Integrated multidisciplinary approach to aneurysm hemodynamic analysis: numerical simulation, in Vitro experiment, and deep learning DOI Creative Commons
Tingting Fan, Jun Wang, Xu Wang

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13

Опубликована: Июнь 3, 2025

Aneurysm, as life-threatening vascular pathologies, are significantly influenced by hemodynamic factors in their development. The combine of numerical simulation and vitro experiment have laid the foundation for high-precision analysis, while integration deep learning technologies has enhanced computational efficiency. However, current researches still face challenges such limitations biomimetic materials, incomplete understanding mechano-biological coupling mechanisms. In this review, we systematize traditional emerging methodologies characterizing perturbations across pathophysiological continuum aneurysmal expansion, rupture, thrombosis progression. This review aims to (1) elucidate mechanistic underpinnings aneurysm destabilization, (2) inspire people establish standardized quantification protocols (3) pave way patient-specific risk stratification enabling data-driven clinical interventions.

Язык: Английский

Integrated multidisciplinary approach to aneurysm hemodynamic analysis: numerical simulation, in Vitro experiment, and deep learning DOI Creative Commons
Tingting Fan, Jun Wang, Xu Wang

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13

Опубликована: Июнь 3, 2025

Aneurysm, as life-threatening vascular pathologies, are significantly influenced by hemodynamic factors in their development. The combine of numerical simulation and vitro experiment have laid the foundation for high-precision analysis, while integration deep learning technologies has enhanced computational efficiency. However, current researches still face challenges such limitations biomimetic materials, incomplete understanding mechano-biological coupling mechanisms. In this review, we systematize traditional emerging methodologies characterizing perturbations across pathophysiological continuum aneurysmal expansion, rupture, thrombosis progression. This review aims to (1) elucidate mechanistic underpinnings aneurysm destabilization, (2) inspire people establish standardized quantification protocols (3) pave way patient-specific risk stratification enabling data-driven clinical interventions.

Язык: Английский

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