Ferroptosis Induced by Pollutants: An Emerging Mechanism in Environmental Toxicology DOI

Lili Yang,

Xiaoming Cai,

Ruibin Li

и другие.

Environmental Science & Technology, Год журнала: 2024, Номер 58(5), С. 2166 - 2184

Опубликована: Янв. 26, 2024

Environmental pollutants have been recognized for their ability to induce various adverse outcomes in both the environment and human health, including inflammation, apoptosis, necrosis, pyroptosis, autophagy. Understanding these biological mechanisms has played a crucial role risk assessment management efforts. However, recent identification of ferroptosis as form programmed cell death emerged critical mechanism underlying pollutant-induced toxicity. Numerous studies demonstrated that fine particulates, heavy metals, organic substances can trigger ferroptosis, which is closely intertwined with lipid, iron, amino acid metabolism. Given growing evidence linking severe diseases such heart failure, chronic obstructive pulmonary disease, liver injury, Parkinson's Alzheimer's cancer, it imperative investigate ferroptosis. In this review, we comprehensively analyze pathways intricate signaling molecules elucidate integration into driving braking axes. Furthermore, discuss potential hazards associated organs four representative animal models. Finally, provide an outlook on future research directions strategies aimed at preventing By enhancing our understanding novel developing effective preventive measures, mitigate effects environmental safeguard health.

Язык: Английский

Microplastics in agroecosystems-impacts on ecosystem functions and food chain DOI
Emmanuel Sunday Okeke, Charles Obinwanne Okoye, Edidiong Okokon Atakpa

и другие.

Resources Conservation and Recycling, Год журнала: 2021, Номер 177, С. 105961 - 105961

Опубликована: Окт. 14, 2021

Язык: Английский

Процитировано

209

Physisorption and Chemisorption Mechanisms Influencing Micro (Nano) Plastics-Organic Chemical Contaminants Interactions: A Review DOI Creative Commons

Omowumi D. Agboola,

Nsikak U. Benson

Frontiers in Environmental Science, Год журнала: 2021, Номер 9

Опубликована: Май 28, 2021

Microplastics, which serve as sources and vector transport of organic contaminants in both terrestrial marine environments, are emerging micropollutants increasing concerns due to their potential harmful impacts on the environment, biota human health. Microplastic particles have a higher affinity for hydrophobic high surface area-to-volume ratio, particularly aqueous conditions. However, recent findings shown that concentrations adsorbed microplastic surfaces, well fate through distribution ecological risks, largely influenced by prevailing environmental factors physicochemical properties aquatic environment. Therefore, this review article draws scientific literature discuss inherent polymers typically used plastics different contaminants, compositions, factors, polymeric influence variability sorption capacities. Some specific points discussed (a) an appraisal types, composition environment; (b) critical assessment mechanisms major influencing contaminants-micro (nano) (MNPs) interactions; (c) evaluation capacities chemical MNPs terms characteristics including hydrophobicity, Van der Waals forces, π–π bond, electrostatic, hydrogen bond (d) overview dynamics behind microplastics-organic interactions using kinetic isothermal models. Furthermore, insights into future areas research gaps been highlighted.

Язык: Английский

Процитировано

198

Micro- and nano-plastics (MNPs) as emerging pollutant in ground water: Environmental impact, potential risks, limitations and way forward towards sustainable management DOI
Vikas Kumar, Ekta Singh, Shivani Singh

и другие.

Chemical Engineering Journal, Год журнала: 2023, Номер 459, С. 141568 - 141568

Опубликована: Янв. 27, 2023

Язык: Английский

Процитировано

134

Risks of Covid-19 face masks to wildlife: Present and future research needs DOI Open Access
Ana L. Patrício Silva, Joana C. Prata, Catherine Mouneyrac

и другие.

The Science of The Total Environment, Год журнала: 2021, Номер 792, С. 148505 - 148505

Опубликована: Июнь 17, 2021

Язык: Английский

Процитировано

125

Microbial Colonization and Degradation of Microplastics in Aquatic Ecosystem: A Review DOI
Sujata Mishra,

Subhashree Swain,

Monalisa Sahoo

и другие.

Geomicrobiology Journal, Год журнала: 2021, Номер 39(3-5), С. 259 - 269

Опубликована: Окт. 14, 2021

A major apprehension is over microplastic pollution in the aquatic environment. These microplastics particles represent a novel medium environment, providing substratum for various organic contaminants and colonization of microorganisms. Microorganisms form biofilm on exterior pollutants, consequential region known as plastisphere, which they interrelate generate acid different enzymes degradation. The use microbes degradation has become contentious exit indication society focuses more environmentally friendly reduction methods. After both substantial elemental degradation, biodegradation occurs, weakening arrangement polymers. Natural resource have significant effect plastic waste current review article discusses microbial present ecosystems processes involved. While studying considering how these now turn out to be recent environmental position within environments, we emphasized significance microbial-assisted this article.

Язык: Английский

Процитировано

116

Release of Microplastics from Discarded Surgical Masks and Their Adverse Impacts on the Marine Copepod Tigriopus japonicus DOI Creative Commons
Jiaji Sun, Shiyi Yang, Guang‐Jie Zhou

и другие.

Environmental Science & Technology Letters, Год журнала: 2021, Номер 8(12), С. 1065 - 1070

Опубликована: Ноя. 11, 2021

Surgical masks (SMs) are the most commonly used personal protective equipment during COVID-19 pandemic. Due to their vast use and inappropriate disposal worldwide, SMs could potentially cause serious microplastic (MP) pollution in coastal marine environments. This study aimed investigate kinetic release of MPs from polypropylene (PP-SMs) seawater evaluate chronic toxicity released copepod Tigriopus japonicus. On basis results our available relevant data, we estimated that discarded throughout year 2020 would lead >1370 trillion entering environment globally, with a rate 396 billion per day. Our also demonstrated copepods ingested PP-SMs, causing significant decline fecundity. The clearly suggest improperly have long-term domino effect on ecosystems. To minimize risk this emerging threat, better environmental management, policy, law enforcement for ensuring proper deemed be necessary.

Язык: Английский

Процитировано

115

PHA-Based Bioplastic: a Potential Alternative to Address Microplastic Pollution DOI Open Access
Shiva Aley Acharjee, Pranjal Bharali, Bhagyudoy Gogoi

и другие.

Water Air & Soil Pollution, Год журнала: 2022, Номер 234(1)

Опубликована: Дек. 29, 2022

Язык: Английский

Процитировано

99

Microplastics in Wastewater by Washing Polyester Fabrics DOI Open Access
Ana Šaravanja, Tanja Pušić, Tihana Dekanić

и другие.

Materials, Год журнала: 2022, Номер 15(7), С. 2683 - 2683

Опубликована: Апрель 6, 2022

Microplastics have become one of the most serious environmental hazards today, raising fears that concentrations will continue to rise even further in near future. Micro/nanoparticles are formed when plastic breaks down into tiny fragments due mechanical or photochemical processes. everywhere, and they a strong tendency interact with ecosystem, putting biogenic fauna flora at risk. Polyester (PET) polyamide (PA) two important synthetic fibres, accounting for about 60% total world fibre production. Synthetic fabrics now widely used clothing, carpets, variety other products. During manufacturing cleaning process, textiles potential release microplastics environment. The focus this paper is explore main sources microplastic pollution environment, providing an overview washable polyester materials.

Язык: Английский

Процитировано

96

Impacts of microplastics on immunity DOI Creative Commons
Wenjie Yang, Nahar Jannatun,

Yanqiao Zeng

и другие.

Frontiers in Toxicology, Год журнала: 2022, Номер 4

Опубликована: Сен. 27, 2022

Most disposable plastic products are degraded slowly in the natural environment and continually turned to microplastics (MPs) nanoplastics (NPs), posing additional environmental hazards. The toxicological assessment of MPs for marine organisms mammals has been reported. Thus, there is an urgent need be aware harm human immune system more studies about immunological assessments. This review focuses on how produced they may interact with our body, particularly their responses immunotoxicity. can taken up by cells, thus disrupting intracellular signaling pathways, altering homeostasis finally causing damage tissues organs. generation reactive oxygen species mainly mechanisms after MP exposure, which further induce production danger-associated molecular patterns (DAMPs) associate processes toll-like receptors (TLRs) disruption, cytokine production, inflammatory cells. effectively cell membranes or proteins form a protein-corona, combine external pollutants, chemicals, pathogens greater toxicity strong adverse effects. A comprehensive research immunotoxicity effects MPs, including various chemical compositions, shapes, sizes, combined exposure concentrations, worth studied. Therefore, it urgently needed elucidate hazards risks humans that exposed MPs.

Язык: Английский

Процитировано

87

Current research trends on cosmetic microplastic pollution and its impacts on the ecosystem: A review DOI

Yuwen Zhou,

Veeramuthu Ashokkumar, Ayodeji Amobonye

и другие.

Environmental Pollution, Год журнала: 2023, Номер 320, С. 121106 - 121106

Опубликована: Янв. 18, 2023

Язык: Английский

Процитировано

83