Single-cell analysis of the amphioxus hepatic caecum and vertebrate liver reveals genetic mechanisms of vertebrate liver evolution
Nature Ecology & Evolution,
Год журнала:
2024,
Номер
8(10), С. 1972 - 1990
Опубликована: Авг. 16, 2024
Язык: Английский
Resequencing of reindeer genomes provides clues to their docile habits
Evolution Letters,
Год журнала:
2024,
Номер
8(4), С. 494 - 504
Опубликована: Март 5, 2024
Reindeer
have
long
been
served
as
vital
subsistence
resources
for
inhabitants
of
Arctic
and
subarctic
regions
owing
to
their
domestication.
However,
the
evolutionary
relationships
divergence
times
among
different
reindeer
populations,
genetic
traits
that
distinguish
domesticated
reindeer,
factors
contribute
relative
docility
compared
with
other
Cervidae
specie,
remain
unclear.
In
this
study,
we
sequenced
genomes
32
individuals
from
wild
domestic
populations
inhabit
regions.
We
found
experienced
2
or
more
independent
domestication
events
characterized
by
weak
artificial
selection
pressure
limited
significant
differences
in
genomic
parameters
between
populations.
Alterations
conserved
noncoding
elements
genomes,
particularly
those
associated
nervous
system
development,
may
contributed
rendering
less
responsive.
Together,
our
results
suggest
inherent
species-specific
traits,
rather
than
intense
selection,
played
a
role
relatively
docile
behavior
offer
valuable
insights
into
process
these
animals.
Язык: Английский
Haplotype resolved chromosome-level genome assembly of the gold barb (Barbodes semifasciolatus)
Scientific Data,
Год журнала:
2025,
Номер
12(1)
Опубликована: Май 29, 2025
The
gold
barb
(Barbodes
semifasciolatus),
a
member
of
the
Cyprinidae
family,
exhibits
remarkable
adaptability
to
highly
acidic
environments,
making
it
an
ideal
model
for
studying
extreme
environmental
adaptation.
However,
its
genome
has
not
been
previously
characterized.
To
address
this,
we
assembled
high-quality
chromosome-scale
B.
semifasciolatus
using
High-Fidelity
(HiFi)
sequencing
and
Hi-C
technology.
resulting
haplotype-resolved
assemblies,
spanning
776
Mb
779
across
25
chromosomes,
achieved
coverages
99.5%
99.7%,
respectively,
included
four
gap-free
chromosomes.
Genome
quality
assessment
BUSCO
indicated
high
completeness
score
98.2%
haplotype1
98.3%
haplotype2,
further
validated
by
strong
synteny
with
zebrafish
(Danio
rerio),
confirming
assembly's
integrity
continuity.
Through
integration
full-length
transcriptome
data,
RNA
sequencing,
homology-based
annotation,
identified
26,057
protein-coding
genes
2,087
pseudogenes
in
haplotype
2,
25,622
2,101
1.
This
high-resolution
assembly
is
crucial
resource
advancing
research
Cyprinidae,
particularly
understanding
adaptive
evolution
environments.
Язык: Английский
Slc43a2+ T cell metastasis from spleen to brain in RGNNV infected teleost
Science China Life Sciences,
Год журнала:
2024,
Номер
67(4), С. 733 - 744
Опубликована: Фев. 21, 2024
Язык: Английский
Relative sarcolipin (SLN) and sarcoplasmic reticulum Ca2+ ATPase (SERCA1) transcripts levels in closely related endothermic and ectothermic scombrid fishes: Implications for molecular basis of futile calcium cycle non-shivering thermogenesis (NST)
Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology,
Год журнала:
2024,
Номер
295, С. 111667 - 111667
Опубликована: Май 22, 2024
Regional
endothermy
is
the
ability
of
an
animal
to
elevate
temperature
specific
regions
body
above
that
surrounding
environment
and
has
evolved
independently
among
several
fish
lineages.
Sarcolipin
(SLN)
a
small
transmembrane
protein
uncouples
sarcoplasmic
reticulum
calcium
ATPase
pump
(SERCA1b)
resulting
in
futile
Ca
Язык: Английский
Convergent degenerated regulatory elements associated with limb loss in limbless amphibians and reptiles
Molecular Biology and Evolution,
Год журнала:
2024,
Номер
41(11)
Опубликована: Ноя. 1, 2024
Abstract
Limbs
are
a
defining
characteristic
of
tetrapods,
yet
numerous
taxa,
primarily
among
amphibians
and
reptiles,
have
independently
lost
limbs
as
an
adaptation
to
new
ecological
niches.
To
elucidate
the
genetic
factors
contributing
this
convergent
limb
loss,
we
present
12
Gb
chromosome-level
assembly
Banna
caecilian
(Ichthyophis
bannanicus),
limbless
amphibian.
Our
comparative
analysis,
which
includes
reconstruction
amphibian
karyotype
evolution,
reveals
constrained
gene
length
evolution
in
subset
developmental
genes
across
3
large
genomes.
Investigation
development
uncovered
loss
Grem1
caecilians
Tulp3
snakes.
Interestingly,
snakes
share
significantly
larger
number
degenerated
conserved
noncoding
elements
than
lizards,
shorter
evolutionary
history
loss.
These
overlap
with
active
genomic
regions
during
mouse
limbed
species,
suggesting
their
essential
role
patterning
tetrapod
common
ancestor.
While
most
emerged
jawed
vertebrate
ancestor,
coinciding
origin
paired
appendage,
more
recent
also
contribute
development,
demonstrated
through
functional
experiments.
study
provides
novel
insights
into
regulatory
associated
offering
perspective
on
basis
morphological
specialization.
Язык: Английский