Photo Energy Transfer-Enabled Thiosulfinylation of Alkynes for Asymmetric Synthesis of Sultims
Organic Letters,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 25, 2024
An
asymmetric
and
highly
practical
thiosulfinylation
of
alkynes
is
established
for
the
synthesis
sultim
derivatives.
The
disclosed
platform
featured
broad
substrate
scope
group
tolerance
diverse
biologically
important
molecules
under
mild
operationally
simple
conditions.
Notably,
obtained
chiral
sulfinyl
derivatives
have
demonstrated
their
potential
application
in
further
gram-scale
product
derivatizations,
providing
a
chance
drug
discovery.
Язык: Английский
Recent Advances in the Synthesis of Cyclic Sulfone Compounds with Potential Biological Activity
Molecules,
Год журнала:
2024,
Номер
29(24), С. 5868 - 5868
Опубликована: Дек. 12, 2024
In
recent
years,
cyclic
sulfone
compounds,
a
subset
of
biologically
active
heterocyclic
have
gained
considerable
attention
due
to
their
potential
in
the
development
novel
pharmaceutical
ingredients.
This
review
focuses
on
identifying
simple,
mild,
environmentally
friendly,
and
efficient
synthesis
methods.
Various
catalytic
approaches
for
compounds
are
systematically
reviewed,
highlighting
advantages
applications
development.
Язык: Английский