford Nanopore technology, targeting spike protein, was applied detect in sewage samples collected central Italy April 2021. Next-generation performed three pooled samples. For variant identification, two approaches–clustering (unsupervised) classification (supervised)–were implemented, resulting detection VOCs one VOI. Key mutations Alpha (B.1.1.7) were detected all pools, accounting for vast majority NGS reads. In different Gamma (P.1) Eta (B.1.525) also detected, 22.4%, 1.3% total reads sample, respectively. Results agreement with data circulation at time wastewater sample collection. each variant, addition signature key mutations, other less common including amino acid substitutions S98F E484K cluster (alone combined), S151I cluster. present study show that long-read nanopore technology successfully explore diversity samples, where multiple present, is sensitive enough low abundance conclusion, help discover a community early emerging clinically relevant or

Язык: Английский

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Dynamics of SARS-CoV-2 in wastewater in three districts of the Buenos Aires metropolitan region, Argentina, throughout nine months of surveillance: A pilot study

The Science of The Total Environment, Год журнала: 2021, Номер 800, С. 149578 - 149578

Опубликована: Авг. 12, 2021

Язык: Английский

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Monitoring COVID‐19 through SARS‐CoV‐2 quantification in wastewater: progress, challenges and prospects

Microbial Biotechnology, Год журнала: 2021, Номер 15(6), С. 1719 - 1728

Опубликована: Дек. 14, 2021

Summary Wastewater‐Based Epidemiology (WBE) is widely used to monitor the progression of current SARS‐CoV‐2 pandemic at local levels. In this review, we address different approaches steps needed for surveillance: sampling wastewaters (WWs), concentrating virus from samples and quantifying them by qPCR, focusing on main limitations methodologies used. Factors that can influence monitoring in WWs include: (i) physical parameters as temperature hamper detection warm seasons tropical regions, (ii) timetables, being composite Moore swabs less variable more sensitive approaches, (iii) concentration need be feasible practicable simpler laboratories (iv) should tend use faster cost‐effective procedures. The efficiency WW treatments variants are also addressed. Furthermore, discuss development common standardized protocols, although these must versatile enough comprise variations among target communities. WBE screening risk populations will allow prediction future outbreaks, thus alerting authorities implement early action measurements.

Язык: Английский

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Absence of virological and epidemiological evidence that SARS-CoV-2 poses COVID-19 risks from environmental fecal waste, wastewater and water exposures

Journal of Water and Health, Год журнала: 2021, Номер 20(1), С. 126 - 138

Опубликована: Дек. 10, 2021

Abstract This review considers evidence for infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presence and COVID-19 infection illness resulting from exposure to environmental fecal wastes waters. There is no documented that (1) infectious, replication-capable SARS-CoV-2 present in wastes, wastewater or water, (2) well-documented epidemiological of infection, death has never been reported these media. transmitted mainly by direct personal contact secretions as airborne droplets aerosols, less so respiratory-secreted fomites via (touch) exposures. While often infects the gastrointestinal tract infected people, its virus waters documented. only rare unquantified recently shed feces hospital patients. The human infectivity dose–response relationship unknown, thereby making it impossible estimate evidence-based quantitative health effects assessments microbial risk assessment methods requiring both known data. World Health Organization, Water Environment Federation, US Centers Disease Control Prevention others do not consider sources causing illness.

Язык: Английский

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Transmission of SARS-CoV-2 infections and exposure in surfaces, points and wastewaters: A global one health perspective

Case Studies in Chemical and Environmental Engineering, Год журнала: 2022, Номер 5, С. 100184 - 100184

Опубликована: Янв. 24, 2022

The persistence of SARS-CoV-2 or its RNA on surfaces, points, wastewaters may increase the risk transmission this virus. Therefore, we conducted review to discuss places and surfaces with highest potential for infection spread Several common public areas, hospitals, elevators, transport, local markets, such as toilets, door handles, untreated treated wastewaters, wastewater plants, washrooms are also considered major points spreading SARS-CoV-2. Highly contaminated often have materials contain items made which virus can persist (e.g., metal, wood, plastic). For example, exist up 4 days doorknobs by those materials. transports, crowding enclosed spaces source transmission. measures using copper alloy instead metal disinfectants, suitable personal protective equipment been suggested. Our research could be basis help develop studies existence transmissibility well take prevent limit harmful effects COVID-19 pandemic.

Язык: Английский

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