Molecular Biology and Evolution,
Год журнала:
2023,
Номер
40(12)
Опубликована: Дек. 1, 2023
Abstract
Animals
consume
a
wide
variety
of
food
sources
to
adapt
different
environments.
However,
the
genetic
mechanisms
underlying
acquisition
evolutionarily
novel
feeding
morphology
remain
largely
unknown.
While
nematode
Caenorhabditis
elegans
feeds
on
bacteria,
satellite
species
Pristionchus
pacificus
exhibits
predatory
behavior
toward
other
nematodes,
which
is
an
habit.
Here,
we
found
that
astacin
metalloprotease
Ppa-NAS-6
required
for
killing
by
P.
pacificus.
Ppa-nas-6
mutants
were
defective
in
predation-associated
characteristics,
specifically
tooth
morphogenesis
and
movement
during
predation.
Comparison
expression
patterns
rescue
experiments
nas-6
C.
suggested
alteration
spatial
NAS-6
may
be
vital
acquiring
predation-related
traits.
Reporter
analysis
promoter
revealed
was
caused
evolutionary
changes
cis-
trans-regulatory
elements.
This
study
suggests
co-option
involved
morphology.
The Innovation,
Год журнала:
2023,
Номер
4(3), С. 100434 - 100434
Опубликована: Апрель 28, 2023
DNA
methylation
is
an
epigenetic
modification
that
plays
a
crucial
role
in
various
regulatory
processes,
including
gene
expression
regulation,
transposable
element
repression,
and
genomic
imprinting.
However,
most
studies
on
have
been
conducted
humans
other
model
species,
whereas
the
dynamics
of
across
mammals
remain
poorly
explored,
limiting
our
understanding
epigenomic
evolution
evolutionary
impacts
conserved
lineage-specific
methylation.
Here,
we
generated
gathered
comparative
data
from
13
mammalian
two
marsupial
to
demonstrate
critical
roles
several
aspects
species
trait
evolution.
We
found
species-specific
promoters
noncoding
elements
correlates
with
traits
such
as
body
patterning,
indicating
might
help
establish
or
maintain
interspecies
differences
regulation
shape
phenotypes.
For
broader
view,
investigated
histories
88
known
imprinting
control
regions
identify
their
origins.
By
analyzing
features
newly
identified
potential
imprints
all
studied
mammals,
may
function
embryonic
development
through
binding
specific
transcription
factors.
Our
findings
show
complex
interaction
between
genome
epigenome
significant
impact
evolution,
suggesting
epigenomics
should
be
incorporated
develop
unified
theory.
Annual Review of Animal Biosciences,
Год журнала:
2023,
Номер
12(1), С. 69 - 89
Опубликована: Окт. 20, 2023
Giant
pandas
and
red
are
endangered
species
with
similar
specialized
bamboo
diet
partial
sympatric
distribution
in
China.
Over
the
last
two
decades,
rapid
development
of
genomics
metagenomics
research
on
these
has
enriched
our
knowledge
their
biology,
ecology,
physiology,
genetics,
evolution,
which
is
crucial
useful
for
conservation.
We
describe
evolutionary
history,
endangerment
processes,
genetic
diversity,
population
structure
wild
giant
(Chinese
Himalayan
pandas).
In
addition,
we
explore
how
studies
have
provided
insight
into
convergent
adaptation
to
diet.
Finally,
discuss
findings
applied
effective
conservation
management
captivity
promote
long-term
persistence
species.
Molecular Biology and Evolution,
Год журнала:
2023,
Номер
40(12)
Опубликована: Дек. 1, 2023
Abstract
Animals
consume
a
wide
variety
of
food
sources
to
adapt
different
environments.
However,
the
genetic
mechanisms
underlying
acquisition
evolutionarily
novel
feeding
morphology
remain
largely
unknown.
While
nematode
Caenorhabditis
elegans
feeds
on
bacteria,
satellite
species
Pristionchus
pacificus
exhibits
predatory
behavior
toward
other
nematodes,
which
is
an
habit.
Here,
we
found
that
astacin
metalloprotease
Ppa-NAS-6
required
for
killing
by
P.
pacificus.
Ppa-nas-6
mutants
were
defective
in
predation-associated
characteristics,
specifically
tooth
morphogenesis
and
movement
during
predation.
Comparison
expression
patterns
rescue
experiments
nas-6
C.
suggested
alteration
spatial
NAS-6
may
be
vital
acquiring
predation-related
traits.
Reporter
analysis
promoter
revealed
was
caused
evolutionary
changes
cis-
trans-regulatory
elements.
This
study
suggests
co-option
involved
morphology.
