Photocatalytic C–H Trifluoroethoxylation of (Hetero)arenes DOI
Mingxi Chen, Jingjing Ling, Keguang Cheng

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Фев. 20, 2025

The trifluoroethoxy group (OCH2CF3) is a valuable motif prevalent in pharmaceuticals and agrichemicals. Herein, we present simple radical trifluoroethoxylation method that enables nondirected functionalization of C-H bonds broad array substrates, providing access to (hetero)aryl trifluoroethyl ethers. current protocol tolerates variety synthetically pharmacologically relevant functional groups. Applicability also demonstrated through the late-stage biorelevant molecules marketing drugs.

Язык: Английский

Photocatalytic C–H Trifluoroethoxylation of (Hetero)arenes DOI
Mingxi Chen, Jingjing Ling, Keguang Cheng

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Фев. 20, 2025

The trifluoroethoxy group (OCH2CF3) is a valuable motif prevalent in pharmaceuticals and agrichemicals. Herein, we present simple radical trifluoroethoxylation method that enables nondirected functionalization of C-H bonds broad array substrates, providing access to (hetero)aryl trifluoroethyl ethers. current protocol tolerates variety synthetically pharmacologically relevant functional groups. Applicability also demonstrated through the late-stage biorelevant molecules marketing drugs.

Язык: Английский

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